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28 articles for “M. Lakshmi”
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Research ArticleOpen accessIn the author namesDiscovery of Evolutionary Divergence of Biological Nitrogen Fixation and Photosynthesis: Fine Tuning of Biogenesis of the NifH and the ChlL by a Peptidyl-Prolyl Cis/Trans IsomeraseNara Gavini, Sinny Delacroix, Kelvin Harris Jr., Lakshmi PulakatProblem statement: Despite the structural and functional similarities between the nitrogenase that performs biological nitrogen fixation reaction and the Dark Protochlorphyllide Oxidoreductase (DPOR) that performs chlorophyll-biosynthesis, attempts to substitute nitrogenase-components with DPOR-components have hitherto failed. This investigation was undertaken to test if Chlamydomonas reinhardtii protochlorophyllide (Pchlide) reductase (ChlL) that shares some structural similarity with Nitrogenase Reductase (NifH) could complement the … …American Journal of Biochemistry and Biotechnology, Vol. 7, Issue 4 · 17 Feb 2012 · 7,620 accessesView PDFCite
Research ArticleOpen accessIn the author namesWavelet Analysis and Orthogonal Moments based Classification of Microcalcification in Digital MammogramsN. V.S. Sree Rathna Lakshmi, C. ManoharanProblem statement: An important early sign of breast cancer is the clusters of micro calcifications in digital mammograms. To assist radiologists in the diagnosis of mammographic clusters a novel hybrid algorithm has been developed. Approach: A method, for detecting micro calcification in mammograms based on combined feature set with Ant Colony Optimization (ACO) was proposed. The diagonal matrix ‘S’ obtained … …Journal of Computer Science, Vol. 7, Issue 10 · 6 Aug 2011 · 6,562 accessesView PDFCite
Research ArticleOpen accessIn the author namesComposite Pseudo Associative Cache with Victim Cache for Mobile ProcessorsLakshmi Deepika Bobbala, Monobrata Debnath, Byeong Kil LeeProblem statement: Multi-core trends are becoming dominant, creating sophisticated and complicated cache structures. One of the easiest ways to design cache memory for increasing performance is to double the cache size. The big cache size is directly related to the area and power consumption. Especially in mobile processors, simple increase of the cache size may significantly affect its chip area … …Journal of Computer Science, Vol. 7, Issue 10 · 4 Aug 2011 · 7,090 accessesView PDFCite
Research ArticleOpen accessIn the author namesDesign and Analysis of Adders using Nanotechnology Based Quantum dot Cellular AutomataS. Karthigai Lakshmi, G. AthishaProblem statement: The area and complexity are the major issues in circuit design. Here, we propose different types of adder designs based on Quantum dot Cellular Automata (QCA) that reduces number of QCA cells and area compare to previous designs. The quantum dot cellular automata is a novel computing paradigm in nanotechnology that can implement digital circuits with faster speed, … …Journal of Computer Science, Vol. 7, Issue 7 · 30 Jun 2011 · 7,316 accessesView PDFCite
Research ArticleOpen accessIn the author namesHuman Behavior Classification Using Multi-Class Relevance Vector MachineB. Yogameena, S. Veera Lakshmi, M. Archana, S. Raju AbhaikumarProblem statement: In computer vision and robotics, one of the typical tasks is to identify specific objects in an image and to determine each object’s position and orientation relative to coordinate system. This study presented a Multi-class Relevance Vector machine (RVM) classification algorithm which classifies different human poses from a single stationary camera for video surveillance applications. Approach: First the … …Journal of Computer Science, Vol. 6, Issue 9 · 30 Sep 2010 · 7,396 accessesView PDFCite
Research ArticleOpen accessIn the author namesBoosting Kernel Discriminative Common Vectors for Face RecognitionC. Lakshmi, M. PonnavaikkoProblem statement: Kernel discriminative common vector (KDCV) was one of the most effective non-linear techniques for feature extraction from high dimensional data including images and text data. Approach: This study presented a new algorithm called Boosting Kernel Discriminative Common Vector (BKDCV) to further improve the overall performance of KDCV by integrating the boosting and KDCV techniques. Results: In BKDCV, the … …Journal of Computer Science, Vol. 5, Issue 11 · 30 Nov 2009 · 6,579 accessesView PDFCite
Research ArticleOpen accessIn the author namesTransgenic Indian Cotton (Gossypium hirsutum) Harboring Rice Chitinase Gene (Chi II) Confers Resistance to Two Fungal PathogensM. Ganesan, P. Bhanumathi, K. Ganesh Kumari et al.Problem statement: The present investigation described a simple and reproducible protocol for transgenic cotton regeneration and characterization of chitinase (Chi II) gene expression against two different fungal pathogens in cotton. Approach: Transgenic cotton (Gossypium hirsutum cv. SVPR2) plants were produced by pCambia-bar-Chi II (13.8 kb) under the control of the CaMV 35S promoter, harbored in the strain LBA 4404 Agrobacterium … …American Journal of Biochemistry and Biotechnology, Vol. 5, Issue 2 · 30 Jun 2009 · 8,536 accessesView PDFCite
Research ArticleOpen accessIn the author namesNifH: Structural and Mechanistic Similarities with Proteins Involved in Diverse Biological ProcessesSurobhi Lahiri, Lakshmi Pulakat, Nara GaviniThe NifH protein is a subunit of the nitrogenase enzyme that catalyzes the reduction of atmospheric nitrogen to ammonia. This protein contains highly conserved regions including the nucleotide binding sites, metal center ligands and the Switch I and Switch II domains. A number of proteins have structural and mechanistic similarities as well as evolutionary relationships with the NifH protein, notable … …American Journal of Biochemistry and Biotechnology, Vol. 4, Issue 3 · 30 Sep 2008 · 6,674 accessesView PDFCite
Research ArticleOpen accessIn the author namesAT1-IR-beta Association: A New Mechanism for the Inhibition of Insulin Receptor Function in Breast CancerLakshmi Pulakat, Ravindra Kolhe, Nara GaviniEpidemiological evidence show that increased mortality in breast cancer is linked to hypertension and insulin resistance. Because Angiotensin II (Ang II), a hormone implicated in hypertension and insulin resistance, is a normal mitogen for breast tissue and elevated expression of the Ang II receptor AT1 is seen in breast cancer, we analyzed the effects of Ang II exposure on the … …American Journal of Biochemistry and Biotechnology, Vol. 4, Issue 1 · 31 Mar 2008 · 7,019 accessesView PDFCite
Research ArticleOpen accessIn the author namesThe NifX Protein is Involved in the Final Stages of FeMo-cofactor Transport to the MoFe ProteinSurobhi Lahiri, Byron Cole, Lakshmi Pulakat, Nara GaviniThe nitrogenase enzyme catalyzes the reduction of dinitrogen to ammonia and is composed of the Fe and MoFe proteins. The iron molybdenum cofactor (FeMo-co) of the MoFe protein is the site of active substrate reduction. The NifX protein has also been suggested to have a role in the FeMo-co synthesis, although its exact role is still open to investigation. We … …American Journal of Biochemistry and Biotechnology, Vol. 3, Issue 2 · 30 Jun 2007 · 7,264 accessesView PDFCite