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116 articles for “SIR”

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Research ArticleOpen accessEvery word in the titleThe Silencing of Septin 1 via Synthetic siRNAs in Schizosaccharomyces pombeSemih Ekimler, Merve Yilmazer, Ercan AricanSeptins are evolutionary conserved GTP-binding proteins and form heterooligomers in cells to interact with cytoskeleton. The main roles of septins in cell are cytokines, membrane interactions, vesicle trafficking and microtubule and actin organization. Non-coding RNAs are key players of gene expression regulation. Small-interfering RNAs (siRNAs) belong to non-coding RNAs, are characterized by sequence complementarity to their target mRNAs. siRNAs silence … …OnLine Journal of Biological Sciences, Vol. 17, Issue 1 · 31 Mar 2017 · 7,237 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleBiosurfactan Production by Bacillus sp. Isolated from Petroleum Contaminated Soils of Sirri IslandM. Ghayyomi Jazeh, F. Forghani, Deog-Hwan OhProblem statement: Biosurfactants are active surface components produced by some bacteria and fungi. These molecules reduce surface and interfacial tension in aqueous solutions and hydrocarbon mixtures. The most important application of biosurfactants is in oil industry to enhance oil quality and facilitate oil extraction. The aim of this study was to isolate biosurfactant producing bacteria and optimize the conditions like … …American Journal of Applied Sciences, Vol. 9, Issue 1 · 13 Jan 2012 · 8,552 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleRETRACTED: Sonoporation Enhances Liposome Mediated EcTRAF4 siRNA Delivery in SaB-1 CellsMeng Han Chen, Wang Chung PingThe article has been retracted after careful consideration and internal assessment, we have identified significant errors in the experimental design and data presentation, which compromise the integrity and validity of the findings reported in the article. …American Journal of Biochemistry and Biotechnology, Vol. 19, Issue 2 · 17 May 2023 · 5,221 accessesView PDFCite
Research ArticleOpen accessIn the keywordsIdentification of Influential Nodes With Topological Structure Via GRAPH Neural Network (GNN) Approach in Social Media NetworksRajnish Kumar, Laxmi Ahuja, Suman Mann, Sanmukh KaurThe amount of data in social networks is vast these days, and constantly changing, making influential node identification crucial. The existing topologies are constantly changing due to the evolving behavior of the applied dataset. Node and leaf topology or feature-based value form the basis for machine learning and centrality computation. Hence, influential node value determination is based on the node … …Journal of Computer Science, Vol. 22, Issue 2 · 17 Feb 2026 · 1,830 accessesView PDFCite
Research ArticleOpen accessIn the keywordsPrediction of Covid-19 Outbreak in India by Employing Epidemiological ModelsSudheer Reddy K, Anji Reddy V, Mamatha K, Santhosh Kumar CThe novel Corona virus (Covid-19) pandemic has frightened an unprecedented challenge to continents. The Covid-19 pandemic is a highly contagious viral disease that has been progressing across the globe. The global thought leaders, doctors, scientists and other intellects have enforced the lockdown to reduce the spread of the pandemic. The objective is to study the impact of lockdown and to … …Journal of Computer Science, Vol. 16, Issue 7 · 10 Jul 2020 · 6,903 accessesView PDFCite
Research ArticleOpen accessIn the keywordsPreparation of Low-Sugar Herbal Buccal Tablet and its Antioxidant ActivityYuqing Wang, Mingjie Sun, Rui Xu et al.In this study, in order to prepare a low-sugar Herbal Buccal Tablet (HBT), Response Surface Methodology (RSM) was used to optimize the formula of HBT. HBT was prepared by wet granulation and tableting process on the basis of formula optimization. The in vitro antioxidant activity, glycemic index and particle microstructure of HBT were evaluated. The results showed that the optimal … …American Journal of Biochemistry and Biotechnology, Vol. 18, Issue 1 · 8 Mar 2022 · 6,357 accessesView PDFCite
Research ArticleOpen accessIn the keywordsIncidence of Cystic Echinococcosis in Libya: I. Seroprevalence of Hydatid Disease in Sheep and Goats Naturally Exposed to the Infection in the North Midland RegionMohamed M. Ibrahem, Badereddin B. Annajar, Wafa M. IbrahemHydatid disease is one of the most and serious public health and veterinary problems in Libya and other North African countries. Thirteen rural villages of two main districts bordered to each other at the north midland of the country namely, Misrata which is almost agricultural area and about 200 km east of Tripoli and Sirt which is almost pasture area … …American Journal of Animal and Veterinary Sciences, Vol. 11, Issue 3 · 28 Oct 2016 · 7,418 accessesView PDFCite
Review ArticleOpen accessIn the keywordsImmunology of Septic Shock and Traumatic Injury: A ReviewWilliam Heuser, Marianne Frieri, Krishan Kumar, Anthony BoutinSepsis remains a major worldwide cause of morbidity and mortality and remains amongst the leading causes of death in medical Intensive Care Units (ICUs). Increasing injury severity associated with trauma is a significant independent risk factor for sepsis and many of these patients require intensive care unit resource utilization with increased rates of mortality. There are many postulated theories regarding … …American Journal of Immunology, Vol. 11, Issue 4 · 31 Dec 2015 · 7,003 accessesView PDFCite
Research ArticleOpen accessIn the keywordsA SHORT INTERFERING RNA MOLECULAR BEACON FOR THE ATTENUATION OF MYCOBACTERIAL INFECTIONRemo George, Kathy Nugent, Norman Bolus et al.The ability of the pathogen Mycobacterium Tuberculosis (MTB) to invade and survive within macrophages of granulomas is attributed to the product of the Mammalian Cell Entry (MCE) operon whose gene, mce4A, encodes a cholesterol transporter that transports host lipids into the bacterium that allows the bacterium to survive during chronic infection. Here, we proposed and tested the hypothesis that a … …American Journal of Biochemistry and Biotechnology, Vol. 10, Issue 1 · 4 Mar 2014 · 7,774 accessesView PDFCite
Research ArticleOpen accessIn the keywordsMicroarray Analysis of Human Vascular Smooth Muscle Cell Responses to Bacterial LipopolysaccharideJoe Minta James, J. Yun, Sandy Der, Shikha RanaAccumulating evidence suggest a causal role of bacterial and viral infections in atherogenesis. Bacterial lipopolysaccharide (LPS) has been shown to stimulate resting vascular smooth muscle cells (SMC) with the production of inflammatory cytokines and modulation of quiescent cells to the proliferative and synthetic phenotype. To comprehensively identify biologically important genes associated with LPS-induced SMC phenotype modulation, we compared the transcriptomes … …American Journal of Immunology, Vol. 3, Issue 2 · 31 Dec 2007 · 6,994 accessesView PDFCite