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52 results for “malignant”
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Research ArticleOpen accessIn the abstractDihydroartemisinin Attenuates HBV-Induced Proliferation and Migration in LO2 cells via EMT Pathway ModulationYingde Nong, Caifang Ma, Wei Huang et al.Dihydroartemisinin (DHA), a derivative of artemisinin, possesses well-documented anti-inflammatory properties. This study investigated the inhibitory effects of DHA on hepatitis B virus (HBV)-induced cellular alterations in LO2 cells and elucidated underlying molecular mechanisms. Serum interleukin-6 (IL-6) levels were measured in HBV patients and analyzed for correlations with HBsAg, anti-HBs, and HBeAg. In vitro, LO2 cells were infected with clinical HBV … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 3 · 8 Jan 2026 · 2,071 accessesView PDFCite
Research ArticleOpen accessIn the abstractHybrid CNN-Based Transformer Pipeline With Radiomic Fusion for Multi-Class Lung Cancer DetectionAanchal Vij, Kuldeep Singh Kaswan, Anand NayyarEarly detection of lung cancer remains challenging due to high intra-class variation and inter-class similarity in Computed Tomography (CT) images. In this paper, we propose a hybrid deep learning model that combines convolutional, attention-based, and transformer-guided representations to address these challenges in multi-class lung cancer classification. For deep feature extraction, we use the EfficientNetV2-S architecture augmented with a Convolutional Block … …Journal of Computer Science, Vol. 22, Issue 6 · 3 Jun 2026 · 1,528 accessesView PDFCite
Research ArticleOpen accessIn the abstractEmploying Hybrid Serial Cascaded Adaptive Network for Anomaly Detection and Prevention in IoT Time Series Data With Optimal Interdomain RoutingKante Satyanarayana, K. VenkateshNowadays, emerging Internet of Things (IoT) in data processing becomes interested research topic and is used for various applications. This varies from big data processing and analytics for accumulating entire sensor data to detect and generate long-term trends. Nevertheless, this results in the requirement for resources like the execution of power, memory, and bandwidth, in which resource-constrained IoT tools suffers … …Journal of Computer Science, Vol. 22, Issue 1 · 21 Feb 2026 · 1,466 accessesView PDFCite
Research ArticleOpen accessIn the abstractCuckoo Search Optimized Random Forest for Breast Cancer PrognosisPrasad S. Sase, Debabrata Swain, Shailesh KumarBreast cancer remains a major global health concern due to its high mortality rate, particularly when diagnosis occurs at an advanced stage. Accurate and early differentiation between benign and malignant tumors is therefore critical for improving patient outcomes. Conventional diagnostic practices largely depend on manual assessment and clinical expertise, which may lead to subjective variability in decision-making. To overcome this … …Journal of Computer Science, Vol. 22, Issue 1 · 31 Jan 2026 · 2,098 accessesView PDFCite
Research ArticleOpen accessIn the abstractHematologic Cancer Cell Detection and Classification Using Optimized VGG-19 with Stratified K-fold Cross-ValidationHema Patel, Himal Shah, Gayatri Patel, Atul PatelThe most prevalent pediatric blood malignancy is acute lymphoblastic leukemia (ALL). ALL is a lethal disease in which patients have a lower survival rate. Its prompt detection and precise categorization are essential for successful treatment. Manual microscopic diagnosis is laborious, prone to mistakes, and heavily reliant on specialized knowledge. With stratified 7-fold cross-validation, which assures an equal ratio of normal … …Journal of Computer Science, Vol. 21, Issue 11 · 24 Dec 2025 · 1,812 accessesView PDFCite
Review ArticleOpen accessIn the abstractUnveiling Skin Cancer: A Review of Deep Learning Techniques for DetectionGoutham Lal Shanmughamadom Harilal, Tamilselvi PanneerselvamEarly identification is essential for successful treatment and better patient outcomes since skin cancer is caused by damage to DNA in skin cells, which can result in genetic abnormalities and the possibility of metastasis. The present systematic review scrutinizes the efficacy and obstacles of early detection techniques, which differentiate between benign and malignant lesions by examining lesion attributes such as … …Journal of Computer Science, Vol. 21, Issue 9 · 23 Oct 2025 · 2,602 accessesView PDFCite
EditorialOpen accessIn the abstractAssociation between Infective Endocarditis and Premalignant Colorectal LesionsCarles FalcesThe association between Infective Endocarditis (IE) and Colorectal Cancer (CRC) has been known for more than 50 years. The microorganisms in which this association has been described are Streptococcus gallolyticus (formerly Streptococcus bovis) (Corredoira-Sánchez et al., 2012; Boleij et al., 2011), in different subspecies and, more recently, Enterococcus faecalis (Pericàs et al., 2016; 2017; Escolà-Vergé et al., 2020; Pericàs et … …American Journal of Infectious Diseases, Vol. 17, Issue 3 · 10 Jun 2021 · 11,559 accessesView PDFCite
Research ArticleOpen accessIn the abstractRelationship between Streptococcus gallolyticus Infective Endocarditis and Pre-Neoplastic Colorectal LesionsPau Vilardell, Sergio Moral, Josep Maria Frigola et al.Colorectal cancer is associated with Infective Endocarditis (IE) due to specific gut pathogens, such as Streptococcus gallolyticus subspecies, that use tumor presence as a point of blood entry. However, the association between Streptococcus gallolyticus related IE and pre-cancerous colorectal lesions like dysplastic adenomas is unclear. Seventy-one patients diagnosed with IE who underwent colonoscopy in the extension study during admission were … …American Journal of Infectious Diseases, Vol. 17, Issue 3 · 28 May 2021 · 7,131 accessesView PDFCite
Research ArticleOpen accessIn the abstractSelective Susceptibility of Human Bladder Transitional Cell Carcinoma T24 Cells towards NBD PeptideSankari Durairajan, Charles Emmanuel Jebaraj Walter, Kalaiselvi Periyandavan et al.Bladder cancer is a recurrent disease that often develops chemoresistance and is on the rise in developing countries. After diagnosis surgery followed by immunotherapy and/or chemo- radiation therapy are the available treatments. These treatments do not provide protection against disease progression or recurrence thus highlighting the need to identify and develop drugs that are capable of inhibiting bladder cancer. T24 … …American Journal of Biochemistry and Biotechnology, Vol. 16, Issue 2 · 20 Apr 2020 · 7,787 accessesView PDFCite
Research ArticleOpen accessIn the abstractIdentification of Cancer: Mesothelioma’s Disease Using Logistic Regression and Association RuleAvishek ChoudhuryMalignant Pleural Mesothelioma (MPM) or malignant mesothelioma (MM) is an atypical, aggressive tumor that matures into cancer in the pleura, a stratum of tissue bordering the lungs. Diagnosis of MPM is difficult and it accounts for about seventy-five percent of all mesothelioma diagnosed yearly in the United States of America. Being a fatal disease, early identification of MPM is crucial … …American Journal of Engineering and Applied Sciences, Vol. 11, Issue 4 · 7 Dec 2018 · 7,224 accessesView PDFCite