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20 articles for “ICH”

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Research ArticleOpen accessIn the author namesA STOCHASTIC FRONTIER APPROACH FOR MEASURING TECHNICAL EFFICIENCY OF SMALL-SCALE IMPROVED SALT PRODUCTION IN GUINEABoubacar Siddighi Balde, Hajime Kobayashi, Makoto Nohmi et al.Salt production is a major driving force behind the loss of mangrove in Guinea. As the traditional salt production causes increasing deforestation, the intensive exploitation of mangrove resources has now reached a critical threshold. Therefore, improved techniques using sunlight as the source of energy has been introduced as an alternative to the traditional salt production techniques which consumes a significant … …American Journal of Applied Sciences, Vol. 11, Issue 8 · 14 May 2014 · 7,641 accessesView PDFCite
Research ArticleOpen accessIn the author namesSCANNING ELECTRON MICROSCOPE IMAGING OF AMYLOID FIBRILSEisuke Takai, Gai Ohashi, Ryuichi Ueki et al.This study demonstrated the applicability of Scanning Electron Microscopy (SEM) for the observation of amyloid fibrils without staining. As model specimens, two types of amyloid fibrils with different shapes and chemical compositions were controllably synthesized from hen lysozyme. The apparent fibril widths in the SEM images were considerably larger than the original diameters analyzed by the conventional techniques of Transmission … …American Journal of Biochemistry and Biotechnology, Vol. 10, Issue 1 · 1 Mar 2014 · 10,330 accessesView PDFCite
Research ArticleOpen accessIn the author namesBiomagnification Profiles of Trace Elements through the Food Web of an Integrated Shrimp Mangrove Farm in Ba Ria Vung Tau, South VietnamNguyen Phuc Cam Tu, Nguyen Ngoc Ha, Hiroaki Matsuo et al.Problem statement: Ba Ria Vung Tau (BRVT), a Vietnamese province with one of the fastest growing economies in the country, faces significant environmental challenges, including increased contamination of rivers and estuaries with urban and industrial wastes. Approach: Concentrations of 23 trace elements and stable isotope ratios (δ13C and δ15N) were analyzed in suspended particulate matter, one species of peanut worm, … …American Journal of Environmental Sciences, Vol. 8, Issue 2 · 9 Mar 2012 · 7,802 accessesView PDFCite
Research ArticleOpen accessIn the author namesAntioxidant Activity of Leaves of Calophyllum rubiginosumMuhammad Taher, Nissad Attoumani, Deny Susanti et al.Problem statement: Calophyllum species have been used in traditional medicine for their therapeutic values for many years. This use was explained by several previous studies where antimicrobial, antifungal, anti-HIV and anti-cancer and antioxidant compounds were isolated from several Calophyllum species. Approach: The leaves were extracted with n-hexane (hexane), dichloromethane (DCM) and methanol using soxhlet apparatus. Total phenolic contents of each … …American Journal of Applied Sciences, Vol. 7, Issue 10 · 31 Oct 2010 · 7,623 accessesView PDFCite
Research ArticleOpen accessIn the author namesIn Silico Analysis of Envelope Dengue Virus-2 and Envelope Dengue Virus-3 Protein as the Backbone of Dengue Virus Tetravalent Vaccine by Using Homology Modeling MethodUsman Sumo Friend Tambunan, Arli Aditya Parikesit, Hendra et al.Problem statement: Dengue fever, which was caused by Dengue virus infection, had became a major public health problem in the tropic and subtropical countries. Dengue virus (DENV) had four serotypes (DENV-1, DENV-2, DENV-3 and DENV-4), based on their immunogenic in the human body. Preventive measure will be necessary to decrease the prevalence of dengue fever, by developing modern vaccine. Approach: … …OnLine Journal of Biological Sciences, Vol. 9, Issue 1 · 3 Sep 2010 · 9,265 accessesView PDFCite
Research ArticleOpen accessIn the author namesLoss of Morphine-induced Suppression of NK Cell activity and T-cell Functions in µ-Opioid Receptor Knockout MiceRichard J. Weber, Ricardo Gomez-Flores, Ichiro Sora, George R. UhlIn vivo administration of µ-opioid receptor selective agonists to various species is known to suppress lymphocyte, NK cell, and macrophage functions, in addition to mediate pain relief and euphoria. Using a mouse model in which the µ-opioid receptor gene was disrupted by targeted homologous recombination, we explored the involvement of this receptor in natural killer (NK) cell activity and T … …American Journal of Immunology, Vol. 2, Issue 2 · 30 Jun 2006 · 6,937 accessesView PDFCite
Research ArticleOpen accessIn the abstractGreen Tea Treatment Attenuates Oxidative Damage and Neuromotor Deficit Induced by an Experimental Model of Intracerebral Hemorrhage in RatsMauren Assis Souza, Caroline Dalla Colletta Altermann, Alexandre dos Santos Martins et al.The present study shows the neuroprotective effect of green tea supplementation (GT; Camellia sinensis) in a model of Intracerebral Hemorrhage (ICH) in rats. ICH was induced by intra-striatum collagenase infusion in male Wistar rats. GT (400 mg Kg-1) was administered via gavage for 10 days after ICH. We assessed the effect of GT on neuromotor recovery and oxidative damage. Our … …Neuroscience International, Vol. 7, Issue 2 · 19 Mar 2017 · 8,598 accessesView PDFCite
Research ArticleOpen accessIn the abstractAetiology of Spontaneous Intracerebral Haemorrhage in Young Adults Admitted at a Tertiary Care Hospital in DhakaMohammad Enayet Hussain, Quazi Deen Mohammad, Monsur Habib et al.Spontaneous Intracerebral Haemorrhage (SICH) in young adult occurs due to multiple risk factors. The purpose of the present study was to determine the aetiological factors of spontaneous intracerebral haemorrhage in the young adult patients. This case control study was carried out in the Department of Neurology, Department of Neurosurgery and Department of Internal Medicine at Dhaka Medical College Hospital, Dhaka … …Neuroscience International, Vol. 6, Issue 2 · 2 Oct 2015 · 7,051 accessesView PDFCite
Review ArticleOpen accessIn the abstractSelected Genotoxic Impurities Profiling During WFI Qualification to Control Carcinogenesis in Large Volume ParenteralsMohabbat UllahWater For Injections (WFI) which is the main vehicle of Large Volume Parenterals (LVPs) should be free from trace amount of genotoxic impurities. This review gives emphasis on quantification of genotoxic trace metals during qualification of WFI in LVPs manufacturing unit. According to ICH guidelines, impurities related to drug substances are classified into three main categories: Organic impurities, inorganic (elemental) … …American Journal of Pharmacology and Toxicology, Vol. 10, Issue 1 · 27 May 2015 · 7,708 accessesView PDFCite
Research ArticleOpen accessIn the abstractINVESTIGATION OF STABILITY OF KOREAN GINSENG IN HERBAL DRUG PRODUCTLatifa Bashir Babiker, Elrasheed Ahmed Gadkariem, Riyadh Mohammed Alashban, Haya Ibrahim ALjoharThis study was designed to investigate long term stability of K-Gin capsules, a herbal medication that contains korean ginseng. Stability studies ensuring the maintenance of product quality, safety and efficacy throughout the shelf life are considered as pre-requisite for the acceptance and approval of any pharmaceutical product. Conducting long term stability studies following the guidelines issued by ICH, WHO and … …American Journal of Applied Sciences, Vol. 11, Issue 1 · 18 Dec 2013 · 9,221 accessesView PDFCite