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97 articles for “Immunity”
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Research ArticleOpen accessEvery word in the titleInnate, Adaptive and Intrinsic Immunity in Human Immunodeficiency Virus InfectionSuneth S. Perera, Nitin K. SaksenaThe first line of defence of the innate immune system functions by recognizing highly conserved sets of molecular structures specific to the microbes, termed pathogen-associated molecular patterns, or PAMPs via the germ line-encoded receptors Pattern-Recognition Receptors (PRRs). In addition to the innate immune system, the vertebrates have also evolved a second line of defence termed adaptive immune system, which uses … …American Journal of Infectious Diseases, Vol. 8, Issue 3 · 27 Nov 2012 · 9,723 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleThe Innate Immunity in Bovine Mastitis: The Role of Pattern-Recognition ReceptorsFernando Nogueira de Souza, Eduardo Milton Ramos Sanchez, Marcos Bryan Heinemann et al.Mastitis is the most costly disease for dairy farmers and industry, which are mainly caused by the entry of bacteria to the teat canal. Shortly after the entry of the invading bacteria, the innate immunity recognizes the invading pathogen through pattern recognition receptors and initiates the inflammatory response necessary to eliminate the invading bacteria. This initial inflammatory response releases cytokines … …American Journal of Immunology, Vol. 8, Issue 4 · 18 Oct 2012 · 10,352 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleImmunity to Pneumococcal Vaccine in Splenectomized β-Thalassemia PatientsAbdolreza Sotoodeh Jahromi, Mohammad Reza Farjam, Alireza Makarem et al.Problem statement: Splenectomy is accompanied by a lifelong risk of overwhelming post splenectomy infection, mainly caused by encapsulated bacteria such as Streptococcus pneumoniae. The mortality rate in those infected patients remains high. Therefore the pneumococcal polysaccharide vaccine has been recommended. Approach: To obtain information on the immunity levels of pneumococcal antibody, in splenectomized β-thalassemia patients in south of Iran. Patients … …American Journal of Immunology, Vol. 8, Issue 2 · 25 May 2012 · 7,403 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleImmunity to Diphtheria in Haemodialysis PatientsAbdolreza Sotoodeh Jahromi, Mortaza Pourahmd, Sara Azhdari et al.Problem statement: The incidence of infectious diseases is increased in patients with chronic renal failure. Chronic renal failure severely influences the immune functions of the host. Diphtheria is of great epidemiological concern. Although mainly observed during childhood, unvaccinated adults and relatively immunocompromised patients are at increased risk for acquiring diphtheria. Approach: To evaluate the anti-Diphtheria immunity level in southern Iranian … …American Journal of Infectious Diseases, Vol. 7, Issue 1 · 27 Jun 2011 · 8,091 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleBetter Understanding of the Immunosuppressive Link between the Lymphocytic Immune Cells and the Decreased Cell Mediated Immunity in Head and Neck Cancer PatientsA.S. Abdulamir, R.R. Hafidh, N. Abdulmuhaimen et al.The purpose of this study was to determine the phenotyping of Peripheral Blood Lymphocytes (PBL) in Head and Neck Cancers (HNCA) patients and to relate this with the level of Cell-Mediated Immunity (CMI) measured by in vitro lymphoproliferative assay, in order to evaluate immune suppression in HNCA patients and its possible mechanisms. Accordingly, one hundred twenty two HNCA patients and … …American Journal of Immunology, Vol. 4, Issue 3 · 30 Sep 2008 · 7,303 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleAssociation Between Circulating Early Endothelial Progenitors and CD4+CD25+ Regulatory T Cells: A Possible Cross-talk between Immunity and Angiogenesis?Shmuel Schwartzenberg, Adi Mor, Galia Luboshits et al.Regulatory T-cells (Treg) are a recently defined subset of CD4+ cells that can suppress inflammation and induce tolerance. Phenotypically, T-regs are characterized by a high level of expression of the IL-2 receptor alpha chain, CD25. Endothelial progenitor cells (EPCs) can transform into mature endothelial cells and promote vessel formation by inducing postnatal angiogenesis and vasculogenesis. Herein, we tested the hypothesis … …American Journal of Immunology, Vol. 1, Issue 4 · 31 Dec 2005 · 6,902 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleEnhanced Immunity of Hybrid Grouper (Epinephelus sp.) Against Viral Nervous Necrosis Using a Recombinant Protein Nanovaccine from Chlorella VulgarisUun Yanuhar, Herly Evanuarini, Heru Suryanto et al.Hybrid Grouper (Epinephelus sp.) is an important export commodity in marine aquaculture, yet Viral Nervous Necrosis (VNN) remains a major threat. Nanovaccines are a type of vaccine developed by combining vaccine ingredients with silver nanoparticles and recombinant protein from Chlorella vulgaris. These formulations are designed to effectively boost the body's immune system response to prevent disease infection and destroy pathogenic … …OnLine Journal of Biological Sciences, Vol. 25, Issue 3 · 22 Nov 2025 · 2,154 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleASSOCIATION OF TESTOSTERONE AND CHOLESTEROL LEVEL IN MODULATION OF IMMUNITY AND SEVERITY OF DISEASE IN VISCERAL LEISHMANIASIS PATIENTS-A PRELIMINARY STUDYKrishna Pandey, Dharmendra Singh, Sanjiva Bimal et al.Males are more prone to Visceral Leishmaniasis (VL) as compared to females. The role of androgens in host defence against Leishmania and other pathogens is of considerable interest. This study was aimed to understand a baseline mechanistic understanding of the pathogenesis of visceral leishmaniasis with respect to testosterone. We examined the relationship between serum testosterone and cholesterol levels, antigen induced … …American Journal of Immunology, Vol. 10, Issue 1 · 25 Mar 2014 · 7,073 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleCytomegalovirus Immunity in Pregnancy in South of IranAbdolreza Sotoodeh Jahromi, Mahin Jamshidi Makiani, Mohammad Reza Farjam et al.Problem statement: Fetal loss and abortion are responsible for significant emotional distress for couples desiring children. There are many documents which support the role of some certain asymptomatic infections such as Cytomegalovirus (CMV) in spontaneous abortion. This study was aimed to evaluate the prevalence of seropositivity for CMV IgG and IgM in women with abortion and compare it with normal … …American Journal of Infectious Diseases, Vol. 6, Issue 1 · 31 Mar 2010 · 8,145 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleFoxp3-Mediated Immunity of Human Pancreatic Cancer Cell Line PANC-1Renxi Wang, Gencheng Han, Jianan Wang et al.Problem statement: More and more evidences have shown that human cancer cells can express Foxp3, the regulatory T cell-associated transcription factor. The role of Foxp3 in human cancer cells is still unclear. We detected Foxp3 expression in human pancreatic cancer cell line PANC-1. SiRNA assays showed that Foxp3 expression suppressed the expression of TGF-β and IL-10 which could induce immune … …American Journal of Immunology, Vol. 5, Issue 4 · 11 Jan 2010 · 7,363 accessesView PDFCite