17 results for “hypoxia”

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Research ArticleOpen accessIn the abstractComparative Functional Analysis of the Basic Helix-Loop-Helix Proteins in the Clawed Frogs' Genomes With Common Essential Pathways and Enriched Gene Ontology TermsWuyi LiuThe international Gene Ontology (GO) and pathway databases were used to functionally analyze the clawed frogs' Basic Helix-Loop-Helix (bHLH) transcription factors of Xenopus tropicalis and Xenopus laevis in a updated genome-wide survey. There were 41 GO terms and one pathway significantly enriched for Xenopus tropicalis, whereas there were 45 GO terms and 3 pathways significantly enriched for Xenopus laevis. Among … …American Journal of Biochemistry and Biotechnology, Vol. 15, Issue 1 · 28 Mar 2019 · 8,490 accessesView PDF Cite

Research ArticleOpen accessIn the abstractImpact of Acute Bronchiolitis on Cardiac Functions and Serum microRNA-122 and 499Mona Abd El-Gelel Mohamed, Khalid Mahmoud ZayedBronchiolitis is an acute inflammatory injury of the bronchioles that is usually caused by a viral infection, most commonly Respiratory Syncytial Virus (RSV). This study aimed to verify the direct injurious effect of acute bronchiolitis on the myocardium and serum level of microRNA-122 and 499 (miR-122 and miR-499) of infected infants. Serum lactate dehydrogenase (LDH), creatine phosphokinase-isoenzyme MB (CK-MB) and … …American Journal of Infectious Diseases, Vol. 12, Issue 1 · 26 Jan 2016 · 7,250 accessesView PDF Cite

Research ArticleOpen accessIn the abstractATRA AS A POTENTIAL ANTIMETASTATIC AGENT IN COLORECTAL ADENOCARCINOMARobert Edwards, Kambiz Afrasiabi, Kehui WangThe family of Retinoic acid compounds have long been the subject of intense study and interest as chemo prophylactic agents. This dates back to their therapeutic effect in leukoplakia Where ATRA was shown to lead to the reversal of premalignant lesions and Subsequent reports on their use in metastatic colorectal adenocarcinoma and a vast array of other malignant disorders as … …OnLine Journal of Biological Sciences, Vol. 14, Issue 2 · 26 Mar 2014 · 7,344 accessesView PDF Cite

Research ArticleOpen accessIn the abstractMaternal Infection and Neurodevelopmental Disorders in the OffspringHeping ZhouProblem statement: Neurodevelopmental disorders such as schizophrenia and autism have been attributed to both genetic and environmental factors. Whether and how maternal infection as an environmental factor contributes to the development of neurological abnormalities in the offspring remains to be clearly defined. Approach: The literature was reviewed to examine the relationship between maternal infection and neurological disorders such as schizophrenia … …American Journal of Immunology, Vol. 8, Issue 1 · 12 Mar 2012 · 8,150 accessesView PDF Cite

Research ArticleOpen accessIn the abstractEffects of Hyperoxia on Brain Tissue Oxygen Tension in Non-Sedated, Non- Anesthetized Arctic Ground Squirrels: An Animal Model of Hyperoxic StressYilong Ma, Shufen Wu, Lawrence DuffyArctic Ground Squirrels (AGS) are classic hibernators known for their tolerance to hypoxia. AGS have been studied as a model of hypoxia with potential as a medical research model. Problem statement: Their unique resistance to the stressors of low oxygen led us to hypothesize that AGS might also be adaptable to hyperoxia. Approach: This study examined the physiological pattern associated … …American Journal of Animal and Veterinary Sciences, Vol. 6, Issue 1 · 26 Apr 2011 · 8,473 accessesView PDF Cite

Research ArticleOpen accessIn the abstractThe Effect of High Altitude on Blood Hormones in Male Westar Rats in South Western Saudi ArabiaFahaid H. Al-HashemProblem statement: Living in high altitude areas results in chronic hypoxia, which induces complex metabolic and endocrine adaptations. The current study investigated the endocrine responses of male Westar rats chronically exposed to high altitude-induced hypoxia in Abha City, in Southwestern Saudi Arabia. Approach: The rats were separated in to 2 groups of 10 rats. The first group was kept at … …American Journal of Environmental Sciences, Vol. 6, Issue 3 · 30 Jun 2010 · 7,202 accessesView PDF Cite

Research ArticleOpen accessIn the abstractEffects of N-Acetylcysteine on Auditory Brainstem Response Threshold Shift in Rabbits Exposed to Noise and Carbon MonoxideSeyedbagher Mortazavi, Masoud Motalebi Kashani, Ali Khavanin et al.Problem statement: Noise Induced Hearing Loss (NIHL) is one of the most important occupational disease in worldwide. NIHL has been found to be potentiated by simultaneous Carbon monoxide (CO) exposure. Exposure to noise plus CO is common in occupational and environmental settings. Free radicals have been implicated in cochlear damage resulting from exposure to noise and due to CO hypoxia … …American Journal of Applied Sciences, Vol. 7, Issue 2 · 28 Feb 2010 · 8,040 accessesView PDF Cite