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42 results for “Influenza”
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Research ArticleOpen accessEvery word in the titleSearching of Main Cause Leading to Severe Influenza A Virus Mutations and Consequently to Influenza Pandemics/EpidemicsGuang Wu, Shaomin YanThe unpredictable mutations in the proteins from influenza A virus lead to the great difficulty in prevention of possible outbreak of bird flu and pandemic/epidemic of influenza. This unpredictability is due to the fact that we know little about the causes that lead to the mutations. In three of our recent studies on the hemagglutinins from influenza A virus, we … …American Journal of Infectious Diseases, Vol. 1, Issue 2 · 30 Jun 2005 · 9,970 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleOccurrence of Avian Influenza H5N1 among Chicken, Duck Farms and Human in EgyptMohamed S. Diab, Mohamed S. Abd El Hafez, Mohamed A. Ashry, Wael K. ElfeilAvian influenza (AI) H5N1 virus consider a potential threat to the poultry industry with sever zoonotic effect associated with a high risk on human being associated with the poultry production. The disease become endemic in Egypt and cause more than 359 confirmed human infection cases in the last few years. Samples (serum and tissues) collected from 160 poultry farms that … …American Journal of Animal and Veterinary Sciences, Vol. 14, Issue 1 · 22 Feb 2019 · 7,643 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleDocking and Molecular Dynamics Simulations in Potential Drugs Discovery: An Application to Influenza Virus M2 ProteinMarine E. Bozdaganyan, Philipp S. Orekhov, Nicola L. Bragazzi et al.Molecular docking is a common method for searching new potential drugs. Improvement of the results of docking can be achieved by different ways-one of them is molecular dynamics simulations of protein-ligand complexes. As a model for our research we chose M2 membrane protein from influenza virus. M2 protein is a high selective tetrameric pH-gated proton channel. It was previously shown … …American Journal of Biochemistry and Biotechnology, Vol. 10, Issue 3 · 11 Nov 2014 · 8,669 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleInduction of a Soluble Anti-HIV-1 factor (s) with IFN-γ, IL-10, and β-Chemokine Modulating Activity by an Influenza-Bacterial Polyantigenic MixtureJosé W. Rodríguez, Nat O. Pagan, Mar C. Ocasio et al.Partial immune restoration may be obtained with highly active antiretroviral therapy (HAART), but specific anti-HIV-1 immune responses do not appear to improve substantially. We have demonstrated that a soluble factor(s) induced by a mixture of inactivated influenza and bacterial vaccines called polyantigenic immunomodulator (PAI), possesses strong immunoregulatory and anti- HIV-1 activities. In the present study, we show that culture fluids … …American Journal of Infectious Diseases, Vol. 3, Issue 4 · 31 Dec 2007 · 6,845 accessesView PDFCite
Research ArticleOpen accessIn the keywordsDesigning of Disulfide Cyclic Peptide for Inhibiting Polymerase A and B1 (PAC-PB1N) in H1N1 Virus using Molecular Simulation ApproachUsman Sumo Friend Tambunan, Mochammad Arfin Fardiansyah Nasution, Arli Aditya Parikesit et al.The drug resistance A/H1N1 flu virus is emerging rapidly. Therefore, looking for potential therapy is very important. PB2, PB and PA are subunits of viral RNA-dependent RNA polymerase (RdRp). They play an important role in viral replication. The PA and PB1 binding sites can be considered as potential targets for the development of new influenza drugs. The peptide inhibitors can … …OnLine Journal of Biological Sciences, Vol. 16, Issue 3 · 24 Aug 2016 · 7,310 accessesView PDFCite
Research ArticleOpen accessIn the keywordsWhat these Trends Suggest?Shaomin Yan, Guang WuProblem statement: Global warming is one of most significant factors affecting the biological evolution and the influenza is the disease that threatens humans with possible epidemics or pandemics. It would be important to understand if the global warming would have potential impact on the evolution of influenza virus. For this aim, the first would be to study the trend of … …American Journal of Applied Sciences, Vol. 6, Issue 6 · 30 Jun 2009 · 6,883 accessesView PDFCite
Research ArticleOpen accessIn the keywordsThe Role of Neurodevelopmental Genes in Infectious Etiology of AutismS. Hossein FatemiAutism is a neurodevelopmental disorder with both genetic and environmental etiologies. Prenatal infections may play a role in evolution of autism. Experimental evidence shows human influenza viral infection in pregnancy leads to significant deleterious effects in brain structure and function in the developing mouse progeny. Several brain genes of interest in this animal model are also involved in the pathology … …American Journal of Biochemistry and Biotechnology, Vol. 4, Issue 2 · 30 Jun 2008 · 6,563 accessesView PDFCite
Short CommunicationsOpen accessIn the keywordsMolecular Testing for Respiratory Tract Infections May Have Favorable Impact on Real-world Healthcare CostsAzia Evans, Vijay Singh, Pallavi Upadhyay et al.Molecular testing by Polymerase Chain Reaction (PCR) has improved diagnostic performance to inform appropriate treatment. However, its impact on healthcare utilization and costs related to respiratory tract infections are yet to be studied in detail. The aim of this study is to evaluate the costs of healthcare utilization following traditional culture and molecular PCR diagnostic testing for respiratory tract infections. … …American Journal of Infectious Diseases, Vol. 20, Issue 3 · 15 Jan 2025 · 5,262 accessesView PDFCite
Research ArticleOpen accessIn the abstractDeep Learning Synergy: CNNs and Transformers for Epidemic Outbreak ForecastingAlexander R., Shakthi Priya V., Sumathi G. et al.An Accurate prediction of outbreaks is extremely crucial for taking proactive public health interventions, distributing limited resources, and controlling a disease. This paper assesses and also compares the performances of the available deep learning models, namely, Convolutional Neural Network (CNN), Long Short-Term Memory (LSTM) networks, and Bidirectional Long Short-Term Memory (BiLSTM) networks, in predicting. CNNs are best for feature extraction … …Journal of Computer Science, Vol. 21, Issue 12 · 23 Jan 2026 · 2,113 accessesView PDFCite
Research ArticleOpen accessIn the abstractInflammatory Effects of Co-Exposure to Heavy Metals (Cd and Pb) and Respiratory Viruses (229E, OC43, and H3N2) on IL-6 and IL-8 Responses in U87 Glioblastoma CellsHyeokjun Yun, Qian-Wen Wang, Jae Kyung KimCo-exposure to heavy metals and viruses can pose threats to cellular health by increasing cytotoxicity and inflammatory cytokine expression. We aimed to elucidate the interactions between these factors inhuman glioblastoma cells (U87). U87 cells were exposed to influenza A virus (H3N2), coronaviruses OC43 and 229E, and heavy metals Cd and Pb. Cell viability and cytotoxicity were assessed through WST-8 and … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 2 · 5 Jul 2025 · 5,505 accessesView PDFCite