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EditorialOpen accessIn the abstractImpact of Quantitative Pharmacology on Drug DevelopmentAna Ruiz-Garcia, Kourosh ParivarThesuccess of drug development rests over two well defined pillars, a goodunderstanding of the drug’s clinical pharmacology and the appropriate targetpopulation for whom the clinical use is intended. The label for human prescription drugsrequires a good understanding of the pharmacological effects (pharmacodynamicsor PD) and the mechanism of action of the drug as well as detailed informationof the drug’s Pharmacokinetics (PK): … …American Journal of Pharmacology and Toxicology, Vol. 9, Issue 4 · 24 Apr 2015 · 7,158 accessesView PDFCite
Research ArticleOpen accessIn the abstractAn Efficient Fault Tolerant Scheduling Approach for Computational GridP. Keerthika, N. KasthuriGrid computing serves as an important technology to facilitate distributed computation computational grids solve large scale scientific problems using heterogeneous geographically distributed resources. Problems like dispatching and scheduling of tasks are considered as major issues in computational grid environment. The Grid Scheduler must select proper resources for executing the tasks with less response time. There are various reasons such as … …American Journal of Applied Sciences, Vol. 9, Issue 12 · 5 Jan 2013 · 6,995 accessesView PDFCite
Research ArticleOpen accessIn the abstractA Novel Multidictionary Based Text CompressionM. Baritha Begum, Y. VenkataramaniThe amount of digital contents grows at a faster speed as a result does the demand for communicate them. On the other hand, the amount of storage and bandwidth increases at a slower rate. Thus powerful and efficient compression methods are required. The repetition of words and phrases cause the reordered text much more compressible than the original text. On … …Journal of Computer Science, Vol. 8, Issue 12 · 8 Nov 2012 · 6,942 accessesView PDFCite
Research ArticleOpen accessIn the abstractDynamic Scheduling for Cloud Reliability using Transportation ProblemS. K. Senthil Kumar, P. BalasubramanieProblem statement: Cloud is purely a dynamic environment and the existing task scheduling algorithms are mostly static and considered various parameters like time, cost, make span, speed, scalability, throughput, resource utilization, scheduling success rate and so on. Available scheduling algorithms are mostly heuristic in nature and more complex, time consuming and does not consider reliability and availability of the cloud … …Journal of Computer Science, Vol. 8, Issue 10 · 23 Aug 2012 · 8,332 accessesView PDFCite
Research ArticleOpen accessIn the abstractFunctional Recovery of Upper Limb Post-Stroke: Mental Practice with Motor and Non-Motor ImageryAline Furtado Bastos, Beatriz Cantanhede Carrapatoso, Marco Orsini et al.Problem statement: Mental Practice (MP) with motor imagery consists of a method of training in which motor imagery is used to improve performance. The aim of this study was to investigate the efficacy of MP with motor imagery on motor recovery of the paretic upper limb of post-stroke patients in comparison with MP with non-motor imagery. Approach: Four post-stroke patients … …Current Research in Medicine, Vol. 3, Issue 1 · 29 Mar 2012 · 9,215 accessesView PDFCite
Research ArticleOpen accessIn the abstractA Discrete Event Simulator for Extensive Defense Mechanism for Denial of Service Attacks AnalysisMaryam Tanha, Seyed Dawood Sajjadi Torshizi, S. ShamalaProblem statement: Seeking for defense mechanisms against low rate Denial of Service (DoS) attacks as a new generation of DoS attacks has received special attention during recent years. As a decisive factor, evaluating the performance of the offered mitigation techniques based on different metrics for determining the viability and ability of these countermeasures requires more research. Approach: The development of … …American Journal of Applied Sciences, Vol. 9, Issue 6 · 21 Mar 2012 · 7,470 accessesView PDFCite
Research ArticleOpen accessIn the abstractIntegrated Resource and Cost Management Scheme for Computational GridsV. K. Manavalasundaram, K. DuraiswamyProblem statement: Autonomous decision making and resource scheduling are the main objectives of market-life computational grid. Resource providers and consumers make the scheduling decisions with cost and incentive factors. The two objectives are to maximize the success rate of job execution and to minimize fairness deviation among resources. The challenge is to develop a grid-scheduling scheme that enables individual participants … …Journal of Computer Science, Vol. 8, Issue 4 · 7 Feb 2012 · 6,565 accessesView PDFCite
Research ArticleOpen accessIn the abstractSecure Selection of Multiple Resources Based on Virtual Private Network for Computational GridsG. Kavitha, V. SankaranarayananProblem statement: Grid computing provides a virtual framework for controlled sharing of resources across institutional boundaries. In computational grids, a client application is executed on the available set of resources that satisfy the user QoS requirements. Some applications require exhaustive computation power for execution of its tasks. In general, these tasks are assigned to a single available resource on the … …Journal of Computer Science, Vol. 7, Issue 12 · 22 Oct 2011 · 7,607 accessesView PDFCite
Research ArticleOpen accessIn the abstractA Novel Technique for Web Log mining with Better Data Cleaning and Transaction IdentificationJ. Vellingiri, S. Chenthur PandianProblem statement: In the internet era web sites on the internet are useful source of information for almost every activity. So there is a rapid development of World Wide Web in its volume of traffic and the size and complexity of web sites. Web mining is the application of data mining, artificial intelligence, chart technology and so on to the … …Journal of Computer Science, Vol. 7, Issue 5 · 7 May 2011 · 6,889 accessesView PDFCite
Research ArticleOpen accessIn the abstractAn Investigation of Using Parallel Genetic Algorithm for Solving the Shortest Path Routing ProblemSalman Yussof, Rina Azlin Razali, Ong Hang SeeProblem statement: Shortest path routing is the type of routing widely used in computer network nowadays. Even though shortest path routing algorithms are well established, other alternative methods may have their own advantages. One such alternative is to use a GA-based routing algorithm. According to previous researches, GA-based routing algorithm has been found to be more scalable and insensitive to … …Journal of Computer Science, Vol. 7, Issue 2 · 25 Feb 2011 · 7,617 accessesView PDFCite