16 articles for “Gene expressions”

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Research ArticleOpen accessIn the abstractAntibiotic Resistance in Co-Culture Biofilm of Listeria monocytogenes J0161Prem Saran Tirumalai, Soam PrakashProblem statement: Do naturally group-living bacteria express genes the same way as they do in lab grown pure cultures? An intriguing question. Listeria monocytogenes, a dreaded pathogen has been and continues to be a subject of study with reference to gene expressions. However, all studies concerning the gene expression of L. monocytogenes have been done on pure culture states. Our … …Current Research in Microbiology, Vol. 3, Issue 1 · 29 Mar 2012 · 10,216 accessesView PDF Cite

Research ArticleOpen accessIn the abstractAn Efficient Unified K-Means Clustering Technique for Microarray Gene Expression DataP. Valarmathie, K. Dinakaran, T. RavichandranProblem statement: Using microarray techniques one could monitor the expressions levels of thousands of genes simultaneously. One challenge was how to derive meaningful insights into expressed data. This might be carried out by clustering techniques such as hierarchical and k-means, but most of the clustering techniques were largely heuristic in nature and are associated with some unresolved issues like how … …Journal of Computer Science, Vol. 7, Issue 7 · 28 Jun 2011 · 6,912 accessesView PDF Cite

Research ArticleOpen accessIn the abstractMethamphetamine Regulation of Sulfotransferases in Rat Liver and BrainTianyan Zhou, Chaoqun Huang, Yue Chen et al.Problem statement: Sulfotransferases (SULTs) are important phase II drug metabolizing enzymes. They also regulate the biological activities of various hormones. To the best of our knowledge, psychostimulants regulation of SULTs is basically not studied except one article reported that Methamphetamine (METH) treatment induced rat amygdale rSULT1A1 mRNA 4.3 fold by using microarray method to identify a series of candidate genes … …American Journal of Pharmacology and Toxicology, Vol. 5, Issue 3 · 30 Sep 2010 · 7,683 accessesView PDF Cite

Research ArticleOpen accessIn the abstractAmelioration of Inducible Nitric Oxide Synthase, Insulin like Growth Factor-1 Gene Expression and Insulin Receptor Substrate-1 in Liver Tissue of Insulin Resistant Rats Treated With L-CarnitineHala M. GhanemProblem statement: It has been reported that genes expression (inducible Nitric Oxide (iNOS). Insulin-like Growth Factor-1(IGF-1) have a role in both glucose homeostasis and insulin resistance. The aim of this study was designed to evaluate the amelioration of the iNOS, IGF-1 genes expression as well as IRS-1 in liver tissues of rats fed high fructose diet treated with Lcarnitine. Approach: … …American Journal of Biochemistry and Biotechnology, Vol. 6, Issue 3 · 30 Sep 2010 · 7,264 accessesView PDF Cite

Research ArticleOpen accessIn the abstractTaxonomically Clustering Organisms Based on the Profiles of Gene Sequences Using PCAE. Ramaraj, M. PunithavalliThe biological implications of bioinformatics can already be seen in various implementations. Biological taxonomy may seem like a simple science in which the biologists merely observe similarities among organisms and construct classifications according to those similarities[1], but it is not so simple. By applying data mining techniques on gene sequence database we can cluster the data to find interesting similarities … …Journal of Computer Science, Vol. 2, Issue 3 · 31 Mar 2006 · 6,746 accessesView PDF Cite

Research ArticleOpen accessIn the abstractA Feasibility Study of Challenges and Opportunities in Computational Biology: A Malaysian PerspectiveR. J.A. Richard, N. SriraamThe term computational biology refers to the knowledge derived from a computer analysis of biological data that includes identification of genes in DNA sequence of different organisms, prediction of structural and functional mechanism of proteins, feature extraction and classification of genomics and proteomics. Computational biology is a rapidly developing branch of science and is highly interdisciplinary, using techniques and Concepts … …American Journal of Applied Sciences, Vol. 2, Issue 9 · 30 Sep 2005 · 6,924 accessesView PDF Cite