13 results for “Neuroprotection”

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Research ArticleOpen accessIn the abstractEffects of Melatonin in Prevention of Neuropathy in STZ-Induced Diabetic RatsNasser Zangiabadi, Vahid Sheibani, Majid Asadi-Shekaari et al.Problem statement: Diabetes mellitus occurs mainly with chronic polyneuropathy, and oxidative stress plays an important role in emergence of most neurologic and behavioral changes in diabetic patients. Many studies have focused on the beneficial effects of various antioxidants such as melatonin on diabetic neuropathy. The aim of this study is to evaluate the effect of melatonin in prevention of neuropathy … …American Journal of Pharmacology and Toxicology, Vol. 6, Issue 2 · 17 Sep 2011 · 9,358 accessesView PDF Cite

Research ArticleOpen accessIn the abstractNasal Administration of Quercetin Liposomes Modulate Cognitive Impairment and Inhibit Acetylcholinesterase Activity in HippocampusTerdthai Tong-Un, Supaporn Muchimapura, Wathita Phachonpai, Jintanaporn WattanathornProblem statement: Oxidative stress is a major factor implicated in the degeneration of cholinergic neurons in Alzheimer’s Disease (AD). Several reports have indicated that antioxidant intake is beneficial to delay or inhibit the progression of this disease. Presently, Acetylcholinesterase (AChE) inhibitors are the mainstay of therapy for AD. Quercetin, one of the flavonoids in fruits and vegetables, has a powerful … …Neuroscience International, Vol. 1, Issue 1 · 30 Jun 2010 · 7,170 accessesView PDF Cite

Research ArticleOpen accessIn the abstractNeuropsychological Consequences of HIV and Drug AuseArun Venkatesan, Ola Selnes, Valerie Wojna et al.Accurate assessment of the functional consequences of human immunodeficiency virus (HIV) infection and drugs of abuse are critical as large populations are afflicted with both. Both are interdependent epidemics with important socioeconomic consequences. Experimental studies in animal models and in vitro clearly indicate that HIV and drugs of abuse cause increased neurodegeneration, glial cell activation and enhanced HIV replication. Nevertheless, … …American Journal of Infectious Diseases, Vol. 2, Issue 2 · 30 Jun 2006 · 6,662 accessesView PDF Cite