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57 results for “human immunodeficiency”
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Research ArticleOpen accessPhrase in the titleHormonal and Metabolic Disorders of Human Immunodeficiency Virus Infection and Substance AbuseJag H. Khalsa, Frank Vocci, Adrian DobsThere are an estimated 200 million users of an illicit drug in the world today. In addition, an estimated 40 million people are infected with the human immunodeficiency virus (HIV) and an estimated 180 million people are infected with the hepatitis C virus (HCV). Both the use of an illicit drug and the co-occurrence of infections are associated with a … …American Journal of Infectious Diseases, Vol. 2, Issue 3 · 30 Sep 2006 · 6,715 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleAudit of the Quality of Data on Human Immunodeficiency Virus Infection in 2022 in Burkina FasoIsmaël Diallo, Maurice Sarigda et al.Burkina Faso pledged to reach the worldwide objective of eliminating HIV/AIDS by 2030. Therefore, its information system must be able to provide quality data for monitoring and evaluating progress. This study assessed the quality of data on HIV/AIDS in Burkina Faso. We conducted an audit on the promptitude, exhaustivity, and exactitude in the management of data regarding HIV/AIDS. The survey … …American Journal of Infectious Diseases, Vol. 21, Issue 1 · 5 Jul 2025 · 5,753 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleClinical and Sociodemographic Risk Factors for Tuberculosis in Human Immunodeficiency Virus Infected PatientsPaz-Ayar Nibardo, Jose Antonio Mata-Marin, Jesus Gaytan-Martinez et al.To identify clinical and sociodemographic factors associated with the risk of tuberculosis in HIV-infected patients. A case-control study in a cohort of HIV-infected patients. Cases: patients coinfected with HIV and pulmonary or extrapulmonary tuberculosis. Controls: no clinical tuberculosis and PPD negative, matched for age and sex. Primary data were obtained from medical records and personal interviews. We identified 47 cases … …American Journal of Infectious Diseases, Vol. 9, Issue 4 · 30 Nov 2013 · 8,236 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleCo-Inhibitory Molecule Programmed Death-1 and its Ligands: A New Alternative Therapy for Human Immunodeficiency Virus Infection?A. Leon-Flores, P. Del Rio, G. Reyes-TeranChronic viral infections are characterized by the up-regulation of a set of immunomodulatory receptors. The over-expression of co-inhibitory molecules on T cells leads to a dysfunctional T cell response with an "exhausted" phenotype. Programmed Death-1 (PD-1) is a molecule that exerts an inhibitory signal on the T cell receptor when it binds to the PD-L1 or PD-L2 ligands present on … …American Journal of Infectious Diseases, Vol. 8, Issue 4 · 28 Dec 2012 · 6,962 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleInnate, Adaptive and Intrinsic Immunity in Human Immunodeficiency Virus InfectionSuneth S. Perera, Nitin K. SaksenaThe first line of defence of the innate immune system functions by recognizing highly conserved sets of molecular structures specific to the microbes, termed pathogen-associated molecular patterns, or PAMPs via the germ line-encoded receptors Pattern-Recognition Receptors (PRRs). In addition to the innate immune system, the vertebrates have also evolved a second line of defence termed adaptive immune system, which uses … …American Journal of Infectious Diseases, Vol. 8, Issue 3 · 27 Nov 2012 · 9,723 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleEfficacy of an Oral Health-Promoting Program in Human Immunodeficiency Virus-Infected Children: A 7-year Longitudinal StudyNathalia Ferraz Oliscovicz, Gloria Fernanda Barbosa de Araújo Castro, Luciana Pomarico, Ivete Pomarico Ribeiro de SouzaProblem statement: Children infected with HIV have a higher prevalence of caries in both dentitions. With that in mind, it is important the introduction of programmes for the control of caries disease in this population. Thus, this study was aimed to assess the efficacy of an oral health-promoting program in controlling caries in HIV-infected children after 7 years of follow-up. … …American Journal of Infectious Diseases, Vol. 8, Issue 2 · 30 Jul 2012 · 7,907 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleMicrobial Translocation and B Cell Dysfunction in Human Immunodeficiency Virus DiseaseWei JiangThe gut mucosal barrier disrupted in HIV disease, resulting in increased systemic exposure to microbial products such as Lipo Polys Accharide (LPS). The association of enhanced microbial translocation and B cell dysfunction in HIV disease is not fully understood. High dose and short term exposure of microbial Toll-Like Receptor (TLR) agonists were used as vaccine adjuvants, however, low dose and … …American Journal of Immunology, Vol. 8, Issue 2 · 30 Jun 2012 · 7,409 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleAn Exceptional Case Report of Primary Cutaneous Cryptococcosis in Human Immunodeficiency VirusA. S. Valan, S. Kumar, K. Ramalingam et al.Problem statement: Cryptococcosis is an infection caused by the encapsulated yeast Cryptococcus neoformans, a dimorphic fungus. In patients with AIDS, skin manifestations represent the second most common site of disseminated Cryptococcosis. Approach: Mr. A 42 year old farmer was referred from Voluntary Counseling and Testing Centre (VCTC) with positive HIV status to the outpatient department with one week history of … …American Journal of Immunology, Vol. 7, Issue 1 · 16 Aug 2011 · 8,278 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleFrequency of P/S(XX)P Duplication and FRFE, Absence of LYP in P6Gag of Indian Human Immunodeficiency Virus-1 Subtype C IsolatesKrutika Wadekar, Sudhanshu Pandey, Preeti Jain et al.Problem statement: The presence of a p6 domain at the C-terminus of the Gag polyprotein is a characteristic feature of HIV-1 and other primate lentiviruses. The p6Gag protein is considered as a major phosphoprotein in mature HIV-1 virions and is involved in the viral assembly and budding process. Sequence variation in the p6gag region in HIV-1 has been associated with … …Current Research in Medicine, Vol. 1, Issue 2 · 31 Oct 2010 · 7,529 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleAnalysis of Resistance to Human Immunodeficiency Virus Protease Inhibitors Using Molecular Mechanics and Machine Learning StrategiesA. Harishchander, D. Alex Anand, Sanjib SenapatiProblem statement: Drug resistance is the most important factor, which influences the failure of current HIV therapies. So, the ability to predict the drug resistance of HIV-1 protease mutants will be useful in developing more effective and longer lasting treatment regimens. Approach: Drug resistance of HIV-1 protease is predicted with two current protease inhibitors (Indinavir and Saquinavir). The problem was … …Current Research in Medicine, Vol. 1, Issue 2 · 31 Oct 2010 · 7,204 accessesView PDFCite