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106 results for “Therapeutic Effects”
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Research ArticleOpen accessIn the abstractComparative Phytochemical Analysis of Hydrodistilled Essential Oils of Scots Pine (Pinus Sylvestris L.) Needles From Central KazakhstanKuralay Tuleshova, Margarita Ishmuratova, Asanali Aynabayev et al.This study presents a detailed phytochemical investigation of hydrodistilled essential oils extracted from the needles of Pinus sylvestris (Scots pine), collected from fifteen natural populations located in the Karaganda and Ulytau regions of Central Kazakhstan. The extraction was performed using hydrodistillation with hexane as a co-solvent, and the chemical composition of the oils was subsequently analyzed using gas chromatography–mass spectrometry … …OnLine Journal of Biological Sciences, Vol. 25, Issue 4 · 28 Nov 2025 · 2,696 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffects of Atorvastatin on Oxidized Low-Density Lipoprotein-induced Proliferation, Apoptosis, and Matrix Metalloproteinase-9 Expression in Human MacrophagesBensheng Liu, Huifan Li, Yan Wang, Li ZhangAtorvastatin (ATV), an HMG-CoA reductase inhibitor, is utilized in the treatment of atherosclerotic diseases. Mononuclear Macrophages (MMs) are critical immune cells involved in atherosclerosis progression, participating in processes such as foam cell formation, cytokine secretion, and the development of fibrous cap and lipid core. To further elucidate the mechanism by which ATV exerts its therapeutic effects on atherosclerosis through the … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 3 · 18 Nov 2025 · 2,133 accessesView PDFCite
Research ArticleOpen accessIn the abstractAntiproliferative Potential of Pomegranate Peel Extract in MDA-MB Breast Cancer Cell LinesManal Asif Hamdulay, Fatema Yusuf Singaporewala, Grisilda Vidya Bernhardt et al.Nutraceuticals have gained recognition as adjuvant therapies in cancer treatment due to their non-toxic and protective properties. Among various natural products, pomegranate peel with high antioxidant capacity and rich polyphenol content suggest potential anticancer properties. Previous studies have shown promising anticancer effects of other parts of the pomegranate. The purpose of this research is to compare the effectiveness of Pomegranate … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 1 · 13 May 2025 · 5,582 accessesView PDFCite
Research ArticleOpen accessIn the abstractEvaluation of the Renoprotective Effects of Valsartan in Methotrexate-Induced Acute Kidney Injury in RatsDina KutbiMethotrexate (MTX) is a widely used chemotherapeutic agent known for its nephrotoxic effects, which can lead to acute kidney injury in hospitalized patients. However, the mechanism by which MTX induces nephrotoxicity is not entirely clear, but it is believed to involve oxidative stress and direct toxic effects on renal tubules. Valsartan, an angiotensin II receptor blocker, has been shown to … …OnLine Journal of Biological Sciences, Vol. 24, Issue 3 · 4 May 2024 · 4,571 accessesView PDFCite
Review ArticleOpen accessIn the abstractPotential Effects of Adropin in Subarachnoid HemorrhageZahra Hasanpour Segherlou, Mohammad Reza Hosseini Siyanaki, Brandon Lucke-WoldSubarachnoid Hemorrhage (SAH) typically, occurs in patients over 55 years of age and can cause a significant loss of productivity. SAH also has a high mortality rate and those who survive often suffer from early and secondary brain injuries that can result from the condition. By gaining a better understanding of the pathophysiology of SAH, it may be possible to … …Neuroscience International, Vol. 13, Issue 1 · 21 Jul 2023 · 9,237 accessesView PDFCite
Research ArticleOpen accessIn the abstractProduction of an Achillea millefolium (Yarrow) Toothpaste to Combat Gum and Tooth PainMunashe K. F. Chakamanga, Ashley Kumalo K, Dirk Hamadziripi MGum inflammation also known as gingivitis is primarily caused by the accumulation of dental plaque that forms on teeth. The inflammation triggers pain in the gums and surrounding tissues due to increased blood flow and immune activity aimed at combating the bacterial infection. Thus, this study was carried out to investigate the efficacy of Yarrow-based toothpaste in reducing gum inflammation. … …OnLine Journal of Biological Sciences, Vol. 26, Issue 4 · 9 Oct 2026 · 420 accessesView PDFCite
Research ArticleOpen accessIn the abstractLippia multiflora (Verbenacae, Mold.) Leaves Dietary Supplementation Effect on Broiler Chickens’ Growth, Hematological Parameters, and Serum BiochemistryKelemin Awa Koné, Tagouèlbè Tiho, Yapo Magloire Yapi, Vama Etienne TiaThe continued overuse of synthetic antibiotics has led to microbial resistance, responsible for numerous therapeutic failures in both animal and human health. This resistance has prompted the search for natural alternatives to the use of synthetic antibiotics in the poultry sector. The essay evaluated Lippia multiflora (Lm) leaves’ effects on chickens’ growth, health, and fatty acid profile. The rearing lasted … …OnLine Journal of Biological Sciences, Vol. 26, Issue 3 · 23 Sep 2026 · 429 accessesView PDFCite
Review ArticleOpen accessIn the abstractThe Intricate Relationship between Obesity and Type 2 DiabetesAnastasia V. Poznyak, Elizaveta M. Pleshko, Aleksandra S. Utkina et al.The rising prevalence of obesity and type 2 diabetes mellitus (T2DM) has emerged as one of the most pressing global public health challenges, profoundly impacting various demographic groups worldwide. This review synthesizes recent epidemiological data and explores the intricate biochemical mechanisms linking obesity to T2DM. We highlight the multifactorial nature of obesity, characterized by excessive adipose tissue, systemic inflammation, and … …OnLine Journal of Biological Sciences, Vol. 26, Issue 1 · 9 Aug 2026 · 455 accessesView PDFCite
Research ArticleOpen accessIn the abstractUnveiling the Potential of Dombeya buettneri K.Schum As a Drug Agent: Molecular Docking of Compounds With Enzymes Linked to Diabetes and Neurodegenerative DiseaseEsther Emem Nwanna, Samuel Chima Ugbaja et al.This study investigated the mechanisms of Dombeya buettneri (snowball leafy) extracts on diabetes, hypertension, and neurodegenerative diseases. It compared extracts obtained using steep water (a by-product of corn wet milling) and aqueous water. The extracts were analyzed for total phenol, total flavonoid content, antioxidant activities such as FRAP, ABTS, NO, DPPH, iron-induced lipid peroxidation assay, degradation of deoxyribose (Fenton’s reaction), … …OnLine Journal of Biological Sciences, Vol. 25, Issue 4 · 1 Feb 2026 · 2,025 accessesView PDFCite
Research ArticleOpen accessIn the abstractDihydroartemisinin Attenuates HBV-Induced Proliferation and Migration in LO2 cells via EMT Pathway ModulationYingde Nong, Caifang Ma, Wei Huang et al.Dihydroartemisinin (DHA), a derivative of artemisinin, possesses well-documented anti-inflammatory properties. This study investigated the inhibitory effects of DHA on hepatitis B virus (HBV)-induced cellular alterations in LO2 cells and elucidated underlying molecular mechanisms. Serum interleukin-6 (IL-6) levels were measured in HBV patients and analyzed for correlations with HBsAg, anti-HBs, and HBeAg. In vitro, LO2 cells were infected with clinical HBV … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 3 · 8 Jan 2026 · 2,071 accessesView PDFCite