Research ArticleOpen accessIn the abstractActin Cytoskeleton and Related Proteins Role During Immune Cells Migration, Polarity and Activation: An OverviewClaudio Vieira da SilvaImmune cells migration, polarity and activation are essential during host immune response. Upon recognition of specific peptides presented by Human Leukocyte Antigen (HLA) molecules on Antigen Presenting Cells (APC), lymphocytes execute subset-related functions such as killing, help and regulation. These cells travel through the organism in a succession of steps, including entry into tissues, interstitial migration, APC scanning, synapse formation … …American Journal of Immunology, Vol. 9, Issue 4 · 19 Nov 2013 · 6,783 accessesView PDFCite
Research ArticleOpen accessIn the abstractNevirapine Hepatotoxicity: Implications of Risk FactorsElias Adikwu, Oputiri Deo, Oru-Bo Precious Geoffrey, D. Akuegbe EnimeyaHighly active antiretroviral therapy is used in the management of HIV/AIDS; it has contributed tremendously in the reduction of mortality and morbidity rate in HIV patients. Despite the outstanding achievement with the use of HAART its major limitation is toxicity. Among these toxicities is hepatotoxicity which is said to be associated with nevirapine containing highly active antiretroviral therapy. Recent reports … …American Journal of Pharmacology and Toxicology, Vol. 8, Issue 2 · 3 Jun 2013 · 7,655 accessesView PDFCite
Research ArticleOpen accessIn the abstractRal-Binding Protein is Required for the Maturation and Function of Dendritic CellsJozef Borvak, Mukesh Sahu, Varun Joy et al.Problem statement: Dendritic Cells (DCs) integrate responses of innate and adaptive immune system via transmitting pro-inflammatory and regulatory signals to naïve cells within draining lymph nodes. DCs have high capacity for endocytosis, both Clathrin-Dependent (CDE) and Caveolin-Dependent (CvDE). Approach: We have recently shown that ATP-hydrolysis by the multifunctional transporter protein RLIP76 is the primary determinant of the rate of CDE. … …American Journal of Immunology, Vol. 6, Issue 3 · 13 Sep 2010 · 8,098 accessesView PDFCite
Research ArticleOpen accessIn the abstractA CNN-KNN Based Recognition of Online Handwritten Symbols within Physics Expressions Using Contour-Based Bounding Box (CBBS) Segmentation TechniqueUjwala Kolte, Sachin Naik, Vidya KumbharArtieres, T., Marukatat, S., & Gallinari, P. (2007). Online Handwritten Shape Recognition Using Segmental Hidden Markov Models. IEEE Transactions on Pattern Analysis and Machine Intelligence, 29(2), 205–217. https://doi.org/10.1109/tpami.2007.38 Baró, A., Riba, P., Calvo-Zaragoza, J., & Fornés, A. (2019). From Optical Music Recognition to Handwritten Music Recognition: A baseline. Pattern Recognition Letters, 123, 1–8. https://doi.org/10.1016/j.patrec.2019.02.029 Bresler, M., Prua, D., & Hlavác, … …Journal of Computer Science, Vol. 20, Issue 7 · 7 May 2024 · 6,282 accessesView PDFCite