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54 results for “adaptive response”
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EditorialOpen accessIn the abstractFocalize the Structure of Myd88 in TLR Signaling Pathway to Modulate Innate Immune Response: New Target for Old DiseasesShuai Xing, Ping ZhouAll diseases have their Achilles’ Heel to target and this is especially true for immunorelated diseases which must be treated by targeting the immune system somewhere and somehow correctly. In the most recent decade, immunologists recognized that the Toll-Like Receptor (TLR) signaling pathway in innate immune system plays a double-edged role in the pathogenesis of many notorious diseases. Although the … …American Journal of Immunology, Vol. 13, Issue 3 · 6 Sep 2017 · 7,862 accessesView PDFCite
Research ArticleOpen accessIn the abstractEvaluation of Alternative Cropping and Nutrient Management Systems with Soil and Water Assessment Tool for the Raccoon River Watershed Master PlanPhilip Gassman, Manoj Jha, Calvin Wolter, Keith SchillingThe Soil and Water Assessment Tool (SWAT) ecohydrological model was used to assess a suite of adaptive nutrient management, alternative cropping system and combination scenarios in support of a Master Plan that was developed to help guide policy makers, land owners and other stakeholders in improving water quality for the 9,400 km2 Raccoon River watershed in west central Iowa, located … …American Journal of Environmental Sciences, Vol. 11, Issue 4 · 9 Sep 2015 · 7,612 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffects of Unilateral Cervical Vagotomy on Murine Dendritic CellsDaniel Sanzio Gimenes da Cruz, Ana Paula Nascimento de Lima, Patrícia Benites Gonçalves da Silva et al.The cholinergic anti-inflammatory pathway has been demonstrated to be an important mechanism that modulates several inflammatory diseases. This modulation occurs upon activation of the vagus nerve, which modulates splenic macrophages and lymphocytes through the predominant neurotransmitter, Acetylcholine (ACh). We hypothesized that this modulation could also take place in dendritic cells, as these cells represent a link between the innate and … …American Journal of Immunology, Vol. 11, Issue 2 · 12 Jul 2015 · 6,948 accessesView PDFCite
Research ArticleOpen accessIn the abstractDialectic Form Finding of Structurally Integrated Adaptive StructuresL. Rhode-Barbarigos, V. Charpentier, S. Adriaenssens, O. BaverelStructural engineering, prompted by advances in mechanics and computing as well as design principles such as sustainability and resilience, is evolving towards adaptive structures. Adaptive structures are structures that use active components to change shape and properties in response to their environment and/or to their users' desires. Form-found structures, such as tensegrity and shell structures, can be designed to accommodate … …American Journal of Engineering and Applied Sciences, Vol. 8, Issue 4 · 6 Jul 2015 · 7,850 accessesView PDFCite
EditorialOpen accessIn the abstractImpact of Quantitative Pharmacology on Drug DevelopmentAna Ruiz-Garcia, Kourosh ParivarThesuccess of drug development rests over two well defined pillars, a goodunderstanding of the drug’s clinical pharmacology and the appropriate targetpopulation for whom the clinical use is intended. The label for human prescription drugsrequires a good understanding of the pharmacological effects (pharmacodynamicsor PD) and the mechanism of action of the drug as well as detailed informationof the drug’s Pharmacokinetics (PK): … …American Journal of Pharmacology and Toxicology, Vol. 9, Issue 4 · 24 Apr 2015 · 7,158 accessesView PDFCite
Research ArticleOpen accessIn the abstractImmunological Processes in Cancer: A Link Between Inflammation and ImmunityVanessa Jacob Victorino, Isabela Casagrande Jeremias, Anne Karine Martins AssunçãoCancer is a worldwide issue and one of the most relevant death causes in child and adults. There are several causes that can lead to cancer development. It is well known that inflammation is one known hallmark of cancer and it favors tumor cells growth. Several alterations in immunological and inflammatory processes are caused in response to tumor presence and … …American Journal of Immunology, Vol. 10, Issue 4 · 17 Jan 2015 · 7,073 accessesView PDFCite
EditorialOpen accessIn the abstractRECENT TRENDS AND CHALLENGES OF ENERGY EFFICIENT AND SUSTAINABLE BUILDINGSChiara BedonAccording to several studies (e.g., the Intergovernmental Panel on Climate Change (IPCC, 2014), the US Energy Information Administration (US EIA, 2014), warming of the climate system is unequivocal and mainly derives from greenhouse gas emissions due to human activities. Global Carbon Dioxide (CO2) emissions from fossil fuels, for example, are estimated to be 29% higher in 2035 than they were … …American Journal of Engineering and Applied Sciences, Vol. 7, Issue 3 · 11 Sep 2014 · 8,497 accessesView PDFCite
Research ArticleOpen accessIn the abstractCLASSIFICATION OF DIGITAL IMAGES USING FUSION ELEVATED ORDER CLASSIFIER IN WAVELET NEURAL NETWORKR. Arulmurugan, P. SengottuvelanThe revival of wavelet neural networks obtained an extensive use in digital image processing. The shape representation, classification and detection play a very important role in the image analysis. Boosted Greedy Sparse Linear Discriminate Analysis (BGSLDA) trains the cascade level of detection in an efficient manner. With the application of reweighting concept and deployment of class-reparability criterion, lesser search was … …Journal of Computer Science, Vol. 10, Issue 9 · 23 Jun 2014 · 6,790 accessesView PDFCite