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21 results for “bone marrow”
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Research ArticleOpen accessIn the abstractAssessment of Therapeutic Effects of Platelet-Rich Plasma in Knee Osteoarthritis: Possible Role of Inflammatory CytokinesMohammed H. Hassan, Sawsan Abuhamdah et al.Osteoarthritis (OA) is a multifactorial disease that commonly affects the knee. Tumor Necrosis Factor-α (TNF-α) regulates inflammation during OA. Macrophage Migration Inhibitory Factor (MIF) may be involved in the pathophysiology of arthritis. Platelet-Rich Plasma (PRP) may reduce pain associated with OA. The present study assessed the possible therapeutic effects of PRP in patients with OA of the knee with varying … …American Journal of Biochemistry and Biotechnology, Vol. 17, Issue 2 · 15 Jun 2021 · 6,987 accessesView PDFCite
Research ArticleOpen accessIn the abstractMechanically Stimulated Osteoblast Cells GrowthRaffaella Aversa, Antonio Apicella, Francesco Tamburrino, Florian Ion Tiberiu PetrescuThe bones need to be built and then permanently restored to keep them functioning properly. Considering the multiple bone functions, their vitality is essential both to maintain the body and move it and to maintain its health and vigor. When most bones begin to age and have no vital function, the man also begins to age, lose water, minerals, electrolytes, … …American Journal of Engineering and Applied Sciences, Vol. 11, Issue 2 · 19 Jun 2018 · 7,882 accessesView PDFCite
Research ArticleOpen accessIn the abstractAbout the Internal Structure of a Bone and its Functional RoleAntonio Apicella, Raffaella Aversa, Francesco Tamburrino, Florian Ion Tiberiu PetrescuThe human skeleton has the primary role of supporting all the organs that make up the body and at the same time to protect them permanently. It is made up so that it can hold and hold together all internal human organs, protecting them permanently, but also allowing them to move and exercise all their functionalities. This paper wants to … …American Journal of Engineering and Applied Sciences, Vol. 11, Issue 2 · 26 May 2018 · 8,402 accessesView PDFCite
Review ArticleOpen accessIn the abstractThe Triple Immune Argument; Surveillance/Evasion/ Senescence and the Increased Incidence of Acute Myeloid Leukemia Observed with AgeManar M. IsmailAML originates from genetic insults of hematopoietic stem and progenitor cells (HSPCs/HSCs) that was identified earlier as leukemia stem cells (LSCs). In quiescent state, trafficking immune cells are crucial for eradication of aberrant clones and obtaining balance between proliferation and apoptosis to maintain HSCs pool. Regulatory T-cells shield the HSCs from the inflammatory reactions by suppressing T- and B- cells. … …American Journal of Immunology, Vol. 13, Issue 4 · 22 Dec 2017 · 7,806 accessesView PDFCite
Research ArticleOpen accessIn the abstractβ-Glucan in AllergiesSima Petr, Vetvicka VaclavMultiple effects of β-glucan are well established. Together with the effects on antibacterial and anticancer immunity, glucan has been shown to stimulate bone marrow cells, lower cholesterol and to protects against stress and some kinds of poisoning. However, despite literally thousands of papers describing biological effects of β-glucan, only limited attention has been focused on the role of β-glucan in … …American Journal of Immunology, Vol. 13, Issue 1 · 30 Mar 2017 · 8,981 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffects of Unilateral Cervical Vagotomy on Murine Dendritic CellsDaniel Sanzio Gimenes da Cruz, Ana Paula Nascimento de Lima, Patrícia Benites Gonçalves da Silva et al.The cholinergic anti-inflammatory pathway has been demonstrated to be an important mechanism that modulates several inflammatory diseases. This modulation occurs upon activation of the vagus nerve, which modulates splenic macrophages and lymphocytes through the predominant neurotransmitter, Acetylcholine (ACh). We hypothesized that this modulation could also take place in dendritic cells, as these cells represent a link between the innate and … …American Journal of Immunology, Vol. 11, Issue 2 · 12 Jul 2015 · 6,948 accessesView PDFCite
Research ArticleOpen accessIn the abstractMesenchymal Stem Cell Transplantation for Retinal Degenerations and Dystrophies: Present and FutureEmma Ghazaryan, Shurong Wang, Yan Zhang et al.Retinal degenerations are the main causes of irreversible blindness in developed countries. Up to date the main pathological mechanisms of these diseases are not fully understood and consequently there is no complete treatment option for those diseases. In this aspect stem cells have drawn attention of many researchers and health care professionals. Considering ethical issues, safety and facile isolation Mesenchymal … …American Journal of Biochemistry and Biotechnology, Vol. 10, Issue 4 · 28 Nov 2014 · 6,766 accessesView PDFCite
Research ArticleOpen accessIn the abstractAntioxidant and Antimutagenic Activities of Taif Grape (Vitis vinifera) CultivarsAbdelmegid Ibrahim Fahmi, Mohamed Ahmed Nagaty, Ahmed Mohamed El-ShehawiExtract of grape Vitis vinifera has been reported to exhibit antioxidant and antimutagenic activities and the phenolic compounds play a vital role in determining these activities. Therefore; the objective of the present study was to evaluate the antioxidant and anti-mutagenic activities as well as the phenolic composition of different grape cultivar extracts collected from Taif region. The grape cultivars namely; … …American Journal of Biochemistry and Biotechnology, Vol. 9, Issue 2 · 20 Jun 2013 · 8,010 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffect of Storing Temperature on Hepatotoxicity and Nephrotoxicity of Ifosfamide in Female RatFalah Mohammed AzizProblem statement: Ifosfamide (IFO) is a cytotoxic alkylating drug used for the treatment of a variety of cancers, although it has been found to induce certain hematological, hepatotoxic and nephrotoxic side effects. This drug is widely used in developing country, especially Iraq, but without caring too much to the storing temperature due to low drug maintaining facilities. The present work … …OnLine Journal of Biological Sciences, Vol. 12, Issue 1 · 19 Mar 2012 · 7,883 accessesView PDFCite
Research ArticleOpen accessIn the abstractEvaluation of Immunomodulatory Effect: Selection of the Correct Targets for Immunostimulation StudySwee Keong Yeap, Mashitoh Binti Abd Rahman, Noorjahan Banu Alitheen et al.Problem statement: Numerous plants or remedies that are traditionally used for various diseases had been claimed to maintain general good health, particularly the immune system. With the advanced understanding on immunology and ethnopharmacology, study on the interaction of this herb with the immune system is critical to understand the safety and its efficacy as a potent immunomodulatory agent. Approach: Selecting … …American Journal of Immunology, Vol. 7, Issue 2 · 4 Nov 2011 · 10,736 accessesView PDFCite