Research ArticleOpen accessIn the abstractDecoupling and Linearizing of a pH Plant using Hirschorn’s and Genetic AlgorithmsJ. Kanakaraj, D. SubbulekshmiProblem statement: This study is to maintain the interacting liquid level and pH parameter at a desired value. The purpose of decoupling and linearization algorithm is to prevent interaction and making the system linear. Approach: In this study Hirchorn’s and Genetic Algorithms (GA) are proposed to make the system linear, non interacting system. This study presents the performance comparison of … …Journal of Computer Science, Vol. 8, Issue 9 · 9 Aug 2012 · 7,190 accessesView PDFCite
Research ArticleOpen accessIn the abstractToxicity of Industrial Wastewater Acting Singly or in Joint-Ratios on Clarias gariepinusAina Olubukola Adeogun, Azubuike Victor ChukwukaFreshwater ecosystems were the most vulnerable to pollution due to their easy accessibility for disposal of wastewaters leading to deterioration of water quality. Ona river, Ibadan, Nigeria is part of a dense network of inland watercourses emptying into the Lagos lagoon and receives industrial effluents from a food and beverage industry. The single and joint-action toxicity of effluents from these … …American Journal of Environmental Sciences, Vol. 8, Issue 4 · 18 Jun 2012 · 7,024 accessesView PDFCite
Research ArticleOpen accessIn the abstractA Bayesian Method for Disentangling Dependent Structure of Epistatic InteractionJing Zhang, Qu Zhang, Darrin Lewis, Michael Q. ZhangProblem statement: We propose a Bayesian method (RBP) to recursively infer the independence structure of epistatic interactions in case-control study. Approach: Based on the results of BEAM2, RBP can powerfully detect the marginal and conditional independence within interacting SNPs even in the complicated interaction cases. Results: We did extensive simulations to test RBP and compare it with stepwise logistic regression. … …Current Research in Biostatistics, Vol. 2, Issue 1 · 13 Jan 2012 · 7,476 accessesView PDFCite
EditorialOpen accessIn the abstractBig Data and Parkinson’s Disease - from Understanding of Disease to Personalised MedicineYen F. Tai, Nicola PaveseThe advancement of information technology in recent years has generated a huge amount of datasets in all areas of scientific research. This has led to new opportunities to harness the 'Big Data' to improve our understanding of diseases - from investigating disease mechanisms to monitoring treatment responses. The Big Data approach is a data-driven and often hypothesis-free, way of studying … …Neuroscience International, Vol. 7, Issue 1 · 27 Jul 2016 · 7,755 accessesView PDFCite
Research ArticleOpen accessIn the abstractQuantification of Zolpidem in Canine PlasmaMario Giorgi, Alessandra Gavazza, Hyoin YunProblem statement: Zolpidem is a non-benzodiazepine hypnotic agent currently used in human medicine. In contrast to benzodiazepines, zolpidem preferentially binds with the GABAA complex ϖ1 receptors while poorly interacting with the other ϖ receptor complexes. Recent studies have suggested that ZP may be used to initiate sedation and diminish severe anxiety responses in dogs. The aim of the present study … …American Journal of Animal and Veterinary Sciences, Vol. 7, Issue 1 · 19 Mar 2012 · 7,908 accessesView PDFCite