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155 articles for “HIV”
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Research ArticleOpen accessEvery word in the titleAntibody Responses to HIV-1 gp120 Hypervariable Regions in Six Long-Term Non-ProgressorsRebecca Rivera, Kyung Hee Kang, Murray B. Gardner et al.Our long-term goal is to discover the combination of host parameters that help some HIV-infected individuals to resist progression to AIDS. In this study, we examined antibody responses using multiple samples obtained from a cohort of Long-Term Non-Progressors (LTNPs). Our hypothesis is that antibody responses to variable regions of the HIV-1 envelope glycoprotein are involved in reducing the viral load … …American Journal of Infectious Diseases, Vol. 12, Issue 2 · 1 Jul 2016 · 7,649 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleA New Proposed Statistically-Derived Compromise Cut-off CD4 Count Value for HIV Patients to Start using ARVsMaria Mokgadi Lekganyane, Solly Matshonisa SeeletseThe study investigated the relationship between statistical outliers and the inconsistent values of the CD4 count recommended for starting the Antiretroviral Therapy (ART) by HIV-positive patients. Low CD4 counts imply a low immune system. It could be due to AIDS existence or closeness to death. An effective treatment to curb HIV impact is ART, which is recommended for low CD4 … …American Journal of Applied Sciences, Vol. 13, Issue 7 · 29 Jun 2016 · 7,333 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleDetermination of Predictors Associated With HIV/AIDS Patients on ART Using Accelerated Failure Time Model for Interval Censored Survival DataPrafulla Kumar Swain, Gurprit GroverThe main objective of this paper is to identify the independent predictors affecting the survival of HIV/AIDS infected patients on Antiretroviral Therapy (ART), an interval censored event time outcome. A total of 2052 HIV/AIDS patients, who were on ART at Ram ManoharLohia Hospital, New Delhi, India, during the period of April 2004 to December 2010, were included for analysis. Accelerated … …Current Research in Biostatistics, Vol. 6, Issue 1 · 12 Jan 2016 · 8,311 accessesView PDFCite
Research ArticleOpen accessEvery word in the titlePREVALENCE OF AUTOANTIBODIES REVEALS A PREDOMINANT SMA AND ANCA-PR3/MPO PATTERN IN HIV INFECTION AND SMA IN HAV-INFECTED CHILDRENLuz M. Navarta, Carlos A. Espul, Nelson Acosta-RiveroHepatitis A Virus (HAV) and Human Immunodeficiency Virus (HIV) have been associated with development of autoantibodies and autoimmune manifestations in children. Autoimmune Hepatitis (AIH) is particularly aggressive in children/adolescents with a more severe outcome. Thus, studying the mechanisms of virus-related autoimmune disorders in children is a relevant topic of research. We aimed to study the prevalence of autoantibodies in plasma … …American Journal of Immunology, Vol. 10, Issue 3 · 18 Sep 2014 · 7,038 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleMULTI-STATE MODELS OF HIV/AIDS BY HOMOGENEOUS SEMI-MARKOV PROCESSZelalem Getahun DessieMulti-state stochastic models are useful tools for studying complex dynamics such as chronic diseases. The purpose of this study is to determine factors associated with the progression between different stages of the disease and to model the progression of HIV/AIDS disease of an individual patient under ART follow-up using semi-Markov processes. A sample of 1456 patients has been taken from … …Current Research in Biostatistics, Vol. 4, Issue 2 · 11 Aug 2014 · 8,209 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleAnamnestic Immune Response Eight Years After Immunization of Primates with a Multivalent HIV-1 GP120 Variable Peptide VaccineRebecca Rivera, Kyung Hee Kang, David E. Anderson et al.Successful development of an effective HIV vaccine hasn’t occurred yet partly as a consequence of the antigenic variation deployed by HIV-1 to escape the immune system. Our laboratory is dedicated to develop a single peptide synthesis approach to create multivalent peptides representing hypervariable epitopes of the gp120 envelope glycoprotein of HIV-1. Our previous study showed that our HIV HECs are … …American Journal of Immunology, Vol. 9, Issue 1 · 13 Mar 2013 · 7,209 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleNutritional Status and Quality of Life of Women with HIV/AIDSAnanya Bhowmik, Padmini Ghugre, Shobha Udipi, Subhasish Kamal GuhaProblem statement: HIV infection is a multisystem disorder which causes chronic infections that lead to profound immune- suppression. Women have always been a vulnerable section of the society. They are doubly vulnerable due to the HIV and malnutrition vicious cycle, which may affect their Quality Of Life (QOL). There are different literature reviews which suggest under-nutrition, wasting due to HIV … …American Journal of Infectious Diseases, Vol. 8, Issue 1 · 22 Feb 2012 · 8,282 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleDetection of Extended-Spectrum β Lactamases and AmpC β-Lactamase Production in Escherichia coli Causing Urinary Tract Infection among HIV and Non-HIV PatientsPadmavathy Kesavaram, Padma Krishnan, Rajasekaran SikhamaniProblem statement: Opportunistic infections have been documented as a leading cause of morbidity among HIV patients. Gram negative pathogens that elaborate beta-lactamases have been reported to be associated with increased morbidity and mortality, especially amongst immunocompromised patients on intensive care and high-dependency units. The most common mechanism of β-lactam drug resistance in Escherichia coli include ESBL, AmpC production. Approach: In … …Current Research in Medicine, Vol. 2, Issue 1 · 18 Aug 2011 · 7,834 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleEvaluation of Nested PCRs targeting the BI and SAG2 Genes For Detection of Toxoplasma gondii Genome in Aqueous Humor From HIV Positive Toxoplasma Retinochoroiditis Patients in a Tertiary Eye HospitalB. Mahalakshmi, K.L. Therese, R. Kirthika et al.Abstract: Problem statement: To evaluate nPCR targeting B1 gene (primer set 1) with 3 other nPCRs targeting B1 gene (primer set 2), 3' end of SAG2 and 5' end of SAG2 gene, for detection of Toxoplasma gondii (T. gondii) genome on AH from HIV positive TRC patients. Approach: DNA extracted from AH of 12 TRC patients and 12 controls (patients … …Current Research in Medicine, Vol. 1, Issue 2 · 31 Dec 2010 · 6,886 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleKnowledge and Attitude of Persons Living with HIV+/AIDS (PLWAs) Towards HIV/AIDS in IranJamshidi Makiani Mahin, Davoodian Parivash, Abdoul Hossain Madani et al.Problem statement: As number of Persons Living with HIV/AIDS (PLWAs) increases, caring for them is a new rising problem. The World Health Organization encourages caring these people at home. Patients themselves also prefer to stay at home than staying in hospital. Adequate knowledge and positive attitude are important factors in providing better care for a patient. Approach: This study was … …American Journal of Infectious Diseases, Vol. 6, Issue 3 · 30 Sep 2010 · 8,260 accessesView PDFCite