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32 articles for “Leukocyte”
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Research ArticleOpen accessIn the keywordsCo-Inhibitory Molecule Programmed Death-1 and its Ligands: A New Alternative Therapy for Human Immunodeficiency Virus Infection?A. Leon-Flores, P. Del Rio, G. Reyes-TeranChronic viral infections are characterized by the up-regulation of a set of immunomodulatory receptors. The over-expression of co-inhibitory molecules on T cells leads to a dysfunctional T cell response with an "exhausted" phenotype. Programmed Death-1 (PD-1) is a molecule that exerts an inhibitory signal on the T cell receptor when it binds to the PD-L1 or PD-L2 ligands present on … …American Journal of Infectious Diseases, Vol. 8, Issue 4 · 28 Dec 2012 · 6,965 accessesView PDFCite
Research ArticleOpen accessIn the abstractEfficacy of Murraya paniculata Leaf Flour in Reducing Subclinical Mastitis in Dairy Goats Fed Date Pulp-Based DietsDwierra Evvyernie, Endah Yuniarti, Rika Zahera, Anuraga JayanegaraSubclinical mastitis is a major concern in dairy production, leading to economic losses and antibiotic dependence, which poses risks of milk residue contamination. As a natural alternative, orange jasmine (Murraya paniculata) leaves, rich in flavonoids, exhibit antimicrobial and anti-inflammatory properties. This study investigated the effects of incorporating date pulp and orange jasmine leaf flour (OLF) into the diets of lactating … …American Journal of Animal and Veterinary Sciences, Vol. 20, Issue 4 · 21 Feb 2026 · 1,598 accessesView PDFCite
Research ArticleOpen accessIn the abstractAnalysis of the Cytogenetic Status, Genome Instability, and Adaptive Potential of the Kazakh Tobet DogOksana Cherednichenko, Anastassiya Pilyugina, Dinara Azizbekova et al.In recent years, interest in indigenous dog breeds has increased. The Tobet is a unique breed of Kazakh livestock guardian dogs adapted to nomadic pastoralism that developed over thousands of years across Central Asia and Turkestan. Currently, the Tobet breed faces critical endangerment. Its conservation and sustainable breeding require thorough analysis of hereditary characteristics, genome stability, and adaptive potential. In … …American Journal of Animal and Veterinary Sciences, Vol. 20, Issue 4 · 19 Feb 2026 · 1,896 accessesView PDFCite
Research ArticleOpen accessIn the abstractEnhanced Immunity of Hybrid Grouper (Epinephelus sp.) Against Viral Nervous Necrosis Using a Recombinant Protein Nanovaccine from Chlorella VulgarisUun Yanuhar, Herly Evanuarini, Heru Suryanto et al.Hybrid Grouper (Epinephelus sp.) is an important export commodity in marine aquaculture, yet Viral Nervous Necrosis (VNN) remains a major threat. Nanovaccines are a type of vaccine developed by combining vaccine ingredients with silver nanoparticles and recombinant protein from Chlorella vulgaris. These formulations are designed to effectively boost the body's immune system response to prevent disease infection and destroy pathogenic … …OnLine Journal of Biological Sciences, Vol. 25, Issue 3 · 22 Nov 2025 · 2,156 accessesView PDFCite
Research ArticleOpen accessIn the abstractPharmacological Properties of Bioactive Extracts from the Rhizome of Aristolochia longa LAmal El Hamsas El Youbi, Dalila BoustaAristolochia longa is a medicinal plant well known in Moroccan folk medicine for its activity against constipation, intestinal infections and skin diseases. The present study was performed to evaluate in vitro and in vivo immunomodulatory and cytotoxic activities of aqueous and protein extracts of A. longa. The in vitro immunomodulatory results showed that aqueous extract at 0.1 mg/mL enhanced T-lymphocyte … …American Journal of Pharmacology and Toxicology, Vol. 15, Issue 1 · 21 Jul 2020 · 7,459 accessesView PDFCite
Research ArticleOpen accessIn the abstractSafety Assessment of Indigenous Probiotic Strain Lactobacillus plantarum Dad-13 Isolated from Dadih Using Sprague Dawley Rats as a ModelEndang S Rahayu, Ilzamha H Rusdan, Armita Athennia et al.Lactobacillus plantarum Dad-13 is a probiotic candidate from dadih, a traditional fermented buffalo milk from West Sumatera, Indonesia. This study aimed to evaluate safety aspects of L. plantarum Dad-13 in high dose consumption on Sprague Dawley rats. Two treatment groups were fed with 1011 CFU/mL/day of L. plantarum Dad-13 for 14 and 28 days respectively. Two placebo groups were fed … …American Journal of Pharmacology and Toxicology, Vol. 14, Issue 1 · 12 Nov 2019 · 10,142 accessesView PDFCite
Research ArticleOpen accessIn the abstractProducts of Solid-Phase Probiotic Bacilli Fermentation Increase Food Conversion Efficiency and Stimulate Chicken GrowthMazanko Maria S., Aleksandr I. Klimenko, Ivan F. Gorlov et al.Poultry farming is one of the major directions in agriculture. Agricultural poultry has high growth speed, productivity and is resistant to the industrial environment. Our group carried out a study of probiotic preparations of Bacillus subtilis KATMIRA1933 and Bacillus amyloliquefaciens B-1895 strains. These preparations were made by solid-phase fermentation and tested for dynamical germination of rearing flock (Highsex brown). The … …American Journal of Biochemistry and Biotechnology, Vol. 14, Issue 4 · 4 Dec 2018 · 9,379 accessesView PDFCite
Research ArticleOpen accessIn the abstractRelationship Between Antibodies to Toxocara and the Disability of the Human Ankylosing SpondylitisFrancisco-Javier Jiménez-Balderas, Patricia Méndez-Samperio, Raquel Tapia-Romero, Jorge-Luis de-la-Rosa-AranaThere are only few studies reported in the literature of patients with spondyloarthropathies associated with Toxocara infection. Thus, the aim of this work was to investigate the relationship between antibodies to Toxocara and the disability of the human Ankylosing Spondylitis (AS). Thirty-six AS patients (14 female and 22 male) participated during the study period and all were residents from Mexico … …American Journal of Infectious Diseases, Vol. 11, Issue 1 · 29 May 2015 · 6,891 accessesView PDFCite
EditorialOpen accessIn the abstractNeutrophil Extracellular Traps as Therapeutic Targets for Inflammatory DiseaseRory R. KoenenNeutrophilic granulocytes, or neutrophils are the most abundant circulating white blood cell and constitute a first line of defense against pathogens. They are characterized by a large polymorphic lobular nucleus and the presence of many secretory granules in their cytoplasm. Neutrophils are essential for a functional host defense, as is evidenced by the occurrence of severe infections in individuals with … …American Journal of Pharmacology and Toxicology, Vol. 9, Issue 4 · 25 Feb 2015 · 8,740 accessesView PDFCite
Research ArticleOpen accessIn the abstractEXPOSURE TO SWINE HOUSING DUST MODULATES MACROPHAGE MORPHOLOGY AND FUNCTIONRuth J. Pender, Radiah C. Minor, Steven L. Hurley et al.Swine Confinement Facility (SCF) dust consists of a complex mixture of feed grain particles, bacterial components, organic particulates and gases. When these particles are inhaled they deposit along the respiratory tract and mediate respiratory symptoms and disease in swine farmers and facility workers. Macrophages ingest and eliminate microbes and debris under chronic conditions; however, the role of macrophages in agricultural-related … …American Journal of Immunology, Vol. 10, Issue 1 · 25 Mar 2014 · 7,609 accessesView PDFCite