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24 articles for “Placebo group”
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Research ArticleOpen accessIn the abstractDietary Beta-1,3/1,6-Glucans Reduce Clinical Signs of Canine AtopyA. C. Beynen, D. H.J. Saris, P. M. Paap et al.Problem statement: There was evidence that beta-1,3/1,6-glucans modulate inflammatory activity. In an open, non-controlled trial, purified beta-1,3/1,6-glucans were found to improve the clinical signs of dogs with undefined chronic skin disorders. Given the design of that study, further work was required on the efficacy of beta-1,3/1,6-glucans in the treatment of canine atopy. Approach: The influence of a purified preparation of … …American Journal of Animal and Veterinary Sciences, Vol. 6, Issue 4 · 9 Jan 2012 · 9,979 accessesView PDFCite
Research ArticleOpen accessIn the abstractToxicological Evaluation of Aspilia Africana Leaf Extracts in MiceO. O.K. Oko, E. A. Agiang, E. E. Osim, O. R. AsuquoProblem statement: The degree of toxicity of crude extracts of Aspilia Africana (Bush marigold) leaf on the basis of routes and dosages of administration were investigated. 204 healthy, male Swiss albino mice (20-25g) were used in three consecutive studies. Approach: In the first and second study, oral and intraperitoneal doses of 100, 500, 1000, 2000 and 4000 mg kg-1 body … …American Journal of Pharmacology and Toxicology, Vol. 6, Issue 3 · 28 Nov 2011 · 8,184 accessesView PDFCite
Research ArticleOpen accessIn the abstractGinger Supplementation Enhances Working Memory of the Post-Menopause WomenNaritsara Saenghong, Jintanaporn Wattanathorn, Terdthai Tong-Un et al.Problem statement: Cognitive impairment is one important problem in post-menopausal women. Although hormone therapy can improve this condition, it also produces adverse effect. Recent findings showed that this condition could be mitigated by the herb. Ginger or Zingiber officinale Roscoe, a plant in a family of Zingiberaceae, was previously demonstrated the neuroprotection and cognitive enhancing effects. Therefore, this study was … …American Journal of Applied Sciences, Vol. 8, Issue 12 · 10 Oct 2011 · 10,065 accessesView PDFCite
Research ArticleOpen accessIn the abstractImpact of Dietary Polydextrose on Clinical Signs of Canine OsteoarthritisA. C. Beynen, D. H.J. Saris, L. De Jong et al.Problem statement: Osteoarthritis is an inflammatory joint disease associated with loss of cartilage matrix. There is suggestive evidence that the intake of polydextrose fiber has anti-inflammatory activity. It was reasoned that polydextrose may have a positive influence on canine osteoarthritis. Approach: A double-blind, placebo-controlled trial with privately owned dogs was carried out to assess the efficacy of STA-LITE® polydextrose in … …American Journal of Animal and Veterinary Sciences, Vol. 6, Issue 3 · 5 Oct 2011 · 9,052 accessesView PDFCite
Research ArticleOpen accessIn the abstractClinical Signs of Hairballs in Cats Fed a Diet Enriched with CelluloseA. C. Beynen, J. Middelkoop, D. H.J. SarisProblem statement: The intake of cellulose may delay gastric emptying and raise the intestinal transit rate. These effects could antagonize hairball formation. Thus, it was hypothesized that a diet enriched with a cellulose preparation (Arbocel BWW40®), forming a completely insoluble fiber network, would diminish the severity of clinical symptoms of hairballs in cats. Approach: In a double-blind, placebo-controlled trial with … …American Journal of Animal and Veterinary Sciences, Vol. 6, Issue 2 · 8 Aug 2011 · 11,909 accessesView PDFCite
Research ArticleOpen accessIn the abstractSafety and Efficacy of an Ayurvedic Formulation Cystone in Management of Ureteric Calculi: A Prospective Randomized Placebo Controlled StudyN.K. Mohanty, R.L. Nayak, Pralhad S. PatkiProblem statement: Medical management of urolithiasis is still a challenge for modern medical practice. In the present study, Cystone tablet, an Ayurvedic formulation claimed to be useful in urolithiasis was evaluated for its safety and efficacy in reduction or expulsion of ureteric calculi and to assess the role of Cystone in relieving the clinical symptoms. Approach: This was a prospective … …American Journal of Pharmacology and Toxicology, Vol. 5, Issue 2 · 30 Jun 2010 · 12,360 accessesView PDFCite
Research ArticleOpen accessIn the abstractOral Administration of Gelatin Hydrolysate Reduces Clinical Signs of Canine Osteoarthritis in a Double-Blind, Placebo-Controlled TrialA.C. Beynen, H.W. Van Geene, H.V. Grim et al.Problem statement: There are indications that the intake of gelatin hydrolysate has a beneficial impact on the clinical signs of osteoarthritis in dogs. Data from a controlled trial were required to substantiate these indications. Approach: A double-blind, placebo-controlled trial with privately owned dogs was carried out to assess the efficacy of a preparation of gelatin hydrolysate in the treatment of … …American Journal of Animal and Veterinary Sciences, Vol. 5, Issue 2 · 30 Jun 2010 · 18,245 accessesView PDFCite
Research ArticleOpen accessIn the abstractInfluence of Dietary Beta-1,3/1,6-Glucans on Clinical Signs of Canine Osteoarthritis in a Double-Blind, Placebo-Controlled TrialA.C. Beynen, E. LegersteeProblem statement: There are indications for a beneficial effect of beta-1,3/1,6-glucans on the clinical signs of dogs with osteoarthritis. Data from a controlled trial were necessary to prove or disprove the indications. Approach: A double-blind, placebo-controlled trial with privately owned dogs was carried out to assess the efficacy of a preparation of beta-1,3/1,6-glucans in the treatment of osteoarthritis. With the … …American Journal of Animal and Veterinary Sciences, Vol. 5, Issue 2 · 30 Jun 2010 · 10,105 accessesView PDFCite
Research ArticleOpen accessIn the abstractQuality of Life in Hematologic Cancer Patients: A Randomized Clinical Trial of Low Dose Naltrexone Versus PlaceboMohammad Ali Seifrabiei, Mohammad Abbasi, Ali Montazeri et al.This study aimed to investigate its effect on hematologic cancer patients. This was a randomized controlled trial assessing quality of life in patients with hematologic malignancies from a single institute in Hamedan. Patients were allocated into two study arms and in addition to their routine treatment received either daily naltrexone 3 mg capsules (treatment group) or 3 mg starch (placebo … …American Journal of Applied Sciences, Vol. 5, Issue 7 · 31 Jul 2008 · 7,399 accessesView PDFCite
Research ArticleOpen accessIn the abstractEvaluation of Local Injection of 0.5% Bupivacaine + 1/200000 Epinephrine for Post Tonsillectomy Pain ReductionKeramat Mozafarinia, Maryam AmizadehTo determine the effectiveness of postoperative local infiltration of Bupivacaine in decreasing post tonsillectomy pain. A double blind randomized clinical trail was conducted. Treatment group was administered 3-10 ml 0.5% Bupivacaine + 1/200000 Epinephrine solution and control group was received 3-10 ml normal saline, locally. Outcome was post surgical pain, which measured by visual analogue scale (VAS), after 6, 12, … …American Journal of Pharmacology and Toxicology, Vol. 2, Issue 2 · 30 Jun 2007 · 7,659 accessesView PDFCite