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28 results for “Nitric Oxide”

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Research ArticleOpen accessIn the keywordsIn vitro Activation of Human and Rat Lymphocyte and Macrophage Functions by NorepinephrineRicardo Gomez-Flores, Diana Caballero-Hernandez, Richard J. Weber et al.Norepinephrine (NE) has been associated not only with increasing blood pressure, atherosclerosis, heart disease, and other life threatening conditions, but also with altering immune responses by influencing leukocyte functions. In the present study, we evaluated the in vitro effects of NE on rat thymic lymphocyte and human peripheral blood mononuclear cells (HPBMC) functions. We observed that NE marginally, but significantly … …American Journal of Immunology, Vol. 1, Issue 4 · 31 Dec 2005 · 7,075 accessesView PDFCite
Research ArticleOpen accessIn the keywordsSelective Lymphocyte Activation and Inhibition of In Vitro Tumor Cell Growth by Novel MorphinansRicardo Gomez-Flores, Kimberly R. Vietti, William J. Dunn et al.Opioids can suppress immune functions and increase susceptibility to developing cancer and infectious diseases. Recently, novel opioid compounds have been synthesized that lack immunosuppressive effects. We evaluated the effects of morphinans with substituted pyrimidine (methyl, phenyl, hydroxy, and amino groups) and pyrazole groups on in vitro rat thymic lymphocyte and splenic macrophage functions, and tumor cell growth. We observed that … …American Journal of Immunology, Vol. 2, Issue 1 · 5 Mar 2005 · 7,078 accessesView PDFCite
Research ArticleOpen accessIn the keywordsSitagliptin Impairs Healing of Experimentally Induced Gastric Ulcers Via inhibition of iNOS and COX-2 ExpressionAmina Unis, Eman AbdelzaherGastric ulcer healing is a complex process that is regulated by several promoting factors including COX-2 and iNOS. Diabetes mellitus is usually associated with delayed gastric ulcer healing. Hence, the current study was designed to investigate the effect of sitagliptin (dipeptidyl peptidase-4 inhibitor) on gastric ulcer healing and expression of iNOS and COX-2 in rat stomach.The study was conducted on … …American Journal of Pharmacology and Toxicology, Vol. 8, Issue 3 · 4 Sep 2013 · 7,436 accessesView PDFCite
Research ArticleOpen accessIn the keywordsEfficacy Assessment of Kaempferia parviflora for the Management of Erectile DysfunctionPanakaporn Wannanon, Jintanaporn Wattanathorn, Terdthai Tong-Un et al.Age-related decline in erectile function is a noted phenomenon worldwide. A variety of medicinal plants have been identified as having strong aphrodisiac properties along with the ability to improve erectile functioning. Kaempferia Parviflora (KP) has famous as a Thai Viagra and use it to increase male impotency. However, there is limited scientific evidence regarding the efficacy of this herb on … …OnLine Journal of Biological Sciences, Vol. 12, Issue 4 · 4 Feb 2013 · 19,852 accessesView PDFCite
Research ArticleOpen accessIn the keywordsEffect of Intraperitoneally Injection of Different Doses of Lovastatin on Pain and Inflammatory Response Induced by Formalin in MiceKhayatnouri MirhadiProblem statement: The 3-Hydroxy-3-Methyl Glutaryl-CoA (HMG-CoA) reductase inhibitors (statins) have been unequivocally shown to reduce cardiovascular morbidity and mortality. Their lipid-lowering actions are by reversible and competitive inhibition of the enzyme HMG-CoA reductase, a precursor of cholesterol. It has been suggested that statins appear to have therapeutic benefits in diseases that are unrelated to elevated serum cholesterol levels, such as … …American Journal of Animal and Veterinary Sciences, Vol. 6, Issue 4 · 11 Jan 2012 · 7,679 accessesView PDFCite
Research ArticleOpen accessIn the keywordsThe Effect of S-Nitroso-N-Acetylpenicillamine and S-Nitroso-Captopril Co-Administered with Cysteine on Blood Glucose Concentration in an Animal ModelSacha Campbell, Ruby Alexander-Lindo, Tara Dasgupta et al.The study sought to test the hypothesis that co-administration of SNAP and cysteine or CapSNO and cysteine in normoglycaemic rats may further reduce glucose tolerance. An oral glucose tolerance was carried out and the plasma nitrite concentrations were measured and taken as the biochemical markers of in vivo NO formation. The results showed blood glucose levels were significantly elevated at … …American Journal of Biochemistry and Biotechnology, Vol. 4, Issue 3 · 31 Dec 2008 · 7,221 accessesView PDFCite
Research ArticleOpen accessIn the abstractAnti-Inflammatory Properties of Crude Extracts and Anti-Cancer Properties of Acetone Extract of Moringa Oleifera Lam. Flowers on Cell Line ModelsSandisiwe Maposa, Gloria Aderonke Otunola, Anthony Jide AfolayanIn recent times, Moringa oleifera has earned great interest for its various physiological and therapeutic benefits. Acetone, ethanol, methanol, and aqueous extracts of Moringa oleifera flowers were investigated for anti-inflammatory and anti-cancer potential. Anti-inflammatory capacity was evaluated using the inhibition of nitric oxide production (LPS-induced) on RAW 264.7, and cell viability was appraised with the MTT assay. The potential of … …American Journal of Biochemistry and Biotechnology, Vol. 22, Issue 1 · 15 Apr 2026 · 1,464 accessesView PDFCite
Research ArticleOpen accessIn the abstractInvestigation of Inflammatory and Oxidative Stress Biomarkers in Multi Vessels Minimally Invasive Coronary Artery Bypass Graft Surgery Versus Off-Pump Coronary Artery Bypass GraftMohammed Farouk Abdel-Hafez, Ahmed El-Minshawy, Ahmed M. Taha et al.Traditional Coronary Artery Bypass Graft (CABG) is currently among of the chief methods in dealing with patients suffering from atherosclerotic coronary heart disease. The current study aimed to measure and compare the levels of proinflammatory cytokines and oxidative stress marker in patients who underwent multivessels Minimally Invasive Coronary Artery Bypass Graft Surgery (MICS– CABG) versus off-pump Coronary Artery Bypass Grafting … …American Journal of Biochemistry and Biotechnology, Vol. 17, Issue 3 · 29 Sep 2021 · 6,170 accessesView PDFCite
Research ArticleOpen accessIn the abstractNumerical Simulation of Liquid Bio-Fuel Combustion in an EGR Equipped Micro Gas TurbineMaria Cristina Cameretti, Raffaele Tuccillo, Fabrizio Reale, Renzo PiazzesiThis paper focuses the attention to the possibility of a correct combustion close to the flameless regime, even in the presence of lower calorific value fuels like those that can be found with high concentrations in the bio-mass derived ones. In addition, the authors pay attention to the nitric oxide control by means of an optimal choice of the pilot … …American Journal of Applied Sciences, Vol. 12, Issue 7 · 4 Aug 2015 · 6,715 accessesView PDFCite
EditorialOpen accessIn the abstractThe Food Additives Nitrite and Nitrate and Microbiological Safety of Food ProductsStefanie Müller-Herbst, Anna Mühlig, Jan Kabisch et al.In Germany, raw sausages are typically produced according to a technology referred to as hurdle technology (Leistner, 2000). The combination of several stressful conditions should successfully inhibit growth and survival of pathogenic bacteria, which can be regularly found in raw pork or beef material (Mataragas et al., 2008; Rhoades et al., 2009). Hurdles applied during raw sausage fermentation are the … …Current Research in Microbiology, Vol. 6, Issue 1 · 29 Jun 2015 · 10,378 accessesView PDFCite