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28 articles for “dementia”
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Research ArticleOpen accessIn the keywordsNeuropsychological Consequences of HIV and Drug AuseArun Venkatesan, Ola Selnes, Valerie Wojna et al.Accurate assessment of the functional consequences of human immunodeficiency virus (HIV) infection and drugs of abuse are critical as large populations are afflicted with both. Both are interdependent epidemics with important socioeconomic consequences. Experimental studies in animal models and in vitro clearly indicate that HIV and drugs of abuse cause increased neurodegeneration, glial cell activation and enhanced HIV replication. Nevertheless, … …American Journal of Infectious Diseases, Vol. 2, Issue 2 · 30 Jun 2006 · 6,662 accessesView PDFCite
Research ArticleOpen accessIn the abstractFusing CNN Models for Improved Parkinson’s Disease Detection from Handwritten FeaturesSabrina Benredjem, Tahar MekhazniaNeurodegenerative Diseases (NGD) are a group of progressive neurological disorders, including cognitive decline as Alzheimer’s Disease (AD) and Parkinson’s Disease (PD) that result in the progressive loss of neuronal structure or function. This can lead to a variety of symptoms, in this study we are interested in PD one of the neurological diseases that causes the loss of dopamine-producing neurons … …Journal of Computer Science, Vol. 21, Issue 2 · 22 Jan 2025 · 6,306 accessesView PDFCite
Research ArticleOpen accessIn the abstractImage-Based Alzheimer's Disease Detection Using Pretrained Convolutional Neural Network ModelsNasser AlsadhanAlzheimer's disease is an untreatable, progressive brain disorder that slowly robs people of their memory, thinking abilities, and ultimately their capacity to complete even the most basic tasks. Among older adults, it is the most frequent cause of dementia. Although there is presently no treatment for Alzheimer's disease, scientific trials are ongoing to discover drugs to combat the condition. Treatments … …Journal of Computer Science, Vol. 19, Issue 7 · 28 Jun 2023 · 5,909 accessesView PDFCite
Research ArticleOpen accessIn the abstractImproved Classification Model using CNN for Detection of Alzheimer’s DiseaseRagavamsi Davuluri, Ragupathy RengaswamyAlzheimer’s Disease (AD) is commonly called a neurodegenerative disorder and it is a common form of dementia. There is no permanent cure for this brain disease hence the early diagnosis of such disease using medical imaging system is highly significant. Machine learning models play a vital role in the detection of AD. Since most of the conventional machine learning models … …Journal of Computer Science, Vol. 18, Issue 5 · 30 May 2022 · 6,252 accessesView PDFCite
Research ArticleOpen accessIn the abstractAqueous Extracts of Bay Leaf (Laurus nobilis) and Rosemary (Rosmarinus officinalis) Inhibit Iron-Induced Lipid Peroxidation and Key-Enzymes Implicated in Alzheimer’s Disease in Rat Brain-in VitroAyodeji O. Falade, Goodness I. Omolaiye, Kayode E. Adewole et al.Neurological disorders remain a global health challenge, with Alzheimer’s Disease (AD) as the most famous cause of dementia in old people. Nevertheless, culinary spices and herbs have shown promising potentials in the management of neurological diseases. This study aimed at investigating the neuroprotective property of aqueous extracts of bay leaf (Laurus nobilis) and rosemary (Rosmarinus officinalis) by assessing the antioxidant … …American Journal of Biochemistry and Biotechnology, Vol. 18, Issue 1 · 25 Jan 2022 · 7,955 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Effect of a Small Group Life Story Intervention with Rural Community Dwelling Older AdultsLillian Felicia Jones, Mary A. NiesTo determine if a small group life story nursing intervention can be beneficial to rural community dwelling older adults by decreasing depression scores and increasing perceived social support scores. This study employed a quasi-experimental one group pretest/posttest design. This study was conducted in thirteen rural senior facilities with a community population of less than 20,000 in two western states in … …International Journal of Research in Nursing, Vol. 8, Issue 2 · 28 Oct 2017 · 7,499 accessesView PDFCite
EditorialOpen accessIn the abstractWhere the Future is Being Made TodayMark A. Brown, Joachim Storsberg, Christian SchmidtGrowing up, I was fascinated by The Muppet Show and the adventures of Dr. Bunsen Honeydew and his assistant Beaker. Apparently, my feelings were not unique because Muppet characters are used to ease tensions associated with education about clinical interventions (Ramsay, 2014; Rohn, 2007). Yet the opening phrase 'Where the future is being made today' has, in my opinion, summed … …American Journal of Immunology, Vol. 12, Issue 2 · 28 Jun 2016 · 7,425 accessesView PDFCite
EditorialOpen accessIn the abstractAMYOTROPHIC LATERAL SCLEROSIS: HOW TO UNDERSTAND SUCH DIVERSE AND SO ENTANGLED PHYSIOPATHOLOGY?Carlos Henrique Melo Reis, Marco Orsini, Marco Antônio Araujo Leite et al.When in 1865, JeanMartin Charcotreported patients with progressive muscular atrophysuperimposedwith spasticity of inexorable evolution as result of combinedlesions of the anterior horn and lateral column of the spinal cord, hecertainly inaugurated an attempt on the comprehension of one of the mostcomplexes neurological clinical conditions, which until today persists withimmense voids on their comprehension, regardless of the enormous advancesachieved. Astime went … …Current Research in Medicine, Vol. 5, Issue 2 · 16 Feb 2015 · 7,149 accessesView PDFCite
Research ArticleOpen accessIn the abstractPROBABLE CREUTZFELDT JAKOB DISEASE: CASE REPORTYanes Brum Bello, Alexandre Cossenza Pettezzoni De Almeida, Daniela Mendonca Sueth et al.Prion diseases are associated with the accumulation of an abnormal isoformof cellular prion protein (PrPSc), which is the principal constituent of prions. Prions replicate in lymphoreticular tissues before neuroinvasion, suggesting that lymphoreticular biopsy samples may allow early diagnosis by detection of PrPSc. Creutzfeldt-Jakob Disease (CJD) is the most frequent prion disease in humans. Clinical diagnosis of sporadic (CJD) is based … …Current Research in Medicine, Vol. 5, Issue 1 · 14 Mar 2014 · 8,133 accessesView PDFCite
Research ArticleOpen accessIn the abstractCASE REPORT OF A PATIENT WITH RARE P.ARG136CYS (APOE2*) MUTATION IN APOLIPOPROTEIN E GENEJana Lisyova, Jan Chandoga, Stanislav Oravec et al.Apolipoprotein E (apoE) is a polymorphic glycoprotein associated with plasma lipoproteins and plays an essential role in the metabolism and clearance of plasma lipids. ApoE can represent the major genetic risk factor in development of premature atherosclerosis, coronary heart disease and late-onset familial and sporadic Alzheimer’s Disease (AD). We present a case report of a 51-year old male with suspected … …OnLine Journal of Biological Sciences, Vol. 14, Issue 1 · 9 Jan 2014 · 7,295 accessesView PDFCite