13 articles for “core protein”

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Research ArticleOpen accessIn the abstractA Recursive Application of a Support Vector Machine for Protein Spot Detection in 2-Dimensional Gel ElectrophoresisGary D. Boetticher, Hisham Al-Mubaid, Karen Frasier-ScottTwo-dimensional polyacrylamide gel electrophoresis (2-D PAGE) analysis remains the core of proteomic technology because it is currently the most powerful method to analyze large collections of proteins. Advances in electrophoresis equipment are making this technique more accessible but effective computer assisted protein spot detection remains a very labor-intensive endeavor. Protein spot analysis is still time consuming, requires human intervention and … …Journal of Computer Science, Vol. 1, Issue 3 · 30 Sep 2005 · 6,675 accessesView PDF Cite

Research ArticleOpen accessIn the abstractMagnum Opus: Clustered Regularly Interspaced Short Palindromic Repeats Biology and Prokaryotic Gene SilencingPrem Saran Tirumalai, Ashim Kumar BagchiGene Silencing was a technology that was established in eukaryotic system a decade ago and is being used as a research tool widely. However, prokaryotic gene silencing was not workable, till recently a team of researchers from the University of Georgia have proved it possible. Where they have shown that short motif sequences determines the targets of the prokaryotic Clustered … …American Journal of Immunology, Vol. 9, Issue 4 · 5 Oct 2013 · 7,144 accessesView PDF Cite

Research ArticleOpen accessIn the abstractSignaling Pathways Involved In Dengue-2 Virus Infection Induced RANTES OverexpressionYing-Ray Lee, Huan-Yao Lei, Shun-Hua Chen et al.Dengue viruses participate in liver inflammation by inducting the expression of various chemokines including Regulated on Activation Normal T-cell Expressed and Secreted (RANTES). However, the underlying signaling remains unknown. Here, we reveal that Ras, Raf-1 and three mitogen-activated protein kinases (MAPKs) p38, extracellular signal-regulated kinase (Erk), and c-jun-NH2-terminal kinase (JNK) can be activated or phosphorylated in dengue-2 virus infected hepatocyte … …American Journal of Infectious Diseases, Vol. 4, Issue 1 · 31 Mar 2008 · 7,173 accessesView PDF Cite