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18 results for “Granuloma”
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Research ArticleOpen accessIn the abstractEndoscopic Changes of Nasal Mucosa in Patients with LeprosyCarla Andrea Avelar Pires, Eline Pinheiro Weba Costa, Marcus Vinicius Duarte Costa et al.Leprosy is a chronic granulomatous disease, affecting the skin and Schwann cells of peripheral nerves. In most leprosy cases, the nasal mucosa is affected. We aimed to describe the clinical changes in nasal mucosa using nasal endoscopy, in patients with leprosy attending a dermatology service in an endemic region and compare this changes with those founds in non-leprosy patients nasal … …American Journal of Infectious Diseases, Vol. 15, Issue 2 · 3 May 2019 · 7,270 accessesView PDFCite
Research ArticleOpen accessIn the abstractClinio-Pathological Changes in Goats Challenged with Corynebacterium Peudotuberculosis and its Exotoxin (PLD)Z. K.H. Mahmood, F. F. Jesse, A. A. Saharee et al.Caseous lymphadenitis (CLA) is a chronic disease caused by Corynebacterium pseudotuberculosis. However, there is a paucity of data about the C. pseudotuberculosis exotoxin, phospholipase D (PLD) response during the course of CLA. Therefore, this study was conducted to observe the clinical signs and the cellular changes after an experimental infection of the C. pseudotuberculosis and phospholipase D challenge. Twenty six … …American Journal of Animal and Veterinary Sciences, Vol. 10, Issue 3 · 26 May 2015 · 8,316 accessesView PDFCite
Research ArticleOpen accessIn the abstractNitric Oxide Donors with Therapeutic Strategic in Experimental Schistossomiasis MansoniWander Rogério Pavanelli, Jean Jerley Nogueira da Silva, Carolina Panis et al.Schistosomiasis, an immune disease, remains a major public health problem in endemic area. To determine the influence of Nitric Oxide (NO) on this disease, we tested two compounds (Trans-[Ru(bpy)2(NO)SO3](PF6)-PF6 and Na2[Fe(CN)5(NO)]-SNP, which releases NO when activated by biological reducing agents, in BALB/c mice infected subcutaneously by Schistosoma BH strains. The parasitic activity of NO-donors was evaluated in this model by … …American Journal of Immunology, Vol. 10, Issue 4 · 24 Feb 2015 · 7,851 accessesView PDFCite
Research ArticleOpen accessIn the abstractA SHORT INTERFERING RNA MOLECULAR BEACON FOR THE ATTENUATION OF MYCOBACTERIAL INFECTIONRemo George, Kathy Nugent, Norman Bolus et al.The ability of the pathogen Mycobacterium Tuberculosis (MTB) to invade and survive within macrophages of granulomas is attributed to the product of the Mammalian Cell Entry (MCE) operon whose gene, mce4A, encodes a cholesterol transporter that transports host lipids into the bacterium that allows the bacterium to survive during chronic infection. Here, we proposed and tested the hypothesis that a … …American Journal of Biochemistry and Biotechnology, Vol. 10, Issue 1 · 4 Mar 2014 · 7,774 accessesView PDFCite
Research ArticleOpen accessIn the abstractUnique Characteristic Features of Mycobacterium Tuberculosis in Relation to Immune SystemRajni, Laxman S. MeenaProblem statement: Tuberculosis is a leading global mortality factor which has not been effectively controlled, with 1.7 million deaths per year and 8.9 million new cases. Aerobic microbe Mycobacterium Tuberculosis H37Rv (MTB) is the causative agent of tuberculosis. Approach: It is unique among prokaryotes due to its exceptional features contributing to its survival within the hostile environment of macrophages. Results: … …American Journal of Immunology, Vol. 7, Issue 1 · 16 Aug 2011 · 17,211 accessesView PDFCite
Research ArticleOpen accessIn the abstractA 30 Year Old Man with Fever and Indolent Soft Tissue MassesWissam Zaeeter, Ashwin Jathavedam, Rosalyn StahlAbstract: Problem statement: Multifocal Skeletal Tuberculosis (MSTB) is a rare presentation of skeletal tuberculosis. The indolent nature of this condition often leads to delayed or missed diagnosis, sometimes with devastating consequences for the patient. In order to provide meaningful clinical information and to highlight pitfalls in diagnosis of MFST, we present a case of MSTB. A review of this condition … …American Journal of Infectious Diseases, Vol. 6, Issue 3 · 30 Sep 2010 · 7,713 accessesView PDFCite
Research ArticleOpen accessIn the abstractAn Unusual Association between Chromoblastomycosis and Jorge Lobo’s Disease in the Same Patient from the Amazon RegionMaurimelia M. da Costa, Silvia H. Marques da Silva, Hugo J. R. Almeida et al.A clinical case of co-infection Cladophialophora sp. and Lacazia loboi is described and in a same patient with an 18-year history of verrucous plaques and parakeloidal nodular lesions. A 50-yearold man, a laborer, living in the Anajás city, Para, Brazil (rural Amazon region), was seen at the Evandro Chagas Institute’s ambulatory. Histopathological analysis revealed intense hyperplasia and hyperkeratosis of the … …American Journal of Agricultural and Biological Sciences, Vol. 3, Issue 3 · 30 Sep 2008 · 7,747 accessesView PDFCite
Research ArticleOpen accessIn the abstractColourimetric Determination of Phospholipase Activities in Balamuthia mandrillarisSyed Razi HaiderBalamuthia mandrillaris is a recently identified protozoan pathogen that can cause fatal granulomatous encephalitis however the pathogenesis and pathophysiology associated with Balamuthia encephalitis remain unclear. We have recently isolated B. mandrillaris from a 33-years old male who died of encephalitis. Using this isolate, we demonstrated for the first time that B. mandrillaris exhibited phospholipase activities. More specifically, B. mandrillaris exhibited … …American Journal of Biochemistry and Biotechnology, Vol. 3, Issue 3 · 30 Sep 2007 · 6,771 accessesView PDFCite