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44 articles for “cohort study”
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Research ArticleOpen accessIn the abstractAssociation of Remdesivir with Poor Clinical Outcomes in COVID-19-A Single Center ExperienceRajat Ranka, Arjun, Prasan Kumar Panda et al.The need for an antiviral against COVID-19 prompted clinical trials worldwide and based on initial promising trends, remdesivir was widely used, including in India (compassionate use). Subsequent trials have been conflicting in their results and the utility of the drug has been widely debated. This is a record-based retrospective cohort study in a 1000-bedded government teaching hospital in North India. … …American Journal of Pharmacology and Toxicology, Vol. 17, Issue 1 · 3 Jun 2022 · 7,210 accessesView PDFCite
Research ArticleOpen accessIn the abstractCharacteristics and Incidence of Candidemia in Hospitalized Coronavirus 2019 (COVID-19) PatientsNaana A Boachie, Jackie P. Johnston, Simi A. Philip et al.Management of Coronavirus 2019 (COVID-19) with high-dose corticosteroids and interleukin-2 inhibitors has potential benefits, but is associated with immunosuppression and risk of secondary infections. This single-center, retrospective, cohort study evaluated the incidence of candidemia and associated risk factors in hospitalized COVID-19 patients. Twenty-three patients developed candidemia and were matched to 77 non-candidemic COVID-19 controls. The primary outcome was incidence of … …American Journal of Infectious Diseases, Vol. 18, Issue 1 · 18 Jan 2022 · 7,598 accessesView PDFCite
Literature ReviewOpen accessIn the abstractCystatin C as a New Biomarker in Patients with Chronic Kidney Disease a Review and Meta-AnalysisLingxin Bao, Qiaoyan Zhou, Yanfang Lin et al.The objective of this study was to evaluate the correlation between cystatin C (CysC) and patients with Chronic Kidney Disease (CKD). Prospective or retrospective cohort studies which compared the levels of CysC in patients with CKD and healthy controls were searched on PubMed, Contents, CINAHL and EMBASE from 2013 to December 31, 2020. R3.5.2 software was utilized to perform data … …American Journal of Biochemistry and Biotechnology, Vol. 17, Issue 3 · 12 Oct 2021 · 6,568 accessesView PDFCite
EditorialOpen accessIn the abstractAssociation between Infective Endocarditis and Premalignant Colorectal LesionsCarles FalcesThe association between Infective Endocarditis (IE) and Colorectal Cancer (CRC) has been known for more than 50 years. The microorganisms in which this association has been described are Streptococcus gallolyticus (formerly Streptococcus bovis) (Corredoira-Sánchez et al., 2012; Boleij et al., 2011), in different subspecies and, more recently, Enterococcus faecalis (Pericàs et al., 2016; 2017; Escolà-Vergé et al., 2020; Pericàs et … …American Journal of Infectious Diseases, Vol. 17, Issue 3 · 10 Jun 2021 · 11,559 accessesView PDFCite
Research ArticleOpen accessIn the abstractRelationship between Outcomes of COVID19, its Susceptibility and Blood GroupsPalwasha Khan, Hamza Zahid Ullah Muhammadzai, Salman Zahid et al.COVID-19, a viral infection spread across the world affecting many people around the world. In ABO blood type, certain types are more prone to infections and causes severe symptoms. Relationship between ABO blood type and COVID -19 still needs to be found out. A prospective cohort study was conducted to evaluate a relationship between ABO blood type and COVID-19. Data … …American Journal of Infectious Diseases, Vol. 17, Issue 4 · 23 Oct 2021 · 6,436 accessesView PDFCite
Literature ReviewOpen accessIn the abstractDevelopment of Azithromycin Resistance in Streptococcus pneumoniae in the Setting of Trachoma Mass Drug Administration: A Systematic ReviewNazia Khan, Barbara Lachana Onen, Robin Hilder, Robin BaileyTrachoma is a blinding eye disease caused by the bacterium Chlamydia trachomatis. The current global elimination of trachoma initiative includes the use of mass drug distribution of azithromycin in areas where the prevalence of follicular trachoma is >10% in children aged 1-9 years. This study aims to investigate the high quality evidence of whether mass drug administration for trachoma causes … …American Journal of Infectious Diseases, Vol. 16, Issue 3 · 24 Jul 2020 · 7,596 accessesView PDFCite
Research ArticleOpen accessIn the abstractJoint Modelling of Longitudinal-Time-To-Event with Categorical Variable Indicators of Latent Classes: Application to Tuberculosis DataAdeboye Azeez, Mutambayi Ruffin, Ndege James, Qin YongsongIn many clinical and reliability research reports, the outcomes of basic interest is the time to a particular event happens in order to indicate the person’s “true” state of health or survival status. Different models have been used to analyze such data separately, but may be unsuitable if the longitudinal and health status measures are correlated. In this study, mixed … …Journal of Mathematics and Statistics, Vol. 16, Issue 1 · 9 Jun 2020 · 6,686 accessesView PDFCite
Research ArticleOpen accessIn the abstractDirect Acting Anti-Viral Drugs Improve Health-Related Quality of Life in Patients' with Hepatitis CWesam Morad, Warda Othman, Esam Elshimi, Nashwa SheblChronic hepatitis C Virus (HCV) causes significant decline in the Health Related Quality of Life (HRQL). Recently, direct Acting Anti-viral Drugs (DAA) have been endorsed as standard of care for treatment for HCV. To study the HRQL in patients with HCV and cirrhosis before and after DAA. Study design: Prospective cohort hospital based study. We included 500 patients with HCV … …American Journal of Infectious Diseases, Vol. 16, Issue 2 · 29 Apr 2020 · 7,145 accessesView PDFCite
EditorialOpen accessIn the abstractEditorial Commentary: Challenge of Non–AIDS-Defining Cancers (NADCs), Focusing on Trans Activation Response Element (TAR) RNA Embedding ExosomesLechuang Chen, Ge JinGlobally, 37.9 million people were living with HIV at the end of 2018 (Organization, 2018). Cancer is a major cause of mortality and morbidity in AIDS patients and chronically HIV-infected people. With the aid of combination Antiretroviral Therapy (ART), people living with HIV (PLWH) have a longer life span. However, because the virus is not completely eradicated, PLWH under antiretroviral … …American Journal of Immunology, Vol. 15, Issue 1 · 28 Nov 2019 · 6,657 accessesView PDFCite
Research ArticleOpen accessIn the abstractComparing the Diagnostics Accuracy of CD4+ T-Lymphocyte Count and Percent as a Surrogate Markers of Pediatric HIV DiseaseMusie Ghebremichael, Haben Michael, Jack Tubbs, Elijah PaintsilThe percentage CD4+ T-lymphocytes is used to monitor pediatric HIV disease. However, in resource-limited settings, enumerating the percentage of CD4+ T-lymphocytes is hampered by the lack of laboratory infrastructure and trained technicians. In this paper, we investigated the performances of the percentage and absolute CD4+ T-lymphocytes as markers of pediatric HIV disease progression using data from HIV-infected children enrolled through … …Journal of Mathematics and Statistics, Vol. 15, Issue 1 · 3 Apr 2019 · 7,521 accessesView PDFCite