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34 results for “Liver Analysis”

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Research ArticleOpen accessIn the abstractABSENCE OF VISIBLE TOXIC EFFECTS ACCOMPANYING THE SHORT-TERM ADMINISTRATION OF AN AQUEOUS EXTRACT OF ALLIUM SATIVA LINN. IN MALE SPRAGUE-DAWLEY RATSJ. Asiedu-Gyekye Isaac, Awortwe Charles, A. Antwi DanielAllium sativum is cultivated in the northern part of Ghana and has gained widespread use as chemoprotective, in curing hypertension, impotence and erectile dysfunction. The multipurpose use together with its aphrodisiac activity has resulted in the widespread use of this plant medicine both in meals and as herbal medications. Safety assessment of this plant however is rare. The present study … …American Journal of Pharmacology and Toxicology, Vol. 9, Issue 1 · 30 Jan 2014 · 7,577 accessesView PDFCite
Research ArticleOpen accessIn the abstractSPECTRAL DOMAIN FEATURES FOR OVARIAN CANCER DATA ANALYSISAhmed Farag Seddik, Riham Amin Hassan, Mahmoud A. FakhreldeinThe early detection of cancer is crucial for successful treatment. Medical researchers have investigated a number of early-diagnosis techniques. Recently, they have discovered that some cancers affect the concentration of certain molecules in the blood, which allows early diagnosis by analyzing the blood mass spectrum. Researchers have developed several techniques for the analysis of the mass-spectrum curve analysis and used … …Journal of Computer Science, Vol. 9, Issue 8 · 9 Jul 2013 · 6,915 accessesView PDFCite
Research ArticleOpen accessIn the abstractConcentration-Effect, Incidence and Mechanism of Nevirapine HepatotoxicityAdikwu Elias, Brambaifa NelsonNevirapine is a dipyridozepinone non nucleoside reverse transcriptase inhibitor approved for use in HIV-infected patients. Its efficacy has been well demonstrated in numerous clinical trials. It has activity against HIV-1 but does not have significant activity against HIV-2 or other retroviruses. Nevirapine is used as one of the components of highly active antiretroviral therapy in HIV patients and in the … …American Journal of Pharmacology and Toxicology, Vol. 8, Issue 1 · 19 Apr 2013 · 8,156 accessesView PDFCite
Research ArticleOpen accessIn the abstractGastroprotective Effect and Safety Assessment of Zanthoxylum Zanthoxyloides (Lam) Waterm Root Bark ExtractAlex Boye, George Asumeng Koffuor, Johnson Nyarko Boampong et al.Problem statement: Gastrointestinal ulcers account significantly for morbidity and mortality in Ghana. The study therefore investigated the gastroprotective effect of an ethanolic root bark extract of Zanthoxylum zanthxyloides and its safety for us. Approach: Gastric ulceration was induced in Sprague-Dawley rats with Indomethacin (25 mg kg-1, p.o) and was treated with 150, 250, or 500 mg kg-1 of the extract, … …American Journal of Pharmacology and Toxicology, Vol. 7, Issue 2 · 7 Aug 2012 · 8,495 accessesView PDFCite
Research ArticleOpen accessIn the abstractOccupational Exposure of Pesticides on Activities of Alanine aminotransferase and γ-Glutamyltranspeptidase in Blood among Vegetables FarmersShamsul Bahari Shamsudin, T. Hang YapProblem statement: Most vegetable farmers are using agricultural chemicals on their farms. Many of these chemicals are used to control pests and are known as pesticides. Pesticides can be considered according to their chemical basis. Most of the more toxic pesticides fall into chemical groups of organophosphates, carbamates and bipyridyls. Approach: The general objective to study the level of liver … …Current Research in Medicine, Vol. 2, Issue 2 · 4 Oct 2011 · 7,938 accessesView PDFCite
Research ArticleOpen accessIn the abstractMetals Concentrations in Tissues of Tilapia gallier, Crarias lazera and Osteoglossidae Caught from Alau Dam, Maiduguri, Borno State, NigeriaG.A. Dimari, F.I. Abdulrahman, J.C. Akan, S.T. GarbaAn analysis of intestine, liver, stomach and gill tissue concentrations of heavy metals (Cu, Co, Pb, Cr, Mn, Fe, Ni, Cd and Zn) in three commercially important fish species (Tilapia gallier, Crarias lazera and Osteoglossidae. caught within Alau Dam between the periods of January to August, 2007. These heavy metals were determined using Perkin-Elmer AAnalyst 300 Atomic Absorption Spectroscopy (AAS). … …American Journal of Environmental Sciences, Vol. 4, Issue 4 · 31 Aug 2008 · 7,485 accessesView PDFCite
Research ArticleOpen accessIn the abstractUltrastructural Evidences of Hepatitis B Infection in Human Liver Biopsies Disclose Complex Assembly and Morphogenesis Pathways for Hepatitis B VirusViviana Falcon, Ivon Menéndez, Nelson Acosta-Rivero et al.Despite of recent advances on acknowledge of hepatitis B virus (HBV) structure and biology, little is known about the morphogenesis and release of virions. In this study, the ultrastructural analysis of HBV components in liver biopsies from chronically HBV-infected patients disclosed complex assembly and morphogenesis pathways for HBV. HBV core (HBcAg) and surface (HBsAg) antigens were specifically identified in all … …American Journal of Infectious Diseases, Vol. 4, Issue 2 · 30 Jun 2008 · 7,091 accessesView PDFCite
Research ArticleOpen accessIn the abstractSubacute Toxicity of Crocus Sativus L. (Saffron) Stigma Ethanolic Extract in RatsDaryoush Mohajeri, Ghafour Mousavi, Mehran Mesgari et al.The medicinal properties attributed to Crocus sativus L. (saffron) are extensive. The safety of saffron is important in relation to its medicinal applications. This study was performed to elucidate the possible toxic effects of ethanolic extract of Crocus sativus L. stigma on liver, kidney and some hematological parameters in rats. Wistar rats were randomly assigned into four groups of eight … …American Journal of Pharmacology and Toxicology, Vol. 2, Issue 4 · 31 Dec 2007 · 8,562 accessesView PDFCite
Research ArticleOpen accessIn the abstractEvidences of Apoptosis in Hepatitis C Virus-Infected Hepatocytes and Peripheral Blood Monocuclear Cells in the Absence of Liver InjuryViviana Falcón, Nelson Acosta-Rivero, Mineko Shibayama et al.Understanding the mechanism of Hepatitis C Virus (HCV) pathogenesis is an important part of HCV research. In this study, the presence of apoptosis in HCV-infected liver and Peripheral Blood Mononuclear Cells (PBMC) from patients positive for anti-HCV antibodies and negative for serum HCV-RNA was investigated. The samples obtained from 21 patients were studied by in situ Hybridization (ISH), Immunofluorescence, TUNEL … …American Journal of Infectious Diseases, Vol. 1, Issue 1 · 31 Mar 2005 · 6,975 accessesView PDFCite
Research ArticleOpen accessIn the abstractDetection of HCV Components and Pathological Reactions in Apoptotic Hepatocytes from Chronically HCV-infected PatientsViviana Falcón, Nelson Acosta-Rivero, Mineko Shibayama et al.Analysis of Hepatitis C Virus (HCV)-infected hepatocytes at the cellular level may contribute to elucidate the mechanisms of HCV pathogenesis. In this work, the presence of HCV components and pathological reactions in apoptotic hepatocytes from chronic HCV-infected patients were studied by electron microscopy and confocal microscopy. Eight samples of liver biopsies from patients with chronic hepatitis C were studied by … …American Journal of Infectious Diseases, Vol. 1, Issue 1 · 31 Mar 2005 · 6,907 accessesView PDFCite