16 articles for “drug delivery”

Research ArticleOpen accessIn the abstractDevelopment and Optimization of Plant Extract Loaded Nanoemulsion Mixtures for the Treatment of Inflammatory DisorderMukesh Gohel, Tejal Soni, Lal Hingorani et al.In current study, a nanoemulsion as drug delivery system (NE) of spray dried Boswellia Serrata Extract (BSE) was developed and characterized to compare it in vitro/Ex vivo diffusion with reference formulation. Pseudo-ternary phase diagrams were constructed by phase diagram by aqueous titration method, of which the evaluation method was improved for solubility, Droplet size and transmittance. The formulation of BSE-loaded … …Current Research in Drug Discovery, Vol. 1, Issue 2 · 26 Jan 2015 · 14,064 accessesView PDF Cite

Research ArticleOpen accessIn the abstractPotential Applications of Chitosan Nanoparticles as Novel Support in Enzyme ImmobilizationHoda Jafarizadeh Malmiri, Mohammad Ali Ghaz Jahanian, Aydin BerenjianChitosan is an attractive natural biopolymer from renewable resources with the presence of reactive amino and hydroxyl functional groups in its structure. Due to the good biocompatibility of chitosan, it can be used in magnetic-field assisted drug delivery, enzyme or cell immobilization and many other industrial applications. In the past decade, nanotechnology has been a considerable research interest in the … …American Journal of Biochemistry and Biotechnology, Vol. 8, Issue 4 · 25 Dec 2012 · 11,302 accessesView PDF Cite

Research ArticleOpen accessIn the abstractFormulation and Evaluation of a Novel Needle-Free Hepatitis B Surface Antigen Delivery SystemC. D. Licy, K. Premalatha, Annie Shirwaikar, Arun ShirwaikarProblem statement: Hepatitis B is a major public health problem, killing 1-2 million people annually, despite the introduction of an effective vaccine in 1982. Approximately 400 million persons worldwide have chronic hepatitis B. This is due to problems associated with vaccine delivery, stability and cost. Hence the present challenge in Vaccinology is to develop safer, cheaper and easy-to-deliver forms of … …Current Research in Medicine, Vol. 1, Issue 2 · 30 Oct 2010 · 6,819 accessesView PDF Cite

Research ArticleOpen accessIn the abstractGenerating Treatment Plan in Medicine: A Data Mining ApproachAhmad Mahir Razali, Shahriyah AliThis study reports on a research effort on generating treatment plan to handle the error and complexity of treatment process for healthcare providers. Focus has been given for outpatient and was based on data collected from various health centers throughout Malaysia. These clinical data were recorded using SOAP (Subjective, Objective, Assessment and Plan) format approach as being practiced in medicine … …American Journal of Applied Sciences, Vol. 6, Issue 2 · 28 Feb 2009 · 7,303 accessesView PDF Cite

Research ArticleOpen accessIn the abstractTamoxifen Drug Loading Solid Lipid Nanoparticles Prepared by Hot High Pressure Homogenization TechniquesNagi A. ALHaj, Rasedee Abdullah, Siddig Ibrahim, Ahmad BustamamAs drug delivery systems Nanoparticulate widely investigated because of many advantages such as smaller size, controlled drug release potential, targeting ability, enhancement of therapeutic efficacy and reduction of toxicity. So, Solid Lipid Nanoparticles have recently received considerable attention as alternative drug delivery carrier. In this study Solid Lipid Nanoparticles (SLNs) containing tamoxifen, nonsteroidal antiestrogens have been loaded and to be … …American Journal of Pharmacology and Toxicology, Vol. 3, Issue 3 · 30 Sep 2008 · 15,168 accessesView PDF Cite

Research ArticleOpen accessIn the abstractPreparation and Properties of Copolyanhydrides Based on 2-Hexadecylsuccinic Acid and Sebacic AcidYousef Hamdan, Xiangmei Jiang, Kaixun Huang, Kaichao YuPoly(2-hexadecylsuccinic acid-sebacic acid) (P(HSA-SA)) copolymers have been prepared by melt polycondensation. The copolymers were characterized by FT-IR, 1HNMR, gel permeation chromatography (GPC), differential scanning calorimetry (DSC) and thermal gravimetric analysis (TGA). In vitro studies showed that all our prepared copolymers are degradable in phosphate buffer at 37°C. The release profiles of hydrophilic model drug, ciprofloxcin hydrochloride, from the copolymers, follow … …American Journal of Applied Sciences, Vol. 4, Issue 3 · 31 Mar 2007 · 7,427 accessesView PDF Cite