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27 articles for “Inflammatory Conditions”
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Research ArticleOpen accessIn the abstractAnalgesic and Anti-inflammatory Activity of Euphorbia antiquorum LinnBanibrata Das, Samina Alam, Rajib Bhattacharjee, Biplab Kumar DasEuphorbia antiquorum (L.) is used as traditional medicine for various ailments in Bangladesh. But the scientific basis for its use especially in pain and inflammation remains largely unknown. Therefore, the present study was designed to evaluate analgesic and anti-inflammatory effect of the aqueous ethanolic extract of the whole plant. The analgesic activity was evaluated by hot plate, acetic acid induced … …American Journal of Pharmacology and Toxicology, Vol. 10, Issue 2 · 27 Aug 2015 · 9,211 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffects of Unilateral Cervical Vagotomy on Murine Dendritic CellsDaniel Sanzio Gimenes da Cruz, Ana Paula Nascimento de Lima, Patrícia Benites Gonçalves da Silva et al.The cholinergic anti-inflammatory pathway has been demonstrated to be an important mechanism that modulates several inflammatory diseases. This modulation occurs upon activation of the vagus nerve, which modulates splenic macrophages and lymphocytes through the predominant neurotransmitter, Acetylcholine (ACh). We hypothesized that this modulation could also take place in dendritic cells, as these cells represent a link between the innate and … …American Journal of Immunology, Vol. 11, Issue 2 · 12 Jul 2015 · 6,948 accessesView PDFCite
Review ArticleOpen accessIn the abstractNon-Steroidal Anti-Inflammatory Drugs in Food Producing AnimalsDe Vito VirginiaProviding adequate food supply to meet the demands of a growing population is a challenge for this century. The food producing animals bred in optimized conditions supply a large amount of food derivatives. At the same time, society has become progressively more concerned about animal suffering and aware of the need of pain prevention and treatments. One of the measures … …American Journal of Animal and Veterinary Sciences, Vol. 10, Issue 2 · 12 Jun 2015 · 7,715 accessesView PDFCite
Research ArticleOpen accessIn the abstractAnti-Inflammatory, Analgesic and Antioxidant Activities of Allophylus Cobbe LeavesPreeti Jain, Md. Selim Hossain, Kaniz Fatema et al.Allophylus cobbe L. Raeuschel (Family-Sapindaceae) is a medicinal plant used traditionally for the treatment of various health risks like pain, inflammation, ulcers and wounds in Bangladesh. This study determined the polyphenolic compounds and evaluated the analgesic, anti-inflammatory and antioxidant effects of the ethanol extract of Allophylus cobbe leaves. High Performance Liquid Chromatography (HPLC) analysis was used to determine the polyphenolic … …American Journal of Pharmacology and Toxicology, Vol. 9, Issue 4 · 27 Jan 2015 · 8,152 accessesView PDFCite
Research ArticleOpen accessIn the abstractA Brief Overview of the Coxib Drugs in the Veterinary FieldTae-Won Kim, Mario GiorgiTraditional Non-steroidal Anti-Inflammatory Drugs (NAIDs) have been widely used to deal with many inflammatory conditions in veterinary medicine. Nowadays however, as the quality of life of animals is improved, new drug options need to be explored. In this review, the authors report on recent trends and the application of the active ingredients labeled for veterinary purposes. …American Journal of Animal and Veterinary Sciences, Vol. 8, Issue 2 · 5 Jul 2013 · 13,852 accessesView PDFCite
Research ArticleOpen accessIn the abstractButyrate-Mediated Genomic Changes Involved in Non-Specific Host Defenses, Matrix Remodeling and the Immune Response in the Rumen Epithelium of Cows Afflicted with Subacute Ruminal AcidosisLouis Dionissopoulos, Anne Hermen Laarman, Ousama AlZahal et al.Subacute Ruminal Acidosis (SARA) is a disorder in cattle which can lead to chronic inflammation in the rumen epithelium, known as rumenitis. Butyrate has been shown to attenuate some of the detrimental effects of inflammatory gastroenteral disorders but the molecular mechanisms mediated by butyrate have not been defined. The objective of this study was to define the inflammatory-related genomic changes … …American Journal of Animal and Veterinary Sciences, Vol. 8, Issue 1 · 10 Jan 2013 · 8,059 accessesView PDFCite
Research ArticleOpen accessIn the abstractDetection of IL-17 and IL-23 in Plasma Samples of Children with AutismAmanda Enstrom, Charity Onore, Irva Hertz-Picciotto et al.Interleukin-23 (IL-23) is a survival factor for a newly described population of T lymphocytes, namely Th-17 cells, that secrete IL-17, tumor necrosis factor- alpha (TNFα) and IL-6. It has been shown that Th-17 cells are a pathogenic T cell subset involved in autoimmune and chronic inflammatory diseases. Based on the increasing evidence of immune dysfunction in autism, including possible autoimmune … …American Journal of Biochemistry and Biotechnology, Vol. 4, Issue 2 · 30 Jun 2008 · 8,223 accessesView PDFCite
Research ArticleOpen accessIn the abstractCPI-1189 Protects against TNBS-induced Colitis in a Rodent ModelBeverley Greenwood-Van Meerveld, Karl TylerNitrone-related therapeutics (NRTs) represents a new class of molecules that may be effective in treating inflammatory conditions. The goal of this study was to examine the effect of CPI-1189 in a rat model of inflammatory bowel disease (IBD). Colonic inflammation was induced by an enema of trinitrobenzene sulfonic acid (TNBS). Saline-enema treated rats served as controls. After 3 days colonic … …American Journal of Pharmacology and Toxicology, Vol. 2, Issue 2 · 30 Jun 2007 · 7,168 accessesView PDFCite
Research ArticleOpen accessIn the abstractIn vitro Activation of Human and Rat Lymphocyte and Macrophage Functions by NorepinephrineRicardo Gomez-Flores, Diana Caballero-Hernandez, Richard J. Weber et al.Norepinephrine (NE) has been associated not only with increasing blood pressure, atherosclerosis, heart disease, and other life threatening conditions, but also with altering immune responses by influencing leukocyte functions. In the present study, we evaluated the in vitro effects of NE on rat thymic lymphocyte and human peripheral blood mononuclear cells (HPBMC) functions. We observed that NE marginally, but significantly … …American Journal of Immunology, Vol. 1, Issue 4 · 31 Dec 2005 · 7,075 accessesView PDFCite
Research ArticleOpen accessIn the abstractIn vitro Effects of Beet Root Juice on Stimulated and Unstimulated Peripheral Blood Mononuclear CellsChristiana Winkler, Barbara Wirleitner, Katharina Schroecksnadel et al.Intake of fruits and vegetables rich in antioxidants is suggested to reduce the incidence of cancer and coronary heart disease in humans. Exceptional antioxidant activity of beet root extracts has been reported. Likewise in animal models, e.g., extracts of red beetroot Beta vulgaris var. rubra revealed significant tumor inhibitory effects. Red beetroot concentrate is universally permitted as a food ingredient. … …American Journal of Biochemistry and Biotechnology, Vol. 1, Issue 4 · 31 Dec 2005 · 9,522 accessesView PDFCite