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20 results for “Utoh-Nedosa”
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Research ArticleOpen accessIn the author namesStimulatory Effects of Dihydroartemisinin on the Leucocyte Population of Wistar Albino RatsU. A. Utoh-Nedosa, P. A. Akah, C. O. Okoli et al.Problem statement: Five dosages of Dihydroartemisinin (DHA) which included 1 mg kg-1; a repeated dose of 1; 2; 60 and 80 mg kg-1 were administered orally to albino rats for 5 days. The results of the study showed that dihydroartemisinin treatment significantly elevated the total white cell count (p<0.01); the percentage neutrophil count (p<0.01) and the percentage lymphocyte count (p<0.05). … …American Journal of Infectious Diseases, Vol. 7, Issue 3 · 17 Nov 2011 · 7,350 accessesView PDFCite
Research ArticleOpen accessIn the author namesSlow Fungal Hydrolysis of Complex Sugar is Responsible for the Use of Sugar as Vehicle for Antifungal DrugsNedosa Ikenna Valentine, Utoh-Nedosa Uchechukwu Anastasia, Dan Danjuma et al.Problem statement: Aspergillus niger strain (UUF 9202) significantly reduced the dormancy period and boosted aggregate germination time in seeds of Tetrapleura tetraptera by 42% in 32 days and produced a net reduction in mean germination time of the seeds to 12 days. A structure-fungitoxicity relationship study of a series of isoflavonoids against Aspergillus niger and Cladosporium cucumerinum showed that a … …American Journal of Pharmacology and Toxicology, Vol. 6, Issue 3 · 2 Nov 2011 · 7,665 accessesView PDFCite
Research ArticleOpen accessIn the author namesCell Surface Receptor Theory of Disease Infectivity; Body's Defence and Normal Body Functioning in Living ThingsUtoh-Nedosa, Uchechukwu AnastasiaProblem statement: A study of the pattern of Candida spp. infection of the human body and the mode and pattern of reaction of the human body to this infection showed that disease infectivity and self healing by plants followed the same procedures and patterns. Approach: A comparism of these procedures and patterns of natural self- healing of disease infection by … …OnLine Journal of Biological Sciences, Vol. 11, Issue 2 · 26 Oct 2011 · 7,240 accessesView PDFCite
Research ArticleOpen accessIn the author namesMechanisms of Anti-Cancer Effects of Vernonia amygdalina Leaf ExtractUtoh-Nedosa Uchechukwu AnastasiaProblem statement: Vernonia amygdalina (V. amygdalina) has been shown to have cancer cell inhibition and cytotoxic effects. Approach: This study discusses the multi-faceted and multi-linked mechanisms by which cancer tissue inhibition and destruction is achieved by V. amygdalina leaf extract and powder (subsequently called V. amygdalina Extract). Cancer cell inhibition by V. amygdalina is suggested to occur through inhibition of … …American Journal of Pharmacology and Toxicology, Vol. 6, Issue 3 · 26 Oct 2011 · 9,090 accessesView PDFCite
Research ArticleOpen accessIn the author namesThe Body Calming and Body Vitalizing Effects of Vernonia Amygdalina Leaf Extract and Leaf Powder and their MechanismsUtoh-Nedosa Uchechukwu AnastasiaProblem statement: Vernonia amygdalina (V. amygdalina) leaf soup is regarded by the indigenous Igbo people of South Eastern Nigeria as their best leafy vegetable soup. Despite the bitterness of the bitter leaf soup, the native eaters of the soup feel very content when they eat pounded carbohydrate foods with it. Oral V. amygdalina leaf extract was taken methodically in this … …American Journal of Agricultural and Biological Sciences, Vol. 6, Issue 3 · 20 Sep 2011 · 8,163 accessesView PDFCite
Research ArticleOpen accessIn the author namesExcess Body Fat Elimination (Anti-Obesity) Effects of Vernonia Amygdalina Leaf ExtractUtoh-Nedosa Uchechukwu Anastasia, Anowi Chinedu Fred, Nedosa Kenechi Stanislaus, Oduche Uzoamaka AnthoniaProblem statement: Many obese or overweight persons complain that they don’t know what makes them fat. They would also like to know how to loss excess fat and maintain the fat loss. Approach: This research study was structured to make the obesed subject loose excess fat and at the same time learn what makes people fat so that in the … …American Journal of Pharmacology and Toxicology, Vol. 6, Issue 2 · 17 Aug 2011 · 8,524 accessesView PDFCite
Research ArticleOpen accessIn the author namesRespiratory Tract-Widening Effects of Dihydroartemisinin in Wistar Albino RatsUtoh-Nedosa Uchechukwu, Njoku Goddy, S. Nedosa Kenechi et al.Problem statement: Artemisinin-based anti-malarials are currently widely used in Asia and Africa. Not much is known about the systemic effect of dihydroartemisinin. This study therefore examine the effect of dihydroartemisinin on the lungs of Wistar albino rats. Approach: Five dosages of Dihydroartemisinin (DHA) were administered by oral intubation for 5 days to 5 test and 4 control Wistar albino rats. … …American Journal of Pharmacology and Toxicology, Vol. 6, Issue 2 · 17 Aug 2011 · 7,515 accessesView PDFCite
Research ArticleOpen accessIn the author namesInhibition of Skin Colour Darkening (Skin Clearing and Lightening); Skin Firming; Body Calming and Body Vitalizing Effects of Vernonia amygdalina Leaf ExtractUtoh-Nedosa Uchechukwu AnastasiaProblem statement: Obese human subjects treated with oral Vernonia amygdalina (V. amygdalina) aqueous leaf extract for one month who experienced the anti-obesity effects of V. amygdalina leaf extract reported a lighter; clearer; more glowing and firmer skin as side effects of the treatment (unpublished findings). In this study, oral Vernonia amygdalina aqueous leaf extract was taken daily for six months … …American Journal of Pharmacology and Toxicology, Vol. 6, Issue 2 · 17 Aug 2011 · 8,259 accessesView PDFCite
Research ArticleOpen accessIn the author namesAnti-Carcinoma, Anti-Obesity, Antidiabetic and Immune Defence Effects of Vernonia amygdalina Leaf Extract and Leaf Powder, in Two Human Cancer PatientsUtoh-Nedosa Uchechukwu AnastasiaProblem statement: Two cancer patients were treated with Vernonia amygdalina (V. amygdalina) leaf extract and leaf powder. The leaf extract of V amygdalina was administered orally for 9 months to the first patient in response to his reception of a medical diagnosis of having traces of prostate cancer. Approach: This patient was also over weight by 40 kg. The V. … …American Journal of Immunology, Vol. 6, Issue 4 · 5 Aug 2011 · 8,616 accessesView PDFCite
Research ArticleOpen accessIn the author namesEvaluation of the Toxic Effects of Dihydroartemisinin on the Vital Organs of Wistar Albino RatsA. U. Utoh-Nedosa, P. A. Akah, T. C. Okoye, C. O. OkoliProblem statement: The current surge in the use of Artemisinin based Combination Therapy (ACT) in the treatment of falciparium resistant malaria in the tropics and the potentials of Dihydroartemisinin (DHA), a member of the artemisinin family, to produce toxic effect in the vital organs (such as the liver, heart, lungs, intestine, spleen kidney and blood cells) necessitated this research. Approach: … …American Journal of Pharmacology and Toxicology, Vol. 4, Issue 4 · 31 Dec 2009 · 9,181 accessesView PDFCite