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26 results for “Threshold Effects”

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Research ArticleOpen accessIn the abstractEffects of Playing Surface and Shoe Type on ACL Tears in Soccer PlayersMelissa M. Mansfield, Ronald B. BucinellToday, Anterior Cruciate Ligament (ACL) tears are one of the most prevalent knee injuries, with the occurrence of ACL tears increasing drastically from approximately 80 000 in 2000 to 150 000 in 2011. Although there are many factors that contribute to an ACL tear occurring, certain environmental factors could contribute to the dramatic increase over the past couple decades, especially … …American Journal of Engineering and Applied Sciences, Vol. 9, Issue 4 · 15 Dec 2016 · 12,888 accessesView PDFCite
EditorialOpen accessIn the abstractAre we Able to Harness the Immunomodulatory Power of Cytokines for Novel Autoimmune Disease Treatments?Giuseppe Nocentini, Graziella Migliorati, Carlo RiccardiSince the end of the 1970s, interleukin 2 (IL-2) has been known as a key player in T cell expansion/activation (Watson et al., 1980). In the late 1980s, some groups used IL-2 to stimulate the immune systems of tumour patients (Jacobs et al., 1986). The idea seemed brilliant and several attempts were made, but the results were disappointing (Lim et … …American Journal of Pharmacology and Toxicology, Vol. 10, Issue 2 · 22 Oct 2015 · 7,625 accessesView PDFCite
Research ArticleOpen accessIn the abstractComputer Machine Vision Inspection on Printed Circuit Boards Flux DefectsAng TeohOng, Zulkifilie Bin Ibrahim, Suzaimah RamliThe new visual inspection systems techniques using real time machine vision replace the human visual manual inspection on PCB flux defects, which brings harmful effects on the board which may come in the form of corrosion and can cause harm to the assembly. In short, it brings improvement in Printed Circuit Boards (PCB) production quality, principally concerning the acceptance or … …American Journal of Engineering and Applied Sciences, Vol. 6, Issue 3 · 28 Aug 2013 · 7,955 accessesView PDFCite
Research ArticleOpen accessIn the abstractSafety Health Impacts of Particulate Matter from Excavation Work SitesGiuseppe Pizzo, Marina ClericoEpidemiological studies have shown a linear relationship between airborne particulates and effects on human health. This study examines the risk that can be run by populations which are exposed to significant pollutant sources such as excavation in urban areas for renovation work. The health risk assessment methodology defined by the WHO air quality guidelines for Europe was applied to assess … …American Journal of Environmental Sciences, Vol. 8, Issue 4 · 25 Jul 2012 · 7,933 accessesView PDFCite
Research ArticleOpen accessIn the abstractAnticonvulsant Effect of Pitavastatin in Mice Induced by PentylenetetrazoleKhayatnouri MirhadiProblem statement: The 3-Hydroxy-3-Methylglutaryl-CoA (HMG-CoA) reductase inhibitors (statins) have been unequivocally shown to reduce cardiovascular morbidity and mortality by their lipid-lowering actions. It has been suggested that statins appear to have therapeutic benefits in diseases that are unrelated to elevated serum cholesterol levels. The aim of this study was to evaluation the effect of intraperitoneally injection of different doses of … …American Journal of Animal and Veterinary Sciences, Vol. 6, Issue 4 · 11 Jan 2012 · 7,507 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffect of Phenylbutazone on Pentylenetetrazole-Induced Seizure in MiceKhayatnouri MirhadiProblem statement: The Cyclooxygenases (COXs), the key enzymes that convert arachidonic acid to Prostaglandins (PGs), had been implicated in physiological and pathophysiological functions in the CNS. Non-Stesoidal Anti-Inflammatory Drugs (NSAIDs), COX inhibitors, were used largely to treat febrile condition, pain state and for prevention of and therapeutics of many diseases. However the role of PGs and NSAIDs in the seizure … …American Journal of Animal and Veterinary Sciences, Vol. 6, Issue 4 · 13 Dec 2011 · 7,675 accessesView PDFCite
Research ArticleOpen accessIn the abstractUncommon Toxicologic Profile at Toxic Doses of CPI-613 (an Agent Selectively Alters Tumor Energy Metabolism) in Rats and Minipigs Reflects Novel MechanismClaudia Maturo, King C. Lee, Robert Rodriguez, Robert ShorrProblem statement: CPI-613 is a novel anticancer agent and the toxicological profile has not been assessed. Accordingly, the objective of these studies was to thoroughly evaluate the Toxicokinetic (TK) effects of CPI-613 in rats and to compare the toxicological profile of rats to minipigs to determine if there were differences between the two animal species. Approach: These studies involved assessments … …American Journal of Pharmacology and Toxicology, Vol. 5, Issue 4 · 13 Jun 2011 · 9,582 accessesView PDFCite
Research ArticleOpen accessIn the abstractTurbo-coding of Coherence Multiplexed Optical PPM CDMA System With Balanced DetectionK. Chitra, V.C. RavichandranThe effects of turbo-coding on the coherence multiplexed optical PPM CDMA systems are shown by evaluating bit error rate (BER) with respect to system parameters such as interleaver length (K), number of simultaneous users (N), code length (f), initial pulsewidth (t0) and normalized threshold (θ) by including the effects of thermal noise and shot noise. Turbo-codes increase the number of … …American Journal of Applied Sciences, Vol. 4, Issue 5 · 31 May 2007 · 6,617 accessesView PDFCite
Research ArticleOpen accessIn the abstractStochastic Prognostic Paradigm for Petrochemical Pipelines Subject to FatigueAbdo Abou Jaoude, Khaled El-TawilThe most important aim for industrialists is the prevention and the evaluation of their products state since non-predicted failure is very expensive in some cases. This can be done mainly by the evaluation of the &#34Remaining Useful Lifetime&#34 (RUL) by the means of prognostic approaches compensating the inconveniences of classical maintenance strategies. A proposed analytic prognostic methodology based on damage … …American Journal of Engineering and Applied Sciences, Vol. 6, Issue 2 · 15 Apr 2013 · 7,557 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Beneficial Effect of Asiaticoside on Experimental Neuropathy in Diabetic RatsChonlathip Thipkaew, Jintanaporn Wattanathorn, Supaporn MuchimapuraThough diabetic neuropathy produces high impact on quality of life, annual cost and morbidities, the therapeutic efficacy is still not in a satisfaction level. Based on the crucial role of oxidative stress on the pathophysiology of diabetic neuropathy and the improvement of this condition induced by antioxidant, we hypothesized that asiaticoside, a substance possessing antioxidant activity, could provide beneficial effect. … …American Journal of Applied Sciences, Vol. 9, Issue 11 · 31 Aug 2012 · 7,051 accessesView PDFCite