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38 results for “antiretroviral”
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EditorialOpen accessIn the abstractEditorial Commentary: Challenge of Non–AIDS-Defining Cancers (NADCs), Focusing on Trans Activation Response Element (TAR) RNA Embedding ExosomesLechuang Chen, Ge JinGlobally, 37.9 million people were living with HIV at the end of 2018 (Organization, 2018). Cancer is a major cause of mortality and morbidity in AIDS patients and chronically HIV-infected people. With the aid of combination Antiretroviral Therapy (ART), people living with HIV (PLWH) have a longer life span. However, because the virus is not completely eradicated, PLWH under antiretroviral … …American Journal of Immunology, Vol. 15, Issue 1 · 28 Nov 2019 · 6,662 accessesView PDFCite
Case ReportOpen accessIn the abstractLeprosy in a Patient Coinfected with HIV and SyphilisCarla Andréa Avelar Pires, Julius Caesar Mendes Soares, Maria Amélia Lopes dos Santos et al.Case report of a male patient, fifty years old, born in the Amazon region of Belém, Pará, northern Brazil. He was attended at a University service of reference in Dermatology on 09/14/2018, referring to "ball injuries" about a year ago with a sudden and progressive appearance in the abdomen with dissemination to the whole body. Three months ago he was … …American Journal of Infectious Diseases, Vol. 15, Issue 2 · 29 Jul 2019 · 7,290 accessesView PDFCite
Research ArticleOpen accessIn the abstractClinical and Epidemiological Characteristics of New Cases of HIV/AIDS Identified between 2011-2016 at a Tertiary Hospital, in Mexico CityEnrique Alcalá Martínez, Verónica Alejandra Gaona Flores, Paz Ayar Nibardo, Guevara Iturriaga SamantaNowadays, HIV infections and AIDS cases are on the increase in Africa, Asia, Latin America and the Caribbean. The associated risk factors for developing AIDS have been: Alcoholism, drug use, malnutrition, comorbidities and semi-illiteracy. The objective of the study was to describe the clinical and epidemiological characteristics of new cases of HIV/AIDS and to look for the possible factors associated … …American Journal of Infectious Diseases, Vol. 14, Issue 2 · 5 Sep 2018 · 7,920 accessesView PDFCite
Research ArticleOpen accessIn the abstractCryptococcosis Neuro-Brain in 42 Patients at the University Hospital of BrazzavilleOssibi Ibara Bienvenu Rolland, Mabiala Babela Jean Robert, Attinsounon Cossi Angelo et al.To describe epidemiological, clinical, therapeutic; and evolutionary aspects of Neuromeningeal Cryptococcus (NMC) at Brazzaville University Hospital and to find out factors associated to death. A descriptive and analytical retrospective study of NMC files in the infectious diseases department between January 1 and December 31, 2013. 973 patients were hospitalized, 42 NMC cases (4.3%) were compiled. The mean age was 40.2±10.4 … …American Journal of Infectious Diseases, Vol. 13, Issue 4 · 2 Mar 2018 · 7,411 accessesView PDFCite
Research ArticleOpen accessIn the abstractNevirapine Hepatotoxicity: Implications of Risk FactorsElias Adikwu, Oputiri Deo, Oru-Bo Precious Geoffrey, D. Akuegbe EnimeyaHighly active antiretroviral therapy is used in the management of HIV/AIDS; it has contributed tremendously in the reduction of mortality and morbidity rate in HIV patients. Despite the outstanding achievement with the use of HAART its major limitation is toxicity. Among these toxicities is hepatotoxicity which is said to be associated with nevirapine containing highly active antiretroviral therapy. Recent reports … …American Journal of Pharmacology and Toxicology, Vol. 8, Issue 2 · 3 Jun 2013 · 7,655 accessesView PDFCite
Research ArticleOpen accessIn the abstractIn-Depth Review of Human Immunodeficiency Virus-Associated NephropathySira Korpaisarn, Wisit Cheungpasitporn, Daych Chongnarungsin et al.Human Immunodeficiency Virus (HIV)-Associated Nephropathy (HIVAN) is one of the most important renal complications found in HIV-infected individuals. Morbidity and mortality in this group of patients increases due to End-Stage Renal Disease (ESRD). Classic histological characteristics of HIVAN are collapsing Focal Segmental Glomerulosclerosis (FSGS), microcystic tubular dilation and interstitial inflammation and fibrosis. High prevalence of HIVAN among people of African … …Current Research in Medicine, Vol. 4, Issue 1 · 19 Apr 2013 · 7,366 accessesView PDFCite
Research ArticleOpen accessIn the abstractConcentration-Effect, Incidence and Mechanism of Nevirapine HepatotoxicityAdikwu Elias, Brambaifa NelsonNevirapine is a dipyridozepinone non nucleoside reverse transcriptase inhibitor approved for use in HIV-infected patients. Its efficacy has been well demonstrated in numerous clinical trials. It has activity against HIV-1 but does not have significant activity against HIV-2 or other retroviruses. Nevirapine is used as one of the components of highly active antiretroviral therapy in HIV patients and in the … …American Journal of Pharmacology and Toxicology, Vol. 8, Issue 1 · 19 Apr 2013 · 8,161 accessesView PDFCite
Research ArticleOpen accessIn the abstractFrequency of P/S(XX)P Duplication and FRFE, Absence of LYP in P6Gag of Indian Human Immunodeficiency Virus-1 Subtype C IsolatesKrutika Wadekar, Sudhanshu Pandey, Preeti Jain et al.Problem statement: The presence of a p6 domain at the C-terminus of the Gag polyprotein is a characteristic feature of HIV-1 and other primate lentiviruses. The p6Gag protein is considered as a major phosphoprotein in mature HIV-1 virions and is involved in the viral assembly and budding process. Sequence variation in the p6gag region in HIV-1 has been associated with … …Current Research in Medicine, Vol. 1, Issue 2 · 31 Oct 2010 · 7,531 accessesView PDFCite
Research ArticleOpen accessIn the abstractRole of Hematological and Alternate Markers in Human Immunodeficiency Virus Disease ProgressionK. V. Ramana, Jagadeeshwara Chary, V. Sabitha et al.Problem statement: The knowledge of HIV infection has expanded tremendously which has led to significant improvement in the treatment, leading to decrease in morbidity and mortality. Considering the limitations in using CD4+T-cell counts and HIV RNA viral load as markers in the HIV disease progression, physicians treating the HIV patients now look for alternate markers that predict HIV disease progression … …Current Research in Medicine, Vol. 1, Issue 2 · 31 Oct 2010 · 7,375 accessesView PDFCite
Research ArticleOpen accessIn the abstractAbnormal Glucose Regulation and Treatment Strategies for Insulin Resistance HIV-Infected PatientsSteven GrinspoonHIV-infected patients receiving highly active antiretroviral therapy often demonstrate abnormalities in glucose regulation, in association with changes in fat distribution[1,2]. In the majority of cases, these abnormalities are best characterized by insulin resistance and impaired glucose tolerance, rather than overt diabetes mellitus and fasting hyperglycemia. Insulin resistance may result from direct effects of antiretroviral therapy, changes in fat distribution or … …American Journal of Infectious Diseases, Vol. 2, Issue 3 · 30 Sep 2006 · 6,391 accessesView PDFCite