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62 articles for “T-cell receptor”
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Research ArticleOpen accessIn the keywordscDNA Cloning and Characterization of the House Dust Mite Allergen Sui p 2Joshua Evans M. Bajao, John Donnie A. RamosSuidasia pontifica (Sp) is a House Dust Mite (HDM) species found in tropical urban residential areas which causes sensitization of up to 75% of allergic patients. Cloning of allergens from Sp is a significant initial step in understanding the clinical significance of this HDM species. The study describes the cloning and in silico characterization of the group 2 allergen gene … …American Journal of Biochemistry and Biotechnology, Vol. 16, Issue 2 · 14 May 2020 · 7,891 accessesView PDFCite
Research ArticleOpen accessIn the abstractIntegrated Analysis of Transcriptomic and Metabolomic Responses in Rice Resisting False SmutYanmin Yu, Haiying Liu, Hongtao Wu et al.Rice false smut, caused by Ustilaginoidea virens, is an important fungal disease that reduces both grain yield and quality. To dissect the molecular basis of resistance, we combined transcriptome sequencing and metabolite profiling in resistant and susceptible rice cultivars. Transcriptome sequencing revealed more than 8,500 genes with altered expression patterns after infection, while metabolite profiling detected over 700 significantly changed … …American Journal of Biochemistry and Biotechnology, Vol. 22, Issue 3 · 27 Aug 2026 · 1,071 accessesView PDFCite
Research ArticleOpen accessIn the abstractAntiproliferative Potential of Pomegranate Peel Extract in MDA-MB Breast Cancer Cell LinesManal Asif Hamdulay, Fatema Yusuf Singaporewala, Grisilda Vidya Bernhardt et al.Nutraceuticals have gained recognition as adjuvant therapies in cancer treatment due to their non-toxic and protective properties. Among various natural products, pomegranate peel with high antioxidant capacity and rich polyphenol content suggest potential anticancer properties. Previous studies have shown promising anticancer effects of other parts of the pomegranate. The purpose of this research is to compare the effectiveness of Pomegranate … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 1 · 13 May 2025 · 5,593 accessesView PDFCite
Review ArticleOpen accessIn the abstractThe Impact of Di-2-Ethylhexyl Phthalate (DEHP) in Focus on the Reproductive System and Toxicity in Rat or Mammalian ModelVenkataramanaiah Poli, Srinivasulu Reddy MotireddyAbsalan, F., Saremy, S., Mansouri, E., Moghadam, M. T., Moghadam, A. R. E., & Razie, G. (2016). Effects of Mono-(2-Ethylhexyl) Phthalate and Di-(2-Ethylhexyl) Phthalate Administrations on Oocyte Meiotic Maturation, Apoptosis and Gene Quantification in Mouse Model. Cell Journal, 18(4), 503–513. https://doi.org/10.22074/cellj.2016.4717 Acevedo‐Rodriguez, A., Kauffman, A. S., Cherrington, B. D., Borges, C. S., Roepke, T. A., & Laconi, M. (2018). Emerging … …American Journal of Pharmacology and Toxicology, Vol. 19, Issue 1 · 6 Jun 2024 · 13,008 accessesView PDFCite
Research ArticleOpen accessIn the abstractMechanism Analysis of Artemisinin and Artesunate as Lung Cancer Therapy Agents Through in Silico MethodDidik Harmoko, Vivitri Dewi Prasasty, Adi YulandiSeveral in vitro studies have focused on the ability of artemisinin and its derivatives to suppress lung cancer cells, but there are still many biological processes and mechanisms, such as the interactions between the active compounds (ligands) and receptors that are not well understood and require further research. Drug targeting for lung cancer will be more precise and the inhibition … …OnLine Journal of Biological Sciences, Vol. 24, Issue 3 · 15 Feb 2024 · 6,149 accessesView PDFCite
Research ArticleOpen accessIn the abstractVirtual Screening of CPP Conjugated Peptide as QcrB BCC Protein Inhibitors of Mycobacterium tuberculosis BacteriaMuhammad Ihsan Muttaqin, Manaman Huang, Usman Sumo Friend TambunanTuberculosis is a global leading cause of death, just below COVID-19 and ranked above HIV. This disease is caused by a pathogen called Mycobacterium tuberculosis, which spreads easily through the air and is known to remain latent in most people's bodies, about a quarter of the world's population. The current problems with TB also include two main concerns: The official … …OnLine Journal of Biological Sciences, Vol. 24, Issue 3 · 14 Mar 2024 · 5,523 accessesView PDFCite
Research ArticleOpen accessIn the abstractFSH Receptor and Ki-67 Protein Expressions of Endometrial Macaque in Mid-Luteal Phase after Exposure to Various Doses of Recombinant FSH and Fixed-Dose of GnRH AgonistNurhuda Sahar, Ponco Birowo, Rosalina Thuffi et al.There are many advances in Assisted Reproductive Technologies (ARTs). However, implantation rates are still low. The embryo implantation is a mutual interaction between the blastocyst and endometrium. This study aimed to investigate the endometrial cell proliferation stimulated by recombinant Follicle-Stimulating Hormone (rFSH) in various doses by looking at FSH-Receptor (FSHR) and Ki-67 protein expressions. The studied samples were Stored Biological … …OnLine Journal of Biological Sciences, Vol. 21, Issue 2 · 28 May 2021 · 6,349 accessesView PDFCite
Literature ReviewOpen accessIn the abstractFundamental Questions about γδT CellsMoulay Yassine Belghali, Saadia Ba-M’hamed, Mouna Khouchani, Brahim AdmouγδT cells is a minor subgroup of T lymphocytes expressing γδ-T Cell Receptor (TCR), with many subsets, dominated by Vδ2 and Vδ1. γδT cells recognize antigens independently of the context of MHC class I, MHC class II, or CD1 presenting molecules. However, this recognition requires the expression of the transmembrane Butyrophilin proteins by the presenting cells. Their activation is controlled … …OnLine Journal of Biological Sciences, Vol. 20, Issue 4 · 15 Dec 2020 · 6,384 accessesView PDFCite
Research ArticleOpen accessIn the abstractSynthesis, Ant Proliferative Activity and Docking Study of New Quercetin Derivatives against MDA-MB231 Breast Cancer Cell LinesReham Adnan Al-Anssari, Rita S. Elias, Shaker A.N. AljadaanMDA-MB231 is a very aggressive and invasive triple negative breast cancer, which present with limited treatment options. Unlike other breast cancer types, it is characterized by absence of hormonal receptors of estrogen, progesterone as well as human epidermal growth factor receptor 2, rendering it unsuitable for hormonal therapy and a perfect candidate for chemotherapy. Quercetin is a common natural flavonoid … …American Journal of Applied Sciences, Vol. 16, Issue 5 · 26 Jun 2019 · 8,796 accessesView PDFCite
EditorialOpen accessIn the abstractFocalize the Structure of Myd88 in TLR Signaling Pathway to Modulate Innate Immune Response: New Target for Old DiseasesShuai Xing, Ping ZhouAll diseases have their Achilles’ Heel to target and this is especially true for immunorelated diseases which must be treated by targeting the immune system somewhere and somehow correctly. In the most recent decade, immunologists recognized that the Toll-Like Receptor (TLR) signaling pathway in innate immune system plays a double-edged role in the pathogenesis of many notorious diseases. Although the … …American Journal of Immunology, Vol. 13, Issue 3 · 6 Sep 2017 · 7,865 accessesView PDFCite