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30 results for “Placebo”
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Research ArticleOpen accessIn the abstractβ-carotene Supplementation Does Not Improve Milk Yield and Milk Components of Saanen GoatsDominic Lado Marino Gore, Khoboso Christina LehloenyaWe hypothesized that supplementing goats with β-carotene would increase milk yield and improve milk quality. Therefore, the current study aimed at evaluating the effect of supplemental β-carotene on milk yield and milk components. Goats were divided into two groups, one group received β-carotene 100 and 50 mg/head/day before and during the drying off period, respectively, while the second group received … …American Journal of Animal and Veterinary Sciences, Vol. 15, Issue 2 · 19 May 2020 · 6,761 accessesView PDFCite
Research ArticleOpen accessIn the abstractSafety Assessment of Indigenous Probiotic Strain Lactobacillus plantarum Dad-13 Isolated from Dadih Using Sprague Dawley Rats as a ModelEndang S Rahayu, Ilzamha H Rusdan, Armita Athennia et al.Lactobacillus plantarum Dad-13 is a probiotic candidate from dadih, a traditional fermented buffalo milk from West Sumatera, Indonesia. This study aimed to evaluate safety aspects of L. plantarum Dad-13 in high dose consumption on Sprague Dawley rats. Two treatment groups were fed with 1011 CFU/mL/day of L. plantarum Dad-13 for 14 and 28 days respectively. Two placebo groups were fed … …American Journal of Pharmacology and Toxicology, Vol. 14, Issue 1 · 12 Nov 2019 · 10,134 accessesView PDFCite
Research ArticleOpen accessIn the abstractSildenafil in the Treatment of Postoperative Hypoxemia with High Resistance in Cyanotic Congenital Heart DiseaseZhou Jiawang, Lv Yong, Hu Zhendong et al.This study was designed to determine the effect of sildenafil treatment on postoperative hypoxemia with high resistance in cyanotic congenital heart disease. A total of 247 cases of cyanotic congenital heart disease were operated on from May 2006 to August 2014. Only 45 cases exhibited postoperative hypoxemia after symptomatic treatment. Sildenafil at doses of 0.30-5 mg/kg every 6 h was … …American Journal of Biochemistry and Biotechnology, Vol. 13, Issue 3 · 1 Sep 2017 · 7,682 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffect of Stevia Consumption on Blood Pressure, Stress Hormone Levels and Anthropometrical Parameters in Healthy PersonsEmad A.S. Al-Dujaili, Husni Twaij, Yazan A. Bataineh et al.Stevia is a natural sweetener containing steviol glycosides known to be several times sweeter than sucrose. It is thought to have several beneficial properties though some evidence state it may have detrimental effects. The aim of this study was to investigate the potential beneficial or harmful effects of stevia consumption by exploring its effects on blood pressure, stress hormone levels … …American Journal of Pharmacology and Toxicology, Vol. 12, Issue 1 · 31 Aug 2017 · 25,775 accessesView PDFCite
Review ArticleOpen accessIn the abstract"Ebola Ça Suffit!" is not enough to Prove Efficacy of an Ebola VaccineDavid R CroweA recently published Ebola vaccine trial claimed an almost perfect result with no cases of Ebola after the vaccine had time to take effect - a vaccine efficacy of 100%. This article is a detailed review of the information published about the trial and, particularly, this claim. The trial design was sub-optimal because randomization was only partial (and one treatment … …American Journal of Immunology, Vol. 13, Issue 3 · 8 Jul 2017 · 17,825 accessesView PDFCite
Review ArticleOpen accessIn the abstractAbout Homeopathy or ≪Similia Similibus Curentur≫Raffaella Aversa, Relly Victoria V. Petrescu, Antonio Apicella, Florian Ion T. PetrescuHomeopathy or homoeopathy (from the Greek όμοιος/homoios, "similar" and πάθος/pathos, "suffering" or "disease") is a science created by Samuel Hahnemann in 1796. The homeopathic practice rests on three principles: The similarity, the individualization of cases and the infinitesimal. The use of the infinitesimal was proposed by Hahnemann in the early nineteenth century with the publication of "Organon der Heilkunst" (Organon … …American Journal of Engineering and Applied Sciences, Vol. 9, Issue 4 · 16 Dec 2016 · 11,553 accessesView PDFCite
EditorialOpen accessIn the abstractAre we Able to Harness the Immunomodulatory Power of Cytokines for Novel Autoimmune Disease Treatments?Giuseppe Nocentini, Graziella Migliorati, Carlo RiccardiSince the end of the 1970s, interleukin 2 (IL-2) has been known as a key player in T cell expansion/activation (Watson et al., 1980). In the late 1980s, some groups used IL-2 to stimulate the immune systems of tumour patients (Jacobs et al., 1986). The idea seemed brilliant and several attempts were made, but the results were disappointing (Lim et … …American Journal of Pharmacology and Toxicology, Vol. 10, Issue 2 · 22 Oct 2015 · 7,625 accessesView PDFCite
EditorialOpen accessIn the abstractImpact of Quantitative Pharmacology on Drug DevelopmentAna Ruiz-Garcia, Kourosh ParivarThesuccess of drug development rests over two well defined pillars, a goodunderstanding of the drug’s clinical pharmacology and the appropriate targetpopulation for whom the clinical use is intended. The label for human prescription drugsrequires a good understanding of the pharmacological effects (pharmacodynamicsor PD) and the mechanism of action of the drug as well as detailed informationof the drug’s Pharmacokinetics (PK): … …American Journal of Pharmacology and Toxicology, Vol. 9, Issue 4 · 24 Apr 2015 · 7,158 accessesView PDFCite
Research ArticleOpen accessIn the abstractAlzheimer’s Disease Prognosis is Captured by a Down-Upsized Incidence Poisson DistributionRamalingam ShanmugamAlzeimer disease is a daunting nightmare to both the medical and families of the patients. Tireless efforts are made by the medical researchers to treat Alzheimer’s patients. The Alzhiemer patients’ data provides clues about its prognosis and they can be identifies when the data are analyzed and understood correctly. The data analysis is a first step in the path to … …Current Research in Medicine, Vol. 4, Issue 2 · 4 Sep 2013 · 6,926 accessesView PDFCite
Research ArticleOpen accessIn the abstractIs Cancer Recurrence Postponed By a Treatment? A New Model AnswersRamalingam ShanmugamDuring a treatment period of a cancer patient, the medical team ponders over a question: Is patient’s cancer recurrence significantly postponed by the medication, even if the illness is not completely cured? This question could be answered with data evidence if the data are analyzed with an appropriate model and a suitable methodology. A scanning of the literature reveals that … …Current Research in Medicine, Vol. 4, Issue 1 · 26 Mar 2013 · 6,887 accessesView PDFCite