22 results for “folding”

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Research ArticleOpen accessIn the keywordsSpecialization of Recursive Predicates from Positive Examples OnlyMoussa DembaProblem statement: Given an overly general (definite) program P and its intended semantics Φ (the programmer’s intentions) where P does not satisfy Φ, find out a new version P’ of P such that P’ satisfies Φ. Approach: We proposed an approach for correcting overly general programs from positive examples by exploiting program synthesis techniques. The synthesized program, P’, is a … …Journal of Computer Science, Vol. 6, Issue 6 · 30 Jun 2010 · 6,854 accessesView PDF Cite

Research ArticleOpen accessIn the abstractCytocompatibility and Antimicrobial Properties of Silver Nanoparticles-Loaded AMPs in the Oral CavityYanli Lv, Weikai ZhangPostoperative infection following oral metal implantation is a key factor that affects the success rate of surgery. This infection is mainly caused by bacterial biofilms. Traditional single antibacterial coatings have limitations, including a narrow antibacterial spectrum and poor cytotoxicity or stability. This study combined silver nanoparticles (AgNPs) and the synthetic antimicrobial peptide GL13K using electrostatic self-assembly technology to create a … …American Journal of Biochemistry and Biotechnology, Vol. 22, Issue 1 · 24 Apr 2026 · 1,685 accessesView PDF Cite

Research ArticleOpen accessIn the abstractComparative Study: Algorithms for Short Message Service ClassificationEvaristus Didik Madyatmadja, Aldi, Fiona Fheren et al.This research aims to classify Short Message Service (SMS) data by applying classification models that have studied SMS data to classify SMS data into SMS spam and SMS ham. The classification model is made from data mining algorithms: Naive Bayes and support vector machine. Before implementing the two algorithms, the SMS data will go through a text preprocessing stage, including … …Journal of Computer Science, Vol. 19, Issue 11 · 29 Sep 2023 · 4,992 accessesView PDF Cite

Research ArticleOpen accessIn the abstractFrequencies of the C1236T, G2677T/A, and C3435T Polymorphisms of the MDR1 Gene and their Haplotypes in UzbekistanS. B. Nurmatova, A. A. Abdurakhimov, O. S. Charishnikova et al.P-glycoprotein (P-gp) is encoded by the MDR1 gene and is involved in the pharmacokinetics of drugs. The best-known MDR1 gene polymorphisms are 1236C>T, 3435C>T, and 2677G>T/A, which are associated with protein folding, changes in mRNA levels, and drug pharmacokinetics. The aim of this study was to identify the frequency of distribution of functional polymorphisms C1236T, C3435T, G2677T/A of the MDR1 … …American Journal of Biochemistry and Biotechnology, Vol. 18, Issue 4 · 5 Dec 2022 · 5,022 accessesView PDF Cite

Research ArticleOpen accessIn the abstractA Meat-Derived Lactic Acid Bacteria, Lactobacillus plantarum IIA, Expresses a Functional Parvulin-Like Protein with Unique Structural PropertyCahyo Budiman, Irma Isnafia Arief, Fernandes Opook, Muhammad YusufThe genome sequence of a Lactic Acid Bacterium (LAB) Lactobacillus plantarum IIA contains a single gene encoding a parvulin-like protein (Par-LpIIA). This protein belongs to Peptidyl Prolyl cis-trans Isomerase (PPIase) family proteins that catalyze a slow cis-trans isomerization of cis prolyl bond during protein folding. This study aims to provide molecular and biochemical evidences of the existence of Par-LpIIA in … …OnLine Journal of Biological Sciences, Vol. 21, Issue 1 · 26 Feb 2021 · 7,023 accessesView PDF Cite

Research ArticleOpen accessIn the abstractThe Endoribonuclease Domain of IRE1 and its Substrate HAC1 are Structurally Linked Components of the Unfolded Protein Response in FungiLuis David Maldonado-BonillaThe unfolded protein response sustains the folding capacity of the endoplasmic reticulum under conditions that increase the activity of the secretory pathway. In fungi, the unfolded protein response exclusively depends on the kinase/endoribonuclease IRE1, which senses the accumulation of unfolded proteins in the endoplasmic reticulum lumen and catalyzes the committed step in the unconventional splicing of HAC1 mRNA that encodes … …American Journal of Biochemistry and Biotechnology, Vol. 16, Issue 4 · 14 Oct 2020 · 6,541 accessesView PDF Cite

Research ArticleOpen accessIn the abstractEvaluation of Polymorphisms at Heat Shock Protein 90 Gene by High Resolution Melting Assays for Potential Heat Tolerance among Nigerian Zebu Cattle BreedsGbolabo Onasanya, George Msalya, Aranganoor Thiruvenkadan et al.Heat Shock Protein (HSP) 90 gene is a member of HSPs sub-family that act as molecular chaperons whenever animals come under thermal stress. The genes fulfill essential roles of providing cellular protection, immune response, protein synthesis, protein folding and unfolding, protection from cellular stress, inhibitory apoptosis and adaptation. This study was designed to analyze polymorphisms of HSP 90 and to … …American Journal of Animal and Veterinary Sciences, Vol. 15, Issue 1 · 7 Mar 2020 · 7,258 accessesView PDF Cite

EditorialOpen accessIn the abstractEditorial Commentary: Challenge of Non–AIDS-Defining Cancers (NADCs), Focusing on Trans Activation Response Element (TAR) RNA Embedding ExosomesLechuang Chen, Ge JinGlobally, 37.9 million people were living with HIV at the end of 2018 (Organization, 2018). Cancer is a major cause of mortality and morbidity in AIDS patients and chronically HIV-infected people. With the aid of combination Antiretroviral Therapy (ART), people living with HIV (PLWH) have a longer life span. However, because the virus is not completely eradicated, PLWH under antiretroviral … …American Journal of Immunology, Vol. 15, Issue 1 · 28 Nov 2019 · 6,657 accessesView PDF Cite

Review ArticleOpen accessIn the abstractProtein Sequences Features Extraction for Predicting Beta- Turns and their Types: A ReviewMurtada Khalafallah Elbashir ElfakiBeta-turns are considered to be important secondary structure types that have essential role in molecular recognition, protein folding and stability. They represent 25% of protein structures, therefore they are the most common type of non-repetitive or tight turns structures. Their prediction is considered to be an important issue in bioinformatics and molecular biology, because it provides valuable information and inputs … …Journal of Computer Science, Vol. 15, Issue 9 · 1 Oct 2019 · 7,694 accessesView PDF Cite

Research ArticleOpen accessIn the abstractProcessability of Bulk Metallic GlassesRaffaella Aversa, Daniela Parcesepe, Relly Victoria V. Petrescu et al.Microfluidic Shear Flow Instabilities in Injection Molded Glassy Metal are investigated. The formation of microfluidic shear flows instabilities involving the presence of different viscosities fluids has been observed in injection molded Bulk Metallic Glasses. The complex rheology of injection molded metastable glassy metal, which has been hypothesized to induce selective clustering of atoms of different steric hindrance, is discussed. Smaller … …American Journal of Applied Sciences, Vol. 14, Issue 2 · 15 Feb 2017 · 7,487 accessesView PDF Cite