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Tips: “quotes” for a phrase · author:Lee · a DOI goes straight to its article

12 results for “Refractory”
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Research ArticleOpen accessIn the abstractImmune-Based Therapies for Spinal Cord InjuryBasem I. Awad, Davina V. Gutierrez, Michael P. SteinmetzTraumatic Spinal Cord Injury (SCI) results in both focal and diffuse spinal cord pathologies that are exacerbated by an inflammatory response after the initial injury. Resident and infiltrating immune cells contribute significantly to the growth-refractory environment near the lesion and can intensify damage to spared tissue, resulting in impaired spontaneous functional recovery. Numerous studies have demonstrated that several immunomodulatory therapies … …Neuroscience International, Vol. 4, Issue 1 · 17 Apr 2013 · 6,884 accessesView PDFCite
Research ArticleOpen accessIn the abstractClozapine and its Major Stable Metabolites, N-desmethylclozapine and Clozapine N-oxide do not Affect Human Bone Marrow Stromal Cells in vitroAvril Pereira, Brian DeanTreatment of refractory schizophrenia with the atypical antipsychotic drug clozapine is associated with life-threatening agranulocytosis, characterised by a drop in neutrophil count. Theoretically, toxicity may be accounted for by direct action of parent drug or one of its stable metabolites on bone marrow stroma given importance of these cells to neutrophil maturation. Effects of clozapine, N-desmethylclozapine and clozapine N-oxide on … …American Journal of Pharmacology and Toxicology, Vol. 1, Issue 1 · 31 Mar 2006 · 7,111 accessesView PDFCite