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59 articles for “Enzyme Levels”
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Research ArticleOpen accessIn the abstractMaximizing Fungal Growth in State-of-the-Art Tray Solid-State Fermenter: Aeration Strategies Optimized for Enhanced PerformanceMusaalbakri Abdul Manan, Colin WebbThis study introduced a tray fermenter, featuring eight layers of squared perforated trays, specifically designed for solid-state fermentation applications. It is named the multi-layer squared tray solid-state fermenter. The fermenter employs two aeration strategies with varying air flow rates to optimize fungal growth. Firstly, sterilized moistened air at 8 L/min flows from the bottom through the perforated trays. Secondly, a … …American Journal of Biochemistry and Biotechnology, Vol. 20, Issue 1 · 9 Apr 2024 · 6,453 accessesView PDFCite
Research ArticleOpen accessIn the abstractMomordica balsamina Fruit Extracts Enhances Selected Aspects of the Insulin Synthesis/Secretion PathwayAnanias Hodi Kgopa, Leshweni Jerry Shai, Motetelo Alfred MogalePrevious studies have suggested that crude plant extracts of the anti-diabetic medicinal plant, Momordica balsamina (MB) may exert their anti-diabetic effect through either enhancement of insulin sensitivity or inhibition of intestinal glucose absorption. However, the effects of these MB extracts on insulin synthesis and secretion are not well documented in the literature. Therefore, a main purpose of the current research … …American Journal of Biochemistry and Biotechnology, Vol. 16, Issue 4 · 17 Dec 2020 · 6,999 accessesView PDFCite
Research ArticleOpen accessIn the abstractComparative Assessment of Seroconversion in Poultry Vaccinated with Two Avian Influenza VaccinesBelan A. Astemirov, Seidigapbar M. Mamadaliyev, Yuliya V. Perfiliyeva, Marina A. KopochenyaFromAugust to December 2020, a new outbreak of H5 avian influenza caused anotherserious animal health emergency in Kazakhstan, leading to the deaths or cullingof more than 500 000 chickens. This outbreak renewed interest in developingprevention strategies for this re-emerging infection. In this study, weevaluated poultry seroconversion levels after two H5 vaccines. Regardless of age, productivity, and schemeof vaccination Super Nick … …American Journal of Animal and Veterinary Sciences, Vol. 17, Issue 3 · 22 Aug 2022 · 5,849 accessesView PDFCite
Research ArticleOpen accessIn the abstractModeling Hepatocellular Toxicity of Enavatuzumab, a Humanized Anti-TweakR AntibodyDonghee Choi, Yanhong Zhu, Debra Tien Chao et al.In a Phase 1 clinical study, treatment with enavatuzumab, a humanized monoclonal antibody to TweakR, resulted in liver toxicity in a subset of patients. The objective of this current study was to evaluate the ability of preclinical studies to predict liver toxicity in humans. Enavatuzumab was evaluated in cynomolgus monkeys, where serum liver enzyme and cytokine levels were measured and … …American Journal of Pharmacology and Toxicology, Vol. 12, Issue 2 · 9 Nov 2017 · 7,719 accessesView PDFCite
Research ArticleOpen accessIn the abstractAssociation of High-Affinity FcεRI-β intron 2 for IgE Gene Polymorphism and Atopic Diseases in an Algerian PopulationDahbia Ines Dahmani, Ikhlass Haj Salem, Jamila Chakir et al.Atopy is characterized by the production of a high level of IgE in response to common allergens. We examined the RsaI-in2 polymorphism of the FcεRI-β gene and its association with atopic asthma and comorbidity. The study population included 77 atopic asthmatics and 77 non-atopic, non-allergic and non-asthmatic controls. Atopic asthma was confirmed by the skin prick test and by IgE … …OnLine Journal of Biological Sciences, Vol. 17, Issue 4 · 1 Nov 2017 · 7,444 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffect of Stevia Consumption on Blood Pressure, Stress Hormone Levels and Anthropometrical Parameters in Healthy PersonsEmad A.S. Al-Dujaili, Husni Twaij, Yazan A. Bataineh et al.Stevia is a natural sweetener containing steviol glycosides known to be several times sweeter than sucrose. It is thought to have several beneficial properties though some evidence state it may have detrimental effects. The aim of this study was to investigate the potential beneficial or harmful effects of stevia consumption by exploring its effects on blood pressure, stress hormone levels … …American Journal of Pharmacology and Toxicology, Vol. 12, Issue 1 · 31 Aug 2017 · 25,775 accessesView PDFCite
Research ArticleOpen accessIn the abstractIn vitro Rumen Fermentability of the Pelleted Feed Containing Water Spinach (Ipomoea aquatica)Himmatul Hasanah, Eko Pangestu, Ali Agus, Joelal AchmadiAn in vitro technique based on two stages of batch culture was used to clarify fermentability and digestibility of pellet feed containing water spinach (Ipomoea aquatica). The portion of Pennisetum purpureum in the pellet feed was substituted with Ipomoea aquatica at respective levels of 0% (T1), 20% (T2), 40% (T3) and 60% (T4). The treatments were allocated in a completely … …American Journal of Animal and Veterinary Sciences, Vol. 15, Issue 1 · 27 Mar 2020 · 7,559 accessesView PDFCite
Research ArticleOpen accessIn the abstractOptimization of Enzymatic Hydrolysis of Freeze-Dried Sea Cucumber Powder with Response Surface Methodology and Its Antioxidant EvaluationYahui Pang, Jianfeng Sun, Qian LiuIn this study, freeze-dried sea cucumber powder was used as raw material and the preparation processing conditions were studied for hydrolysis of sea cucumber powder with neutral protease using Response Surface Methodology (RSM) to obtain a high concentration of sea cucumber polypeptide. The effects of hydrolysis temperature, pH, enzyme dosage and hydrolysis time on the degree of hydrolysis (DH) were … …American Journal of Biochemistry and Biotechnology, Vol. 12, Issue 4 · 17 Oct 2016 · 7,431 accessesView PDFCite
Research ArticleOpen accessIn the abstractINTERVENTION OF PHARMACOGENETIC PROFILING IN THERAPEUTICS OF KASHMIRI POPULATION, A LESSON LEARNED FROM CYP3A5*3 VARIANTAshaqullah Bhat, Aadil Wani, Rajinder Kaur et al.Human Cytochrome P450 3A, a variant of Cytochrome P-450- dependent monooxygenases is a major drug metabolizing enzyme. CYP3A has evolved to catalyze the biotransformation of its substrate. A great deal of inter-individual variation in expression levels exists for CYP3A5 gene. The common polymorphism in CYP3A5 that induces a cryptic splice site has been shown to cause a significant reduction in … …OnLine Journal of Biological Sciences, Vol. 14, Issue 3 · 10 Jul 2014 · 7,215 accessesView PDFCite
Research ArticleOpen accessIn the abstractCALCITONIN GENE-RELATED PEPTIDE IN SERUM AFTER SPONTANEOUS SUBARACHNOID HEMORRHAGEKarl-Michael Schebesch, Elisabeth Bruendl Andreas Hochreiter, Judith Scheitzach et al.Endogenous Calcitonin Gene-Related Peptide (CGRP) stored in perivascular nerve fibers around the cerebral arteries mediates vasodilation and regulates cerebral blood flow under physiological conditions. Increased levels of CGRP have been continually reported in patients with migraine, but the role of CGRP in the pathophysiology of Subarachnoid Hemorrhage (SAH) has not yet been sufficiently evaluated. Over 10 days, serum was prospectively … …Neuroscience International, Vol. 5, Issue 1 · 28 Jun 2014 · 7,588 accessesView PDFCite