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26 articles for “Malignant Tumor”
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EditorialOpen accessIn the abstractAre we Able to Harness the Immunomodulatory Power of Cytokines for Novel Autoimmune Disease Treatments?Giuseppe Nocentini, Graziella Migliorati, Carlo RiccardiSince the end of the 1970s, interleukin 2 (IL-2) has been known as a key player in T cell expansion/activation (Watson et al., 1980). In the late 1980s, some groups used IL-2 to stimulate the immune systems of tumour patients (Jacobs et al., 1986). The idea seemed brilliant and several attempts were made, but the results were disappointing (Lim et … …American Journal of Pharmacology and Toxicology, Vol. 10, Issue 2 · 22 Oct 2015 · 7,629 accessesView PDFCite
Research ArticleOpen accessIn the abstractGAUSSIAN MIXTURE MODEL BASED CLASSIFICATION OF MICROCALCIFICATION IN MAMMOGRAMS USING DYADIC WAVELET TRANSFORMSuman Mishra, Hariharan RanganathanBreast cancer is a serious health related issue for women in the world. Cancer detected at premature stages has a higher probability of being cured, whereas at advanced stages chances of survival are bleak. Screening programs aid in detecting potential breast cancer at early stages of the disease. Among the various screening programs, mammography is the proven standard for screening … …Journal of Computer Science, Vol. 9, Issue 10 · 5 Sep 2013 · 6,873 accessesView PDFCite
Research ArticleOpen accessIn the abstractTweaking Exponential Distribution to Estimate the Chance for More Survival Time if a Cancerous Kidney is RemovedRamalingam ShanmugamPatients with a malignant tumor in the kidney (recognized as hypernephroma in medical practice) are treated by what is known as nephrectomy (that is a surgical removal of the kidney) in addition to a combionation of chemotherapy and immunotherapy for the sake of more survival time. This articles develops and demonstrates a statistical methodology to assess the statistical significance of … …International Journal of Research in Nursing, Vol. 4, Issue 2 · 4 Sep 2013 · 6,222 accessesView PDFCite
Research ArticleOpen accessIn the abstractIMMUNOHISTOCHEMICAL ANALYSIS OF UROTHELIAL BLADDER CANCERSKatarina Bevizova, Jan Jakubovsky, Jan Luha et al.Malignant cancers of urinary bladder are the second most common malignancy of the urinary tract and the fourth most common malignancy in general, especially in men. The aim of this study was a retrospective analysis of selected markers (p53, Ki-67 and E-cadherin) of urinary bladder cancers from the Department of Urology in Bratislava, Slovak Republic between years 2007 and 2009. … …OnLine Journal of Biological Sciences, Vol. 13, Issue 2 · 17 Jul 2013 · 7,374 accessesView PDFCite
Research ArticleOpen accessIn the abstractNovel Fuzzy Technique for Cancer Detection in Noisy Breast Ultrasound ImagesN. Alamelumangai, J. DeviShreeProblem statement: Detecting tumor areas in breast Ultrasound (US) images is a challenging task. The occurrence of benign areas in breast may result in false identification of malignant areas which may have serious outcome. Approach: The CAD system could act as a major function in the early detection of breast cancer and could decrease the death rate among women with … …American Journal of Applied Sciences, Vol. 9, Issue 5 · 12 Mar 2012 · 6,963 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Impact of Air Pollution on Human Health: Focusing on the Rudnyi Altay Industrial AreaVitaliy G. Salnikov, Marat A. KaratayevProblem statement: Air pollution in Kazakhstan is significant environmental problem. The air pollution level of cities and industrial centers remains rather high. The highest level of air pollution is registered in Ridder, Ust-Kamenogorsk, Almaty, Zyryanovsk, Aktau, Atyrau, Shymkent, Taraz, Petropavlovsk and Temirtau. The enterprises of the Rudnyi Altay, Pavlodar Oblast and enterprises of oil and gas complex in West-Kazakhstan, Atyrau … …American Journal of Environmental Sciences, Vol. 7, Issue 3 · 21 Jul 2011 · 10,451 accessesView PDFCite
Research ArticleOpen accessIn the abstractRelationship Between Blood Fibrinogen Concentration and Pathological Features of Cancer Patients: A 139-case Clinical StudyDa-Yong Lu, Xue-Liang Chen, Min Huang et al.Angiogenesis and coagulation are among the most consistent host responses to the presence of a malignant tissue. Pathological angiogenesis and coagulation are often occurred in patients with solid tumors, especially in the occurrence of neoplasm metastasis and as targets for anti-metastatic drugs such as antiangiogenesis agents, coagulation-mediated agents and anticancer drugs. Since fibrinogen (Fib) is the most abundant and key … …OnLine Journal of Biological Sciences, Vol. 7, Issue 1 · 4 Sep 2010 · 7,871 accessesView PDFCite
Research ArticleOpen accessIn the abstractFeature Extraction for Characterization of Breast Lesions in Ultrasound Echography and ElastographyShirley Selvan, M. Kavitha, S. Shenbagadevi, S. SureshProblem statement: Elastography is developed as a quantitative approach to imaging linear elastic properties of tissues to detect suspicious tumors. We propose an automatic feature extraction method in ultrasound elastography and echography for characterization of breast lesions. Approach: The proposed algorithm was tested on 40 pairs of biopsy proven ultrasound elastography and echography images of which 11 are cystic, 16 … …Journal of Computer Science, Vol. 6, Issue 1 · 31 Jan 2010 · 8,320 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Tumor/Immune Interface: Clinical Evidence of Cancer Immunosurveillance, Immunoediting and ImmunosubversionMatthew S. Block, Svetomir N. MarkovicProblem statement: The interactions of a malignant tumor with the patient’s immune system are dynamic, multiple and bi-directional. Approach: This article reviews the clinical evidence of the interaction of cancer with immunity with emphasis on recent developments highlighting some of the mechanisms of tumor-mediated regulation of immunity. Results: Most of the time, the immune response to a malignancy acts to … …American Journal of Immunology, Vol. 5, Issue 1 · 31 Mar 2009 · 10,100 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Interplay between p53 and p21 Tumor Suppressor Proteins in the Transformation of Colorectal Adenoma to CarcinomaA.S. Abdulamir, R.R. Hafidh, L.K. Mahdi et al.This study was carried out for evaluating the interplay of p53, p21 and Ki-67 proteins along the colorectal adenoma-carcinoma oncogenic transformation sequel. Therefore, Fifty colorectal cancer and 14 adenoma patients were involved. The histopathological expression of p53, p21 and Ki-67 proteins was evaluated by immunohistochemistry assay. The results revealed that remarkable overexpression of p53 protein was seen in the tumorous … …American Journal of Immunology, Vol. 4, Issue 2 · 30 Jun 2008 · 7,742 accessesView PDFCite