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570 results for “drug”
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Research ArticleOpen accessEvery word in the titleOutcomes and Risk Factors Associated with Drug Resistant Tuberculosis in Rural Eastern Cape, South AfricaCarine Bokop Fotso, Sandeep D. Vasaikar, Teke ApalataWith the emergence of Multidrug-Resistant (MDR) and Extensively Drug-Resistant (XDR) strains of Mycobacterium tuberculosis, Tuberculosis (TB) has become an even greater threat in South Africa (SA). The study sought to investigate the resistance pattern of anti-TB drugs in M. tuberculosis as well as to determine the associated risk factors and outcomes for MDR-TB and XDR-TB. A descriptive study was conducted … …American Journal of Infectious Diseases, Vol. 14, Issue 2 · 15 Aug 2018 · 9,537 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleMycobacterium tuberculosis Complex Mutations in Drug Resistant Clinical Isolates from Southwest MexicoMartínez-Cruz Perla Mónica, Nakamura-López Yuko, Quintero-Hernández Verónica et al.Mutations in target genes have been described in Mycobacterium tuberculosis Complex (MTBc) drug resistant isolates worldwide. In Mexico, not enough information has been reported in this concern. The aim of this study was to characterize mutations related to resistance to first line drugs in MTBc isolates from Oaxaca, Mexico. MTBc isolates were identified in clinical samples from Tuberculosis (TB) patients. … …American Journal of Infectious Diseases, Vol. 17, Issue 4 · 28 Oct 2021 · 6,669 accessesView PDFCite
Review ArticleOpen accessEvery word in the titleScope and Perspectives of New TB Drugs and VaccinesJaishree Meena, Laxman S. MeenaTuberculosis remains a major threatening infectious disease claiming millions of lives every year; hence increasing the global burden of TB disease. Co-infection with human immuno-deficiency virus and emergence of multi-drug resistant tuberculosis, extremely drug resistant tuberculosis and totally drug resistant tuberculosis enhances deadly effect of tuberculosis. To eliminate TB disease from human population several partnerships are working together like Stop … …American Journal of Infectious Diseases, Vol. 11, Issue 3 · 10 Sep 2015 · 7,946 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleThe Diaspora Nigerians’ Image Problem of Drug and Fraud: A Case Study of the Malaysian-Indonesian Experience through Newspaper ReportsMusa Yusuf Owoyemi, Abdul Kadir Haji Din, Ahmad Zaharuddin Sani Ahmad SabriIt is no longer news that the economic and social problems in Nigeria have led to mass migration of Nigerians to other parts of the world for better job opportunities and/or education. South-East Asia has had its fair intake of some of these Nigerians especially in recent times. However, some unscrupulous Nigerians in their bid to make quick money have … …Journal of Social Sciences, Vol. 11, Issue 2 · 24 Jun 2015 · 7,767 accessesView PDFCite
Research ArticleOpen accessEvery word in the titlePrescription Pattern of Anti-Hypertensive Drugs in Adherence to JNC- 7 GuidelinesKrishna Murti, M. Arif Khan, Akalanka Dey et al.The main objective of the present study to investigate the utilization pattern of antihypertensive drugs in hypertensive patients and to find out whether the prescription pattern is in adherence with the JNC7 guidelines for the management of hypertension. A prospective study was conducted and drug utilization data were collected from 137 hypertensive patients who were attended as Out Patient Department … …American Journal of Pharmacology and Toxicology, Vol. 10, Issue 1 · 2 Jun 2015 · 8,277 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleReverse Pharmacology-A Paradigm Shift for Drug Discovery and DevelopmentAshok D.B. VaidyaThe current scenario of drug discovery and development is facing a model perturbation, despite significant advances in genomics, proteomics, metabolomics, combinatorial chemistry and high through put assays. There is an urgent need of a paradigm shift in approaches to drug discovery. Natural products of Ayurveda offer a vast potential for novel phytomolecules with clinical activity. In India, Ayurveda is availed … …Current Research in Drug Discovery, Vol. 1, Issue 2 · 26 Jan 2015 · 15,404 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleCHITOSAN NANOPARTICLES AND THEIR APPLICATIONS IN DRUG DELIVERY: A REVIEWSharare Najafi, Zahra Pazhouhnia, Omid Ahmadi et al.Chitosan is one of the most popular materials in the field of drug delivery due to its adhesivity and biodegradability. Different types of Chitosan based drug carriers have been conceived for various administration routes, such as oral, nasal, transdermal, parenteral, vaginal, cervical and rectal due to its biocompatibility and biodegradability. Chitosan Nanoparticles (NPs) have long been studied as carriers for … …Current Research in Drug Discovery, Vol. 1, Issue 1 · 8 Nov 2014 · 14,780 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleAMINO ACID TRANSPORTERS IN DRUG DISCOVERYMariafrancesca Scalise, Lorena Pochini, Michele Galluccio, Cesare IndiveriAdministered drugs interact with membrane transporters of epithelia, Blood Brain Barrier and other districts influencing their delivery and efficacy. Drugs can also be used as inhibitors of transporters involved in human pathology. Drug-transporter interactions are responsible of off-target effects contributing to toxicity. High Throughput Screening technologies increased the potential applications in therapy or in predicting side effects. These strategies will … …Current Research in Drug Discovery, Vol. 1, Issue 1 · 2 Oct 2014 · 7,101 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleTHE INFLUENCE OF PERSONALITY ACCENTUATION ON DRUG ADDICTION AMONG STUDENTSElena Aleksandrovna Cheverikina, Andrei Vasilyevich Leifa, Nataliya Alekseyevna Kora et al.To identify character accentuation students who are prone to addiction will allow to adjust their socialization process during the training period in order to increase its effectiveness, as well as it will contribute to the creation of effective psycho-educational programs aimed at reducing the level of their addiction to drugs. Objective: To identify the influence of experimental character accentuation susceptibility … …American Journal of Pharmacology and Toxicology, Vol. 9, Issue 2 · 27 Jun 2014 · 7,739 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleTHE MODEL IN PREVENTING AND SOLVING DRUGS IN THE THAI-LAO BORDER VILLAGESWattana Puttichart, Saner Piromjitpong, Metta MettkarunjitA drug issue is a problem at both national and international levels. The root causes of the problems lie inside and outside the humans. To solve the problems in a sustainable way, it is essential to get cooperation from many parties. The research aimed to study the situations and prevention and solution of drugs in the border villages, to construct … …Journal of Social Sciences, Vol. 10, Issue 1 · 18 Apr 2014 · 7,498 accessesView PDFCite