13 articles for “Leptin”

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Research ArticleOpen accessIn the abstractEFFECTS OF MELANOCORTIN-4 RECEPTOR GENE ON GROWTH AND MEAT TRAITS IN PIGS RAISED IN RUSSIAA. Klimenko, A. Usatov, Lyubov Getmantseva et al.The Melanocortin-4 Receptor (MC4R), a G-protein coupled receptor, is implicated in mediating the effect of leptin on food intake and energy balance. A previous candidate gene study reported an association between an MC4R polymorphism (Asp298Asn) and growth and meat productive traits of pigs. The aim of this work was to determine frequencies of the MC4R/Taq I genotypes and alleles in … …American Journal of Agricultural and Biological Sciences, Vol. 9, Issue 2 · 11 Feb 2014 · 7,608 accessesView PDF Cite

Research ArticleOpen accessIn the abstractAdiponectin Regulation in Type 2 Diabetic Rats: Effects of Insulin, Metformin and DexamethasoneTamer Ahmed Ismail, Mohamed Mohamed Soliman, Shimaa Ahmed IsmailAdiponectin is a protein synthesized from adipose tissue, increases peripheral glucose utilization in liver and skeletal muscle. Adiponectin expression and secretion are decreased during obesity and insulin resistance. In this study, the effect of insulin, metformin and dexamethasone on serum lipid profiles was examined in Type 2 Diabetic (T2D) rats. T2D was induced by feeding rats a high fat diet … …American Journal of Pharmacology and Toxicology, Vol. 8, Issue 4 · 23 Nov 2013 · 7,723 accessesView PDF Cite

Research ArticleOpen accessIn the abstractBiochemical Alterations Induced by Amylin in Wistar RatsMohamed Mohamed Soliman, Zein Shaban IbrahimAmylin is a peptide hormone synthesized in β cells of pancreas together with insulin in response to glucose and nutrients. Amylin controls food intake and body weight but the exact mechanism is still unknown. This study aimed to examine the effects of amylin injection on hormones, metabolites and cytokines expression in rats. Wistar rats were injected amylin Intraperitoneally (IP) (10 … …American Journal of Pharmacology and Toxicology, Vol. 8, Issue 2 · 7 Jun 2013 · 6,767 accessesView PDF Cite