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45 articles for “bioactive compounds”

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Review ArticleOpen accessIn the keywordsBioactive Functional Foods for Cardiovascular DiseasesKiren Mustafa, Iqra Ajmal, Tahira Naz et al.Cardiovascular Disease (CVD) is a chronic pathological disorder regarded as a serious health concern round the globe. It is a multifactorial disease, with a range of various causative agents, among that dietary factor is considered the most important and may to a large degree determine CVD risk. Unfortunately, it has been less widely investigated. This review outlines the general aspects … …American Journal of Biochemistry and Biotechnology, Vol. 16, Issue 3 · 17 Aug 2020 · 7,831 accessesView PDFCite
Research ArticleOpen accessIn the abstractMarine-Derived Extracts as Economically Sustainable and Ethical Alternatives to Fetal Bovine Serum in HEK293 Cell CultureKian Kenneth Francisco Sanchez, Jennifer Seki-Wong et al.Fetal Bovine Serum (FBS) is a staple supplement in cell culture, providing key growth factors that promote cell health and proliferation. Since 1885, cell culture has been a cornerstone of both basic and applied research, leading to significant discoveries of cell communication and function. However, the use of FBS presents economic and ethical challenges. Millions of bovine fetuses are euthanized … …American Journal of Biochemistry and Biotechnology, Vol. 22, Issue 3 · 7 Aug 2026 · 1,042 accessesView PDFCite
Research ArticleOpen accessIn the abstractFirst Morphoanatomical and Cytogenetic Characterization of Picria fel-terrae Lour.: A Local Accession from Dairi Regency, IndonesiaElimasni, Deny Supriharti, HaryatiPoguntano (Picria fel-terrae Lour.) plant has been widely recognized for its medicinal properties due to its bioactive compounds. However, fundamental biological studies, particularly on its phenological and cytogenetic characteristics, remain limited. This study aimed to characterize the vegetative morphology and karyotypic features of P. fel-terrae from Dairi Regency, North Sumatra, to provide a comprehensive cytogenetic database for future study and … …OnLine Journal of Biological Sciences, Vol. 26, Issue 2 · 17 Jul 2026 · 745 accessesView PDFCite
Research ArticleOpen accessIn the abstractIntegrated Monitoring of Endocrine-Disrupting Chemicals: Analytical Chemistry and Biological Assessment ApproachesChangjin Li, Jing Huo, Zijun Dou et al.Endocrine-Disrupting Chemicals (EDCs) in aquatic environments pose significant threats to ecosystems and human health. These compounds interfere with hormonal regulation at low concentrations and have non-monotonic dose-response relationships, posing challenges to conventional risk assessment. This review systematically compares current EDC monitoring methods, including instrumental chemical analysis and receptor-based biological detection systems, to evaluate sensitivity thresholds, sample throughput, and mechanistic selectivity … …American Journal of Biochemistry and Biotechnology, Vol. 22, Issue 2 · 3 Jul 2026 · 1,081 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffects of a Cyclachaena Xanthiifolia Extract on Trematodes Opisthorchis Felineus: An in Vitro StudyDenis Ponomarev, Elena Khramova, Natalia Gubanova et al.Cyclachaena xanthiifolia is a phytochemically rich invasive weed with documented allelopathic properties, making it a candidate source of bioactive compounds with potential medicinal applications. This study investigated the anthelmintic activity of a crude aqueous-ethanolic extract of C. xanthiifolia (CxEt), prepared from equal proportions of leaves and seeds, against the trematode Opisthorchis felineus in vitro. The effects of CxEt on the … …OnLine Journal of Biological Sciences, Vol. 26, Issue 2 · 1 Jun 2026 · 1,251 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffect of Phytobiotic Carica Papaya Seed Extract on Growth Performance, Physiological Parameters, Gastrointestinal and Immune Organs of BroilersNovi Mayasari, Erna Ainal Mardiah, Selly Masella et al.Papaya (Carica papaya) seeds (PS) are known as a potential phytobiotic alternative to Antibiotic Growth Promotor (AGP) in poultry. Papaya seed extract (PSE) contains bioactive compounds such as carpine, chymopapain, and papain. Two hundred one-day-old Cobb strain broiler chicks were randomly allocated to five dietary treatments with four replicates per treatment, and each replicate consisted of ten birds. During the … …American Journal of Animal and Veterinary Sciences, Vol. 21, Issue 1 · 13 Apr 2026 · 1,900 accessesView PDFCite
Research ArticleOpen accessIn the abstractMolecular Identification and Antioxidant Profiling of Penicillium heteringtonii EUA-017 from Mangrove (Avicennia alba) in West Sumatra, IndonesiaAnthoni Agustien, Djong Hon Tjong, Yetria Rilda et al.Mangrove ecosystems harbor diverse endophytic fungi that produce bioactive secondary metabolites with potential antioxidant activities. This study aimed to identify an endophytic fungal isolate (EUA-017) from Avicennia alba mangroves in West Sumatra, Indonesia, and characterize its antioxidant metabolites. Molecular identification was performed using internal transcribed spacer (ITS) region sequencing. Secondary metabolites from ethyl acetate extracts were characterized using Fourier-transform infrared … …OnLine Journal of Biological Sciences, Vol. 25, Issue 4 · 25 Mar 2026 · 1,410 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffects of Different Extraction Methods on the Quality of Peony Seed Oil and Its Emulsion PropertiesKang Li, Chao Du, Shuxian Pang et al.Peony seed oil, as a functional oil rich in ω-3 polyunsaturated fatty acids and natural antioxidant components, has its extraction process directly affecting the maintenance of bioactive substances and the added value of the product. In this analysis, the effects of wet milling-micronized continuous leaching method (MCI), solvent extraction (SE), soxhlet extraction (SOXE) and ethanol-assisted enzymatic hydrolysis (EAH) on the … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 3 · 28 Jan 2026 · 1,955 accessesView PDFCite
Research ArticleOpen accessIn the abstractBioactivity of Sumac (Rhus Coriaria) Extract as a Green Alternative for Plant Pathogen InhibitionMohammed H. Al-Mamoori, Meisam Zargar, Elena N. Pakina, Fatih DadaşoğluEnvironmental stress caused by pathogenic fungi leads to considerable losses in global crop productivity. Plant-derived extracts are eco-friendly and sustainable alternatives that can inhibit biotic stresses. Sumac (Rhus coriaria) is widely used in industrial and medicinal applications due to its extract rich in secondary metabolites, similar to those found in chemical pesticides and pharmaceuticals. This study aimed to characterize the … …OnLine Journal of Biological Sciences, Vol. 25, Issue 3 · 25 Nov 2025 · 2,209 accessesView PDFCite
Research ArticleOpen accessIn the abstractUPLC-Q-Exactive Orbitrap-MS Analysis of Anchusa italica Retz. Flowers: Molecular Docking, Dynamics Modeling, and Pharmacokinetics for Cardiovascular DiseaseLinyang Wang, Yan Chen, Ainiwaer Aikemu, Shuge TianThis study builds on prior UPLC-Q-Exactive Orbit rap-MS analyses of Anchusa italica Retz. Flowers (Airfs) to explore their anti-cardiovascular mechanis·ms and key bioactive markers. UPLC-Q-Exactive Orbitrap-MS identified 30 major compounds, including polyphenols and flavonoids with strong antioxidant activity. The potential active ingredients were then screened using Lipinski's rule of five, and a network pharmacology method was employed to construct an … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 2 · 25 Oct 2025 · 2,599 accessesView PDFCite