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29 articles for “M. P. Jonathan”
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Case ReportOpen accessIn the author namesA Case of Phaeohyphomycosis Caused by Exophiala oligosperma in a Renal Transplant Patient Successfully Treated with PosaconazoleAsaph C Levy, Sameer Rehman, Deanna A Sutton et al.Phaeohyphomycosis is an uncommon mycotic infection caused by dematiaceous fungi. We report a 53-year-old male who presented with phaeohyphomycosis on his upper extremities, 6 months after renal transplantation. Biopsy revealed pigmented moniliform hyphae and cultures grew Exophiala oligosperma. The lesions completely resolved after 3 months of treatment with posaconazole. …American Journal of Infectious Diseases, Vol. 11, Issue 1 · 22 Jun 2015 · 8,032 accessesView PDFCite
Research ArticleOpen accessIn the author namesSynchrotron Powder Diffraction Study of Radiation Damage in Langmuir Blodgett Nanotemplate Crystallised ProteinJonathan P. Wright, Eugenia Pechkova, Claudio NicoliniPolycrystalline samples of lysozyme were prepared with and without a Langmuir-Blodgett (LB) thin film template via both the hanging drop method and batch crystallisation. Powder diffraction methods are used to compare these samples and to measure their resistance to radiation damage at room temperature. The X-ray induced amorphisation of the samples was followed as a function of time and it … …American Journal of Biochemistry and Biotechnology, Vol. 10, Issue 3 · 12 Nov 2014 · 8,177 accessesView PDFCite
Research ArticleOpen accessIn the author namesEFFECTS OF SUPPLEMENTAL LYSINE ON PERFORMANCE, ANTIBODY TITER AND RECTAL TEMPERATURE IN RESPONSE TO A MODIFIED-LIVE VIRAL VACCINE IN NEONATAL CALVESKate Sharon, Glenn Duff, Jeff Dailey et al.Infectious Bovine Rhinotracheitis (IBR), caused by bovine herpesvirus-1, contributes significantly to economic losses in the dairy and beef cattle industry. Lysine has been shown reduce virulence of herpesviruses in felids and humans. Our objective was to evaluate the effects of supplemental lysine on serum IBR antibody titer and rectal temperature in response to a modified-live Intranasal (IN) or Intramuscular (IM) … …American Journal of Animal and Veterinary Sciences, Vol. 9, Issue 2 · 2 Jun 2014 · 7,609 accessesView PDFCite
Research ArticleOpen accessIn the author namesA SHORT INTERFERING RNA MOLECULAR BEACON FOR THE ATTENUATION OF MYCOBACTERIAL INFECTIONRemo George, Kathy Nugent, Norman Bolus et al.The ability of the pathogen Mycobacterium Tuberculosis (MTB) to invade and survive within macrophages of granulomas is attributed to the product of the Mammalian Cell Entry (MCE) operon whose gene, mce4A, encodes a cholesterol transporter that transports host lipids into the bacterium that allows the bacterium to survive during chronic infection. Here, we proposed and tested the hypothesis that a … …American Journal of Biochemistry and Biotechnology, Vol. 10, Issue 1 · 4 Mar 2014 · 7,776 accessesView PDFCite
Research ArticleOpen accessIn the author namesFREE ENERGY MEASUREMENT DISTINGUISHES NORMAL FROM CANCER CELL, OFFERING A NEW PERSPECTIVE FOR CURING CANCERKambiz Afrasiabi, Jonathan Melekh-ShalomThe interplay of the second law of thermodynamics with the normal state and the methodology needed for the measurement of free energy of normal and malignant cells and its practical implications has not been clearly addressed in current literature. The second law of thermodynamics is one of the most fundamental laws governing the known universe at all levels. A normal … …OnLine Journal of Biological Sciences, Vol. 13, Issue 4 · 12 Oct 2013 · 7,227 accessesView PDFCite
Research ArticleOpen accessIn the author namesStructural Consequences of the Polymorphism Q223R in the Human Leptin Receptor: A Molecular Dynamics StudyJonathan P. Carrillo-Vázquez, Brenda Chimal-Vega, Beatriz Zamora-López et al.Leptin Receptor (LEPR) is a component of a signaling pathway related to appetite and energy expenditure. Single Nucleotide Polymorphisms (SNP) of Leptin receptor gene (lepr) have been proposed as possible modulator of adipose tissue and body weight. The main phenomenological consequence reported of these SNPs is the modulation of the LEP-LEPR interaction promoting the weight gain. Particularly, Q223R polymorphism has … …American Journal of Agricultural and Biological Sciences, Vol. 8, Issue 3 · 23 Sep 2013 · 7,839 accessesView PDFCite
Research ArticleOpen accessIn the author namesHYPOXIC INFLAMMATION, A DEADLY BRIDGE TO MALIGNANT TRANSFORMATION AND A FERTILE SOIL FOR CANCER PREVENTIONKambiz Afrasiabi, Robert Edwards, Jonathan Melekh-Shalom, Kehui WangThe interplay of the inflammatory microenvironment with its hypoxic niche and the potential mechanism by which they lead to malignant transformation has long been the subject of great controversy and continues to be an area of great interest today. In our previous studies we have examined this subject by using Gia2 knock out mice as the focus of our research. … …OnLine Journal of Biological Sciences, Vol. 13, Issue 3 · 4 Sep 2013 · 7,149 accessesView PDFCite
Research ArticleOpen accessIn the author namesIdentification of Pharmacological Targets Combining Docking and Molecular Dynamics SimulationsIlizaliturri-Flores Ian, Rosas-Trigueros Jorge Luis, Carrillo-Vazquez Jonathan Pablo et al.Studies that include both experimental data and computational simulations (in silico) have increased in number because the techniques are complementary. In silico methodologies are currently an essential component of drug design; moreover, identification and optimization of the best ligand based on the structures of biomolecules are common scientific challenges. Geometric structural properties of biomolecules explain their behavior and interactions and … …American Journal of Agricultural and Biological Sciences, Vol. 8, Issue 1 · 21 Mar 2013 · 8,130 accessesView PDFCite
Research ArticleOpen accessIn the author namesG-2548A Leptin Promoter and Q223R Leptin Receptor Polymorphisms in Obese Mexican SubjectsP. Carrillo-Vazquez Jonathan, Lopez-Alcantar Jeronimo, Chimal-Vega Brenda et al.Leptin interaction with its receptor in the hypothalamus stimulates a specific signaling cascade that results in the synthesis of anorexigenic and orexigenic peptides in order to regulate food intake and energy expenditure. Many polymorphisms in leptin (lep) and leptin receptor (lepr) genes have been associated with body weight. In particular, G-2548A in the lep promoter and Q223R in lepr variants … …American Journal of Agricultural and Biological Sciences, Vol. 8, Issue 1 · 12 Feb 2013 · 8,645 accessesView PDFCite
Research ArticleOpen accessIn the author namesHeavy Metals Contamination of Road-Deposited SedimentsJonathan YisaProblem statement: Impact of anthropogenic activities on man and his environment as a result of the growing rate of urbanization in Bida, Nigeria is of a great concern. Street sediments that accumulate along pavements in urban environments have the potential to provide considerable loadings of heavy metals to receiving waters and water bodies, particularly with changing environmental conditions. The objective … …American Journal of Applied Sciences, Vol. 7, Issue 9 · 30 Sep 2010 · 7,314 accessesView PDFCite