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167 results for “Oxidative stress”
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Research ArticleOpen accessPhrase in the titleEFFECTS STUDY OF NIGELLA SATIVA, ITS OIL AND THEIR COMBINATION WITH VITAMIN E ON OXIDATIVE STRESS IN RATSAmr A. RezqAntioxidants or free radical scavengers are very important in protecting the living cells against any damage induced by free radicals. The effects of Nigella Sativa Extract (NSE), Nigella Sativa Oil (NSO) and Vitamin E (Vit. E) and the combination of NSE or NSO with Vit. E on potassium bromate (KBrO3)-induced oxidative stress in male rats were investigated. Forty nine Sprague … …American Journal of Applied Sciences, Vol. 11, Issue 7 · 23 Apr 2014 · 7,005 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleAntiretroviral Toxicity and Oxidative StressAdikwu Elias, Brambaifa Nelson, Deo Oputiri, Oru-Bo Precious GeoffreyAntiretroviral drugs are used for the treatment of human immunodeficiency virus, they are used as combination regimens to achieve the highest possible benefit, tolerability, compliance and to diminish the risk of resistance development. Reports from preclinical and clinical studies have linked antiretrovirals with some toxicological effects which could be associated with redox imbalance (oxidative stress). This stimulated us to review … …American Journal of Pharmacology and Toxicology, Vol. 8, Issue 4 · 20 Nov 2013 · 8,255 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleEvaluation of Thai Style Stretching Exercise on "Ruesi Dud Ton" on Physical Health and Oxidative Stress in Healthy VolunteerJintanaporn Wattanathorn, Tasanee Boonterm, Wipawee Thukhummee et al.Despite the health benefit reputation of Thai stretching exercise "Ruesi dud ton", no scientific evidence is available. Therefore, we aimed to determine the effect of Thai style stretching exercise on physical health and oxidative stress markers including Malondialdegyde (MDA) level and the activities of main scavenger enzymes including Superoxide Dismutase (SOD), Catalase (CAT) and Glutathione Peroxidase (GSH-Px). We had determined … …OnLine Journal of Biological Sciences, Vol. 12, Issue 4 · 22 Feb 2013 · 7,739 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleHepatoprotective Effect of Taurine Against Oxidative Stress Due to Methotrexate in RatE. Issabeagloo, M. Taghizadiyeh, P. KermanizadehProblem statement: Taurine, 2-aminoethanesulphonic acid is an essential amino acid. It is present at high concentrations in many tissues. It plays important roles in numerous physiological functions including conjugation with bile acids, modulation of calcium levels and maintenance of osmolarity, antioxidation and stabilization of membranes. Methotrexate (MTX), as the most disease modifying anti-rheumatic drug used for Rheumatoid Arthritis (RA), has … …American Journal of Animal and Veterinary Sciences, Vol. 6, Issue 4 · 16 Jan 2012 · 8,495 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleEffect of Garcinia Atroviridis on Oxidative Stress and Atherosclerotic Changes in Experimental Guinea PigsAdel. A. Amran, Zaiton Zakaria, Faizah Othman, Paden MoratProblem statement: Oxidative stress plays a major role in hypercholesterolemia induced atherosclerosis. Garcinia atroviridis has been shown to exhibit antioxidant properties. Approach: The present study aimed to investigate the effect of Garcinia atroviridis on the oxidative stress in guinea pigs fed with high cholesterol diet. Twenty-four male Guinea pigs were divided into four groups. Group I served as control while … …American Journal of Pharmacology and Toxicology, Vol. 5, Issue 2 · 30 Jun 2010 · 9,035 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleCamel's Milk Alleviates Oxidative Stress and Lipid Peroxidation Induced by Chronic Aluminum Chloride Exposure in Rat's TestesFahaid H. Al-HashemProblem statement: The present study was carried out to examine the effectiveness of Camel’s milk in alleviating aluminum chloride (AlCl3)-induced oxidative stress and lipid peroxidation in rat testes. Approach: White albino male rats (230-250 g) were divided into three groups of 10 rats: A control group, treated with normal saline and two experimental groups, the AlCl3 treated group and the … …American Journal of Applied Sciences, Vol. 6, Issue 11 · 30 Nov 2009 · 7,429 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleCamel's Milk Protects Against Aluminum Chloride-Induced Normocytic Normocromic Anemia, Lipid Peroxidation and Oxidative Stress in Erythrocytes of White Albino RatsFahaid Al-HashemProblem statement: Aluminum (Al) is an indifferent element from a toxicological point of view. In recent years, however, Al has been implicated in the pathogenesis of several clinical disorders. One of the most frequently described problem in aluminum toxicity is anemia. The present study was carried out to determine the effectiveness of Camel’s milk in alleviating the toxicity of aluminum … …American Journal of Biochemistry and Biotechnology, Vol. 5, Issue 3 · 30 Sep 2009 · 8,021 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleA Novel Rodent Model of Autism: Intraventricular Infusions of Propionic Acid Increase Locomotor Activity and Induce Neuroinflammation and Oxidative Stress in Discrete Regions of Adult Rat BrainDerrick F. MacFabe, Karina Rodríguez-Capote, Jennifer E. Hoffman et al.Innate neuroinflammatory changes, increased oxidative stress and disorders of glutathione metabolism may be involved in the pathophysiology of autism spectrum disorders (ASD). Propionic acid (PPA) is a dietary and gut bacterial short chain fatty acid which can produce brain and behavioral changes reminiscent of ASD following intraventricular infusion in rats. Adult Long-Evans rats were given intraventricular infusions of either PPA … …American Journal of Biochemistry and Biotechnology, Vol. 4, Issue 2 · 30 Jun 2008 · 12,613 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleOxidative Stress in Autism: Elevated Cerebellar 3-nitrotyrosine LevelsElizabeth M. Sajdel-Sulkowska, Boguslaw Lipinski, Herb Windom et al.It has been suggested that oxidative stress and/or mercury compounds play an important role in the pathophysiology of autism. This study compared for the first time the cerebellar levels of the oxidative stress marker 3-nitrotyrosine (3-NT), mercury (Hg) and the antioxidant selenium (Se) levels between control and autistic subjects. Tissue homogenates were prepared in the presence of protease inhibitors from … …American Journal of Biochemistry and Biotechnology, Vol. 4, Issue 2 · 30 Jun 2008 · 17,119 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleHormesis and Exercise: How the Cell Copes with Oxidative StressLi Li Ji, Zsolt Radak, Sataro GotoContraction-induced production of reactive oxygen and nitrogen species has been shown to cause oxidative stress to skeletal muscle, heart and other organs. As an adaptive response, muscle antioxidant defense systems are upregulated in response to exercise to restore intracellular prooxidantantioxidant homeostasis. Thus, both young and old animals and humans involved in regular exercise have shown reduced oxidative damage during acute … …American Journal of Pharmacology and Toxicology, Vol. 3, Issue 1 · 31 Mar 2008 · 7,817 accessesView PDFCite