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33 results for “GSH-Px”
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Research ArticleOpen accessIn the abstractToxicological Consequences of Di-N-Butyl-Phthalate (DBP) on Health of Nile Tilapia FingerlingsEhsan H. Abu Zeid, Al Shimaa A. KhalilPhthalic Acid Esters (PAEs) are mainly used in the plastics industry as adhesives and plasticizers. Di-n-Butyl Phthalate (DBP) is one of the important members in the family of PAEs was listed as environmental priority pollutants by the US Environmental Protection Agency. The objective of this study was to evaluate the toxicological consequences in Nile Tilapia Oreochromis niloticus L. fingerlings, exposed … …American Journal of Animal and Veterinary Sciences, Vol. 9, Issue 4 · 24 Dec 2014 · 8,466 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Role of Nf-Kappa and HDCA and Implication of Oxidative Stress in Airway Inflammation of Chronic Obstructive Pulmonary DiseaseGhada A. Abdallah, Nevine M. Abd-Elfattah, Hala M. Ghanem et al.Oxidative stress has been implicated in the pathogenesis of Chronic Obstructive Pulmonary Disease (COPD), due to its effect on proinflammatory gene transcription. Oxidants/antioxidants imbalance is responsible for disease development. The study was designed to assess oxidative stress and inflammation in COPD patients. The level of TNF-α and IL-8 in sputum and BAL were compared. NF-κB and HDAC were measured in … …American Journal of Biochemistry and Biotechnology, Vol. 10, Issue 4 · 4 Dec 2014 · 6,836 accessesView PDFCite
EditorialOpen accessIn the abstractGLUTATHIONE: A POSSIBLE LINK TO AUTOPHAGY IN SYSTEMIC LUPUS ERYTHEMATOSUSDilip Shah, Swapan K. NathIncreased free radical formation and altered redox state are of fundamental importance in the pathogenesis of autoimmune diseases including Systemic Lupus Erythematos (SLE). Free radicals are mainly derived from oxygen (Reactive Oxygen Species/ROS) and nitrogen (Reactive Nitrogen Species/RNS) at mitochondria, cellular membranes and the endoplasmic reticulum membrane as physiological responses to a variety of internal and external stress (Shah et … …American Journal of Immunology, Vol. 10, Issue 3 · 3 Sep 2014 · 12,773 accessesView PDFCite
Research ArticleOpen accessIn the abstractPROTECTIVE ROLE OF VITAMIN C AND GREEN TEA EXTRACT ON MALATHION-INDUCED HEPATOTOXICITY AND NEPHROTOXICITY IN RATSRabab R. Elzoghby, Ahlam F. Hamoda, A. Abdel-Fatah, Mona FaroukThe present study was designed to determine the modulating effect of green tea and vitamin C against adverse effects of malathion. Animals were divided into four groups 5 rats /group). Group one was used as a control. Group two given malathion (50 mg/kg/day; 1/50 of the LD50 for four weeks). Group three and Group four were given malathion (50 mg/kg/day; … …American Journal of Pharmacology and Toxicology, Vol. 9, Issue 3 · 22 Jul 2014 · 8,171 accessesView PDFCite
Research ArticleOpen accessIn the abstractIMPACT OF DEHYDROEPIANDROSTERONE IN PREVENTION OF PARACETAMOL INDUCED NEPHROTOXICITY IN RATSAbbas O. ElkaribParacetamol (PCM) overdose can cause nephrotoxicity with oxidative stress as one of the possible mechanisms mediating the event. However, Dehydroepiandrosterone (DHEA), the major secretory product of the human adrenal gland, has been shown to possess a multi-targeted antioxidant activity which is also effective against lipid peroxidation induced in various animal models and against various human disorders. In this study, the … …Current Research in Medicine, Vol. 5, Issue 1 · 26 Mar 2014 · 7,566 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffect of Virgin Olive Oil (Olea europea. L) on Kidney Function Impairment and Oxidative Stress Induced by Mercuric Chloride in RatsYoucef Necib, Ahlem Bahi, Sakina Zerizer et al.The study was designed to investigate the possible protective role of virgin olive oil in mercuric chloride induced renal stress, by using biochemical approaches. The effects of virgin olive oil on mercuric chloride induced oxidative and renal stress were evaluated by serum creatinine, urea and uric acid levels, kidney tissue lipid peroxidation, GSH levels, GSH-Px and GST activities. Administration of … …American Journal of Biochemistry and Biotechnology, Vol. 9, Issue 4 · 20 Dec 2013 · 16,786 accessesView PDFCite
Research ArticleOpen accessIn the abstractToxicity of Zinc Oxide Nanoparticles in Lung Tissue After Repeated Oral AdministrationAtaollah Shokouhian, Saman Soheili, Saeed Moradhaseli et al.Pathological experiments should be considered following oral administration of ZnO. Effect of different doses of ZnO nanoparticle on LDH in oral method showed significant differences in control group (p<0.05) at high dose. Levels of IgG, TNF-α and IL-6 also elevated after administration of ZnO. The level of GSH decreased significantly. Lung damages included hyperemia and bleeding, atelectasis, light emphysema, pribronchiolitis, … …American Journal of Pharmacology and Toxicology, Vol. 8, Issue 4 · 21 Oct 2013 · 7,703 accessesView PDFCite
Research ArticleOpen accessIn the abstractHepatoprotective Effect of N-Acetylcystiene on the Toxic Hazards of titanium Dioxide NanoparticlesHossam Fouad Attia, Mohamed Mohamed Soliman, Gamal Hassan Abdel-Rahman et al.The present study was directed to evaluate the toxic effects of orally administered titanium dioxide naonparticles (TiO2) on liver of male albino rats and to evaluate the ameliorative effects of N-acetylcysteine (NAC). Forty adult male albino rats were divided into 4 groups; control group, NAC group, TiO2 group and TiO2/ NAC group. Rats were administered either TiO2 (1200 mg kg-1 … …American Journal of Pharmacology and Toxicology, Vol. 8, Issue 4 · 26 Sep 2013 · 8,133 accessesView PDFCite
Research ArticleOpen accessIn the abstractEvaluation of Thai Style Stretching Exercise on "Ruesi Dud Ton" on Physical Health and Oxidative Stress in Healthy VolunteerJintanaporn Wattanathorn, Tasanee Boonterm, Wipawee Thukhummee et al.Despite the health benefit reputation of Thai stretching exercise "Ruesi dud ton", no scientific evidence is available. Therefore, we aimed to determine the effect of Thai style stretching exercise on physical health and oxidative stress markers including Malondialdegyde (MDA) level and the activities of main scavenger enzymes including Superoxide Dismutase (SOD), Catalase (CAT) and Glutathione Peroxidase (GSH-Px). We had determined … …OnLine Journal of Biological Sciences, Vol. 12, Issue 4 · 22 Feb 2013 · 7,739 accessesView PDFCite
Research ArticleOpen accessIn the abstractPossible Mechanism of Plumbago zeylanica in Prevention of Hepatic Dammage in Wistar RatRohit Goyal, Pyare Lal SharmaPlumbago zeylanica root has been used traditionally to treat various body ailments including liver diseases. The present study was designed to investigate the hepatoprotective effects of standardized methanolic extract of Plumbago zeylanica root on paracetamol, CCl4 and alcohol induced hepatic injuries in rats and its possible mechanism(s) of hepatoprotection. Administration of hepatotoxicants like paracetamol (3 g kg-1, p.o.) or CCl4 … …American Journal of Pharmacology and Toxicology, Vol. 7, Issue 3 · 20 Nov 2012 · 7,638 accessesView PDFCite