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604 articles for “Target”
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EditorialOpen accessEvery word in the titleFocalize the Structure of Myd88 in TLR Signaling Pathway to Modulate Innate Immune Response: New Target for Old DiseasesShuai Xing, Ping ZhouAll diseases have their Achilles’ Heel to target and this is especially true for immunorelated diseases which must be treated by targeting the immune system somewhere and somehow correctly. In the most recent decade, immunologists recognized that the Toll-Like Receptor (TLR) signaling pathway in innate immune system plays a double-edged role in the pathogenesis of many notorious diseases. Although the … …American Journal of Immunology, Vol. 13, Issue 3 · 6 Sep 2017 · 7,865 accessesView PDFCite
EditorialOpen accessEvery word in the titleNeutrophil Extracellular Traps as Therapeutic Targets for Inflammatory DiseaseRory R. KoenenNeutrophilic granulocytes, or neutrophils are the most abundant circulating white blood cell and constitute a first line of defense against pathogens. They are characterized by a large polymorphic lobular nucleus and the presence of many secretory granules in their cytoplasm. Neutrophils are essential for a functional host defense, as is evidenced by the occurrence of severe infections in individuals with … …American Journal of Pharmacology and Toxicology, Vol. 9, Issue 4 · 25 Feb 2015 · 8,740 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleAutomatic Target Recognition in Cluttered Visible ImageryM. Jasmine Pemeena Priyadarsini, K. Murugesan, Srinivasa Rao Inbathini et al.Detection of a target from among similar/dissimilar targets in a cluttered image is vital in automatic target recognition. A MACH filter is used for the target detection in cluttered imagery. The cluttered images are correlated using the filter formulated from training images. The target is expected to be detected in the first highest peak. MACH was assumed as an optimum … …Journal of Computer Science, Vol. 9, Issue 5 · 21 May 2013 · 6,927 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleFeatures Study on Target Fragmentation in the Collisions Of 24Mg and 28Si with Emulsion Nuclei at 3.7A GeVA. Abd EL-DaiemProblem statement: The process of nuclear fragmentation in interactions of 3.7A GeV 24Mg and 28Si nuclei with the different target nuclei in a nuclear emulsion have been investigated. Approach: The probability of interactions without any projectile fragment with charge Z≥2 is zero for hydrogen target, but increases by increasing the mass of the target. Results: The disruption of a projectile … …Physics International, Vol. 1, Issue 1 · 31 Mar 2010 · 7,674 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleEnergy Efficient Hidden Markov Model Based Target Tracking Mechanism in Wireless Sensor NetworksB. Amutha, M. PonnavaikkoProblem statement: Target tracking is a challenging application in Wireless Sensor Networks (WSNs) because it is computation-intensive and requires real-time location processing. This study proposes a practical target tracking system based on the Hidden Markov Model in a distributed signal processing framework. In this framework, wireless sensor nodes perform target detection and tracking, whereas target localization requires the collaborative signal … …Journal of Computer Science, Vol. 5, Issue 12 · 31 Dec 2009 · 7,177 accessesView PDFCite
Research ArticleOpen accessEvery word in the titlePerformance Enhancement of Underwater Target Tracking by Fusing Data of Array of Global Positioning System SonobuoysAhmed El-Shafie, Abdallah Osman, Aboelmagd Noureldin, Aini HussainProblem statement: An accurate knowledge of geographic positions of sonobuoys is critical for the conduct of antisubmarine warfare operations and detected target localization. Deployed from an airborne platform or a surface vessel, arrays of sonobuoys could be used to efficiently track and localize submarines. Lastly, some sonobuoys were being equipped with GPS for improving system accuracy and potentially allowing networked … …Journal of Computer Science, Vol. 5, Issue 3 · 31 Mar 2009 · 7,475 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleAn Inducible System for the Identification of Target Genes for a Regulator in MycobacteriaShruti Jain, Garima Khare, Pushplata Tripathi, Anil K. TyagiWe described principle and application of an inducible system for identification of target genes of a given mycobacterial protein with a regulatory function. This vector system, a promoterprobe vector, carries (i) promoterless lacZ as the reporter gene and (ii) the mycobacterial gene encoding the regulatory protein under the transcriptional control of the promoter of highly inducible mycobacterial gene encoding acetamidase. … …American Journal of Biochemistry and Biotechnology, Vol. 4, Issue 3 · 30 Sep 2008 · 7,255 accessesView PDFCite
Research ArticleOpen accessEvery word in the titletNOX (ENOX2) Target for Chemosensitization-Low-Dose Responses in the Hormetic Concentration RangeD. James Morre, Sara Dick, Elena Bosneaga et al.An emerging concept of cancer chemotherapy is that of chemosensitization. Most often applied to the treatment of drug-resistance cancers, chemosensitization has utility when such cancers are rendered drug sensitive through treatment with the sensitizing agent. A particularly striking example of chemosensitization is that encountered with the synthetic isoflavene phenoxodiol where patients with taxane- and/or platinum-resistant ovarian carcinoma once again become … …American Journal of Pharmacology and Toxicology, Vol. 3, Issue 1 · 31 Mar 2008 · 7,573 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleNumerical Analysis of Forward Expansion Characteristics of Ablated Plasma by Pulsed Ion-Beam Interaction with Al TargetChainarong Buttapeng, Masaru Yazawa, Nobuhiro HaradaThe main objective of the current study was to investigate the behavior of ablation plasma which was produced by irradiating pulsed ion-beam with a solid target of Al thin foil. The technique used here was called a forward expansion---beams irradiation and the ablation plasma expansion are in an opposite direction. A one-dimensional hydrodynamic model was used to simulate the dynamic … …American Journal of Applied Sciences, Vol. 4, Issue 2 · 28 Feb 2007 · 7,113 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleBiformer Attention and ASF-YOLO for Cordyceps Sinensis Target RecognitionRu Yang, Peng Wu, Zhentao QinCordyceps sinensis, a highly valued traditional Chinese medicine, faces challenges in collection due to inefficiencies in manual searching, strenuous labor, and the impact of subjective expertise. The integration of deep learning into Cordyceps sinensis identification is an unexplored area. To alleviate the manual labor and enhance the precision and speed of identifying Cordyceps sinensis, a novel detection approach that combines … …American Journal of Biochemistry and Biotechnology, Vol. 20, Issue 4 · 14 Nov 2024 · 4,550 accessesView PDFCite