13 results for “Neurotoxicity”

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Research ArticleOpen accessIn the abstractQuercetin in Dimethyl Benzanthracene Induced Breast Cancer in RatsNatla Sashidhar Reddy, Parthasarathy Nirmala, Natesan Chidambaram, Pammi Ashok kumarProblem statement: Vincristine a commonly used anticancer agent in the treatment of breast cancer results in serious adverse effects like teratogenicity, neurotoxicity and carcinogenicity on long term use. Drug resistance is also a common problem encountered with vincristine. Hence the effect of flavonol quercetin, a known antioxidant with no known documented adverse effect was tried in treatment of DMBA induced … …American Journal of Pharmacology and Toxicology, Vol. 7, Issue 2 · 30 Jul 2012 · 8,138 accessesView PDF Cite

Research ArticleOpen accessIn the abstractThe Frequency of Polymorphisms affecting Lead and Mercury Toxicity among Children with AutismShannon Rose, Stepan Melnyk, Alena Savenka et al.Individual risk of developmental neurotoxicity with exposure to environmentally relevant levels of lead and mercury is likely to be determined by genetic susceptibility factors as well as additive interactions with other environmental pollutants, cumulative dose, and the developmental stage of exposure. The apparent increase in autism diagnosis over the last 15 years has enhanced interest in the possibility that an … …American Journal of Biochemistry and Biotechnology, Vol. 4, Issue 2 · 30 Jun 2008 · 7,521 accessesView PDF Cite

Research ArticleOpen accessIn the abstractNeuropsychological Dysfunction among HIV Infected Drug AbusersRamani S. Durvasula, Charles H. HinkinHuman immunodeficiency virus (HIV) has been documented to cause direct and indirect central nervous system dysfunction that can be observed as a progressive decline in neuropsychological functioning in a large proportion of persons with HIV and AIDS. Neuropsychological decline in individuals with HIV is characterized by cognitive and motor slowing, attentional deficits, executive dysfunction and memory impairment (characterized by intact … …American Journal of Infectious Diseases, Vol. 2, Issue 2 · 30 Jun 2006 · 7,155 accessesView PDF Cite