Research ArticleOpen accessIn the abstractEpigenetic Regulation of Extracellular Matrix Remodeling in Skin Aging: Mechanisms and InteractionsJiguang Yang, Yusong Shi, Xiaoqing YanSkin aging results from complex interactions between genetic factors, environmental stressors, and epigenetic modifications that regulate extracellular matrix (ECM) remodeling. Accumulation of senescent cells impairs tissue regeneration through mechanisms including telomere shortening, reactive oxygen species accumulation, and ultraviolet (UV) radiation exposure. While epigenetic pathways regulate skin homeostasis, regeneration, and senescence, the specific epigenetic changes occurring during UV exposure, chronological aging, … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 4 · 15 Feb 2026 · 1,458 accessesView PDFCite
Research ArticleOpen accessIn the abstractEnhancing Facial Expression Recognition Accuracy Through Haar Cascade-Based Feature ExtractionThambusamy Velmurugan, Lakshminarayanan MeenaFacial Expression Recognition (FER) has a significant interest because of its increased applications in Human-Computer Interaction (HCI), like video interactions, emotion analysis, image indexing, and retrieval and many more. In the discipline of computer vision, pattern recognition, and artificial intelligence FER has become an extremely active research topic. A crucial component of FER systems is feature extraction, which involves identifying … …Journal of Computer Science, Vol. 21, Issue 12 · 21 Jan 2026 · 1,656 accessesView PDFCite
Research ArticleOpen accessIn the abstractExpression and Induction Optimization of Mucor Circinelloides Lipase in Escherichia ColiYueping Yang, Yao Zhang et al.Microbial lipases serve as versatile biocatalysts for modifying lipid substrates, enabling diverse biotechnological applications spanning food technology, renewable energy production, and pharmaceutical sectors. Genomic analysis of Mucor circinelloides WJ11 revealed multiple lipase-encoding genes, with WJ_23 successfully cloned and heterologously expressed in Escherichia coli. Since the lipase expression was mainly concentrated in the cell pellets, appropriate induction strategies had been investigated … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 2 · 13 Jun 2025 · 5,982 accessesView PDFCite
Research ArticleOpen accessIn the abstractSeparation, Purification and Anti-aging Activity of Tobacco PolysaccharidesMengyue Huang, Jingwu Song, Shuaishuai Chang et al.To separate tobacco polysaccharides and investigate their antioxidant and anti-aging properties, crude tobacco polysaccharides were extracted from raw tobacco using hot water, followed by purification through DEAE-52 cellulose column chromatography. The molecular weight and monosaccharide composition of the isolated polysaccharides were analyzed using HPGPC and HPLC. The antioxidant activities of these tobacco polysaccharides were tested using DPPH, ABTS, hydroxyl radicals … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 1 · 15 Jan 2025 · 5,103 accessesView PDFCite
Review ArticleOpen accessIn the abstractMachine Learning Integration for Precise Facial Micro-Expression RecognitionViola Bakiasi Shtino, Markela Muça, Senada BushatiThis study advances facial micro-expression recognition through innovative machine-learning techniques, addressing critical needs in psychology, security, and human-computer interaction. The purpose of this study is to improve micro-expression recognition through the optimization of feature transformation and machine learning algorithms. We introduce a novel approach combining Kernel Principal Component Analysis (KPCA) and Uniform Manifold Approximation and Projection (UMAP) for dimensionality reduction, … …Journal of Computer Science, Vol. 20, Issue 11 · 22 Oct 2024 · 5,592 accessesView PDFCite
Research ArticleOpen accessIn the abstractMultimodal Face Expression Recognition Using Parametric Exponential Linear Unit-Long Short-Term MemoryKampa Ratna Babu, Akula Suneetha, Kampa Kanthi KumarMultimodal facial expression recognition combines information from multiple modalities of audio and video to achieve the required accuracy and robustness. By integrating different data sources, multimodal systems capture different aspects of human expression. However, accurately recognizing facial expressions across audio and video modalities causes challenges due to variations in expression representation. In this research, Parametric Exponential Linear Unit-Long Short-Term Memory … …Journal of Computer Science, Vol. 20, Issue 10 · 17 Aug 2024 · 4,612 accessesView PDFCite
Research ArticleOpen accessIn the abstractTransverse Velocity, Transverse Boundary Shear Stress and Flow Deviation in Meandering Open ChannelsYoussef Ismail HafezThis study presents a novel approach for characterizing the mechanics of flow in mildly meandering open channels, specifically focusing on the development of a new vertical distribution equation for transverse velocity. Unlike existing equations in the literature that rely on complex logarithmic or integral forms or infinite series forms, which are impractical for hydraulic engineers, the proposed equation employs ordinary … …American Journal of Environmental Sciences, Vol. 20, Issue 1 · 25 Jul 2024 · 5,058 accessesView PDFCite
Review ArticleOpen accessIn the abstractThe Impact of Di-2-Ethylhexyl Phthalate (DEHP) in Focus on the Reproductive System and Toxicity in Rat or Mammalian ModelVenkataramanaiah Poli, Srinivasulu Reddy MotireddyAbsalan, F., Saremy, S., Mansouri, E., Moghadam, M. T., Moghadam, A. R. E., & Razie, G. (2016). Effects of Mono-(2-Ethylhexyl) Phthalate and Di-(2-Ethylhexyl) Phthalate Administrations on Oocyte Meiotic Maturation, Apoptosis and Gene Quantification in Mouse Model. Cell Journal, 18(4), 503–513. https://doi.org/10.22074/cellj.2016.4717 Acevedo‐Rodriguez, A., Kauffman, A. S., Cherrington, B. D., Borges, C. S., Roepke, T. A., & Laconi, M. (2018). Emerging … …American Journal of Pharmacology and Toxicology, Vol. 19, Issue 1 · 6 Jun 2024 · 12,990 accessesView PDFCite
Research ArticleOpen accessIn the abstractA CNN-KNN Based Recognition of Online Handwritten Symbols within Physics Expressions Using Contour-Based Bounding Box (CBBS) Segmentation TechniqueUjwala Kolte, Sachin Naik, Vidya KumbharArtieres, T., Marukatat, S., & Gallinari, P. (2007). Online Handwritten Shape Recognition Using Segmental Hidden Markov Models. IEEE Transactions on Pattern Analysis and Machine Intelligence, 29(2), 205–217. https://doi.org/10.1109/tpami.2007.38 Baró, A., Riba, P., Calvo-Zaragoza, J., & Fornés, A. (2019). From Optical Music Recognition to Handwritten Music Recognition: A baseline. Pattern Recognition Letters, 123, 1–8. https://doi.org/10.1016/j.patrec.2019.02.029 Bresler, M., Prua, D., & Hlavác, … …Journal of Computer Science, Vol. 20, Issue 7 · 7 May 2024 · 6,278 accessesView PDFCite
Research ArticleOpen accessIn the abstractAssociations of HSD17B1 Gene Expression with its DNA Methylation and Estradiol Level in Polycystic Ovary Syndrome Indonesian PatientsRina Puspita, Andon Hestiantoro et al.PCOS's origin and mechanism are still unknown. Epigenetics has been linked to PCOS in an increasing number of studies in recent years. The most extensively researched epigenetic alteration is DNA methylation. During organismal development, DNA methylation can control gene expression by altering transcription factor binding. The alterations in DNA methylation are directly associated with follicular development in PCOS. Studies show … …OnLine Journal of Biological Sciences, Vol. 24, Issue 2 · 8 Jan 2024 · 5,399 accessesView PDFCite