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21 articles for “Leishmania”
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Research ArticleOpen accessEvery word in the titleNEWER DRUGS FOR VISCERAL LEISHMANIASIS: A REVIEWKrishna Pandey, Dharmendra Singh, Sanjiva Bimal et al.Visceral Leishmaniasis (VL) is one of the most neglected tropical diseases worldwide. The diagnosis and treatment of this disease is quite complex. Sodium Antimony Gluconate (SAG) which used to be a very effective treatment has now developed resistance and is potentially a cardio-toxic drug. Pentamidine has now been discarded because of adverse effect of diabetes mellitus. Amphotericin-B is an effective … …American Journal of Infectious Diseases, Vol. 10, Issue 2 · 5 May 2014 · 7,135 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleEpidemiological Survey of Visceral Leishmaniasis: An Evidence Based ReportMohammad Arif Khan, Ravada Vinay Kumar, Krishna Pandey et al.The aim of this study was to find out the epidemiology of visceral leishmaniasis among individuals of different age group and sex living in rural communities of Bihar, India. A retrospective study was conducted on 133 patients with a history of prolong fever and weight loss who was admitted at Rajendra Memorial Research Institute Of Medical Sciences (RMRIMS), Patna, India … …American Journal of Infectious Diseases, Vol. 9, Issue 2 · 29 Jul 2013 · 7,538 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleModeling and Molecular Docking Studies on Rnase Aspergillus niger and Leishmania donovani Actin: Antileishmanial ActivityRavi Kumar Gundampati, Shraddha Sahu, Kirti Shila Sonkar et al.A.niger Rnase was designed from ACTBIND (PDB ID: 3D3Z). Yeast actin-human gelsolin segment 1 complex (PDB ID: 1YAG) was used as template for L. donovani actin protein for 3D model in Modeller9v8. These models were testified by PROCHECK, ERRAT, WHAT-IF, PROSA2003 and VERIFY-3D. All evidences suggest that the geometric quality of the backbone conformation, energy profile, residue interaction and contact … …American Journal of Biochemistry and Biotechnology, Vol. 9, Issue 3 · 21 Sep 2013 · 7,530 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleMolecular Identification of Leishmania Species in Patient with Cutaneous Leishmaniasis in an Endemic Area of Fars Province, Southern IranVahid Rahmanian, Nader Sharifi, Zahra Kargar Jahromi et al.The Cutaneous Leishmaniasis (CL) contains a range of factors, which provide different patterns of transmission that make it difficult to control. The aim of this study was to identify the different species of Leishmania in the Jahrom district of Fars province, southern Iran. This descriptive study was done on CL suspected cases who were referential to the Reference of Jahrom … …American Journal of Animal and Veterinary Sciences, Vol. 16, Issue 2 · 2 Apr 2021 · 6,946 accessesView PDFCite
Research ArticleOpen accessEvery word in the titlePOST KALA-AZAR DERMAL LEISHMANIASIS WITH ULCERATION ON FOOT: AN ATYPICAL CASE PRESENTATION SUCCESSFULLY TREATED WITH MILTEFOSINEVidyanand Rabi Das, Dharmendra Singh, Krishna Murti et al.Visceral Leishmaniasis (VL) or Kala-Azar (KA) is highly endemic in the Indian subcontinent particularly in Bihar. Post Kala-azar Dermal Leishmaniasis (PKDL) is a known reservoir for leishmania parasites for transmission of VL. The kala-azar elimination program was launched by the government of three countries of the Indian subcontinent in the year 2005, which aims to eliminate kala-azar by 2015 and … …American Journal of Infectious Diseases, Vol. 10, Issue 2 · 2 Apr 2014 · 7,586 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleOverdominance Effects between Malaria and Visceral Leishmaniasis in the 5q31 RegionMutaz Amin, Abdelbadea Elhassan, Kirk Rocket, Muntasir IbrahimA group of SNPs in 5q31, genotyped from Hausa tribe of Koka village in eastern Sudan; an area endemic with malaria and visceral leishmaniasis, were analyzed by The Leishmaniasis research group and found to have significant excess of heterozygosis level and departure from HWE and assumed to be due to natural selection resulting from notorious deadly outbreaks since various ethnic … …OnLine Journal of Biological Sciences, Vol. 15, Issue 4 · 18 Sep 2015 · 7,119 accessesView PDFCite
HypothesisOpen accessIn the keywordsNatural Substances as New Potential Strategies for the Treatment of Leishmaniosisin DogsDe Vito Virginia, Helen Owen, Amnart Poapolathep, Giorgi MarioLeishmaniasis is a disease caused by the protozoan parasites Leishmania, infecting numerous mammal species. Canine leishmaniasis is potentially zoonotic and causes severe fatal disease in dogs. The discovery of new natural products extracted from medicinal plants or compounds derived from them, such as quercetin, hesperidin, vitamin c, horse chestnut extract and selenium could represent a valuable source of new medicinal … …American Journal of Animal and Veterinary Sciences, Vol. 12, Issue 3 · 6 Sep 2017 · 8,862 accessesView PDFCite
Research ArticleOpen accessIn the keywordsIn Silico and in Vitro Studies: Tryparedoxin Peroxidase Inhibitor Activity of Methotrexate for Antileishmanial ActivityRavi Kumar Gundampati, Shraddha Sahu, Avinash Kumar Srivastava et al.In order to understand the mechanism of molecular interactions at the active site of Tryparedoxin Peroxidase (Try P), homology modeling and docking studies were performed. We generated a Three-Dimensional (3D) model of target protein based on the Crystal structure of Leishmania Major Try PI (PDB ID: 3TUE) using modeler software. Docking analysis was carried out to study the effects of … …American Journal of Infectious Diseases, Vol. 9, Issue 4 · 28 Nov 2013 · 7,894 accessesView PDFCite
Research ArticleOpen accessIn the keywordsRETRACTED: Evaluation of the Cytotoxic Activity of Aqueous Extract of Schinus terebinthifolius RaddiA. Arnóbio, O. N. Terra Jr., P. R.G. Lemos et al.Phytotherapy consists in all pharmaceutical preparation using certain part of plants as a feedstock with known pharmacological effects for medicinal purposes. In order to a better understanding of the biological effects associated with herbal medicines, many scientific studies have been conducted and developed in recent years. SchinusterebinthifoliusRaddi (Aroeira) is native from Peru and is also found in Europe, Asia and … …American Journal of Infectious Diseases, Vol. 8, Issue 4 · 8 Feb 2013 · 7,616 accessesView PDFCite
Research ArticleOpen accessIn the abstractAntileishmanial and Antibacterial Activity of Essential Oils of Medicinal Plant Achillea santolina L.Abdulkarim Dakah, Mohammed MaarroufAchillea santolina is medicinal plant widely used in folk medicine for gastrointestinal disorders, anti-inflammatory and anti-diuretic. The World Health Organization (WHO) reports that about 350 million people are considered to be at risk of contracting leishmaniasis especially among people living in the developing countries. This research will be the first time that evaluate antileishmanial activity of essential oils of A. … …OnLine Journal of Biological Sciences, Vol. 19, Issue 1 · 2 Mar 2019 · 9,202 accessesView PDFCite