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226 articles for “death”
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Research ArticleOpen accessEvery word in the titleMedication Errors: Preventing Untimely DeathsCheryl Ann Alexander, Lidong WangMedication adverse events play a huge role in hospital deaths and morbidity in the US. This plays a large role in the public health of the US at large. Health education is a primary target for those taking medications. A quality assurance or improvement program that is appropriate to capture drug events and measure quality data is essential to prevent … …International Journal of Research in Nursing, Vol. 5, Issue 2 · 19 Jan 2015 · 6,954 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleQuercetin Iron (III) Complex Enhances Radiation-Induced Cell Death in Human Erythroleukemic Cell Lines by Increasing the Generation of Intracellular ROSJiraporn Kantapan, Krai Daowtak, Kachaporn Gateprayoon et al.Quercetin iron (III) complex (IronQ) is a paramagnetic agent which exhibits several biological effects. Despite extensive studies about quercetin metal complex, the role of complexes to enhance the effect of radiation still remains unexplored. To this end, we determined whether and how IronQ sensitizes cancer cells to Ionizing Radiation (IR). Doxorubicin resistant leukemic cells (K562/Adr) and their parental cell lines … …American Journal of Applied Sciences, Vol. 14, Issue 1 · 16 Jan 2017 · 8,064 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleProtection against Lipopolysaccharide-induced Death by An Anti-Interleukin-6 Monoclonal AntibodyBailin Liang, Debra Gardner, Don Griswold, Xiao-yu R. SongSepticemia is frequently associated with serious complications and high mortality despite recent advances in treatment with antibacterial agents. Infectious organisms or their soluble products initiate septic shock through a complex cytokine cascade. Lipopolysaccharide (LPS) induced excessive production of inflammatory cytokines is regarded as a model of septic shock. Experiments of LPS-induced excessive cytokine production were conducted in Balb/c mice for … …American Journal of Immunology, Vol. 3, Issue 1 · 30 Jun 2007 · 6,856 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleCirculating Granzymes are associated with Bloodstream Infection and Death in Febrile Medical PatientsAnnelies N. Tacx, Angela M. Wolbink, C. E. Hack, A.B. Johan GroeneveldPlasma levels of granzymes are specific markers for the activation of cytotoxic T lymphocytes and natural killer (NK) cells but the impact of activation of these cells on the course of bacterial infections is not well understood. We prospectively studied the implications of circulating granzyme A and B (GrA, GrB) levels in febrile, medical and hospitalized patients (n=284), during 3 … …American Journal of Infectious Diseases, Vol. 3, Issue 1 · 31 Mar 2007 · 6,736 accessesView PDFCite
Research ArticleOpen accessIn the keywordsA Novel Characterization of the Incidence Term in Epidemic Models: Interpretation of the Resulting Basic Reproduction Number in Terms of Healthcare AccessibilityFrancis BenyahWe propose a novel characterization of the incidence term in mathematical epidemic models. This new characterization takes into consideration the fact that at any given time, only a proportion $\kappa \ (0 \, \le \, \kappa \, \le \, 1)$, of infectives have access to healthcare. Infectives without access remain untreated and therefore, become reservoirs for new transmissions.The proposed incidence … …Journal of Mathematics and Statistics, Vol. 22, Issue 1 · 1 Oct 2026 · 582 accessesView PDFCite
Research ArticleOpen accessIn the keywordsDistribution, Arrangement and Interconnectedness of Cell Surface Receptor sites in the body of an OrganismUtoh-Nedosa, Uchechukwu AnastasiaCell surface receptors have been identified as the sites of disease infectivity in living organisms in a previous study. Drugs used for the treatment or cure of infections have to eliminate infections through attacking infective organisms at the cell surface receptors to which the infective organisms are attached. Problem statement: The present study examines a wide sample of living things … …OnLine Journal of Biological Sciences, Vol. 11, Issue 4 · 26 Jan 2012 · 7,355 accessesView PDFCite
Research ArticleOpen accessIn the keywordsEffects of ced-9 dsRNA on Caenorhabditis elegans and Meloidogyne incognitaRobert T. Gaeta, Abdellatif Bahaji, Glenda W. Polack, Alejandro Calderón-UrreaAbstract: Problem Statement: In metazoans Programmed Cell Death (PCD) is essential for proper development. Suppression of PCD is needed to guarantee cell survival and in the nematode Caenorhabditis elegans the regulation of PCD is accomplished by the function of the ced-9 gene. Approach: In this work the use of double stranded RNA (dsRNA) to knock-down ced-9 gene function was tested … …American Journal of Agricultural and Biological Sciences, Vol. 6, Issue 1 · 15 Dec 2010 · 9,452 accessesView PDFCite
Research ArticleOpen accessIn the keywordsEarly Cellular Responses of Purine Nucleoside-mediated Protection of Hypoxia-induced Injuries of Neuronal PC12 CellsBettina Tomaselli, Valerie Podhraski, Günther Böck, Gabriele Baier-BitterlichHypoxia in brain may lead to cell death by apoptosis and necrosis. In parallel adenosine, a powerful endogenous neuroprotectant is formed. We wanted to investigate the effect of adenosine and its purine nucleoside relatives, inosine and guanosine on early cellular responses to hypoxia. O2-sensitive neuronal PC12-cells were subjected to chemical hypoxia induced with rotenone, an inhibitor of mitochondrial complex I. … …American Journal of Biochemistry and Biotechnology, Vol. 1, Issue 3 · 30 Sep 2005 · 6,853 accessesView PDFCite
Research ArticleOpen accessIn the keywordsGender, Religion and National Origin: Latinos' Attitude toward Capital PunishmentEllen BaikProblem statement: Previous studies on attitudes toward capital punishment are heavily focused on comparisons between blacks and whites with little attention to the Latino population. This is problematic given the rapid growth of Latino population who is now the largest and fastest-growing ethnic minority in the United States. Approach: Empirical studies devoted exclusively to studying Latinos’ attitude toward capital punishment … …Journal of Social Sciences, Vol. 8, Issue 1 · 26 Jan 2012 · 7,941 accessesView PDFCite
Research ArticleOpen accessIn the keywordsBiochemical Studies on Recombinant Human Isobutyryl-CoA DehydrogenaseNasser E. Ibrahim, Al-Walid A. MohsenProblem statement: Human Isobutyryl-CoA Dehydrogenase (IBD) is member of the Acyl-CoA Dehydrogenases family. It is involved in Val metabolism. In this study we modified the purification method of the IBD and further spectroscopic characterization was conducted. Approach: Using DTT in the buffers during the purification, IBD purified to homogeneity by different chromatographic steps. Reactivity of Cys residues were measured using … …American Journal of Biochemistry and Biotechnology, Vol. 7, Issue 2 · 12 Aug 2011 · 7,539 accessesView PDFCite