Research ArticleOpen accessEvery word in the titleAssociation of Polymorphism in Growth and Differentiation Factor 5 Gene with Osteoarthritis KneeAbhishek Mishra, Divya Sanghi, Amar Chandra Sharma et al.The present study investigated to identify the association of polymorphism in GDF-5 gene with osteoarthritis in North Indian population. In a case-control study, 300 cases with knee osteoarthritis and an equal number of age and gender matched healthy controls were included. Cases were diagnosed using the ACR Guidelines of Knee Osteoarthritis (KOA). Clinical symptoms were assessed with the knee specific … …American Journal of Biochemistry and Biotechnology, Vol. 9, Issue 1 · 18 Mar 2013 · 9,417 accessesView PDFCite
Research ArticleOpen accessIn the keywordsTAGN-IDC: Implicit Discrete Constraints for Tsunami Aware Graph Neural Networks in Spatial Evacuation RoutingSularno, Wendi Boy, Putri Anggraini et al.Tsunami evacuation route requires rapid identification of safe evacuation paths under dynamically changing hazard conditions. A major challenge is incorporating hard binary road-blockage constraints caused by tsunami inundation while maintaining end-to-end differentiability for deep learning models. Existing approaches commonly rely on continuous relaxations or stochastic sampling techniques, which either compromise physical feasibility or increase computational complexity. This study proposes the … …Journal of Computer Science, Vol. 22, Issue 9 · 24 Sep 2026 · 704 accessesView PDFCite
Research ArticleOpen accessIn the keywordsAdipose-Derived Canine Mesenchymal Stem Cells in PLAY® MediaArjun Kulkarni, Bhavana N. V., Teena Mary Thomas et al.In veterinary medicine, stem cell-based therapies present promise for addressing orthopedic and degenerative conditions in canines. Mesenchymal Stem Cells (MSCs) possess unique regenerative, immunomodulatory, and differentiation capabilities. However, their efficacy relies on optimal in-vitro conditions. Prolonged expansion over passages leads to a gradual loss of stem cell traits, highlighting the importance of optimized culture conditions and media supplements. This study … …American Journal of Animal and Veterinary Sciences, Vol. 19, Issue 3 · 13 Jul 2024 · 5,598 accessesView PDFCite
Research ArticleOpen accessIn the keywordsIdentification of Long Non-coding RNAs Expressed During Early AdipogenesisRongkun Shen, Rachel A. Soeder, Henry D. Ophardt et al.Long non-coding RNAs (lncRNAs) are transcripts with a length of more than 200 nucleotides that lack protein-coding capacity. LncRNAs play important roles in the regulation of genes during many biological processes, development and disease progression, such as obesity. Obesity is an increasing health concern around the world. Although multiple studies linking lncRNAs and fully differentiated adipocytes have been published, the … …OnLine Journal of Biological Sciences, Vol. 19, Issue 4 · 30 Nov 2019 · 7,823 accessesView PDFCite
Research ArticleOpen accessIn the keywordsEffects of Vascular Endothelial Growth Factor (VEGF) on Dental Pulp Stem Cells (DPSC)Eric Mullins, Cale Forgues, Karl KingsleyDental Pulp Stem Cells (DPSCs) are non-embryonic, mesenchymal stem cells that may have significant potential for therapeutic and regenerative biomedical applications. Studies of DPSC differentiation have demonstrated the potential to form many tissue types, including neural, osteogenic and vascular precursors using cytokines and growth factors, such as Vascular Endothelial Growth Factor (VEGF). Eight previously isolated Dental Pulp Stem Cell (DPSC) … …Current Research in Medicine, Vol. 9, Issue 1 · 1 Jun 2019 · 13,831 accessesView PDFCite
Research ArticleOpen accessIn the keywordsExpression of microRNA miR-27, miR-124 and miR-218 Among Dental Pulp Stem Cell (DPSC) IsolatesMark Whiting, Karl KingsleyDental Pulp Stem Cells (DPSCs) are non-embryonic, mesenchymal stem cells that may have significant potential for therapeutic and regenerative biomedical applications. MicroRNAs are small non-coding RNA molecules that can act as transcriptional activators and repressors in many types of mesenchymal stem cells. To date, few studies have evaluated the expression or activity of microRNAs among dental pulp stem cells. Using … …Current Research in Dentistry, Vol. 9, Issue 1 · 1 Jan 2019 · 8,167 accessesView PDFCite
Research ArticleOpen accessIn the keywordsPrice-Value Potential for Near-Perfectly Competitive MarketsSergey K. AityanThis study introduces price-value potential to be used instead of price for market analysis by analogy with free energy or thermodynamic potential in physics. A conservation principle is proposed for price-value potential. It is shown that price-value potential provides a constructive way for market analysis by identifying variation of equilibrium prices and quantities for different products in market equilibrium. A … …American Journal of Economics and Business Administration, Vol. 3, Issue 4 · 21 Feb 2012 · 8,263 accessesView PDFCite
Research ArticleOpen accessIn the keywordsEffect of Activation Energies on Thermal Explosion in the Interior of the EarthAmos Oladele PopoolaProblem statement: Literatures have shown that thermal processes in the interior of the earth and the classical thermal explosion are analogous and that combustion processes are characterized by ignition and explosion. The heat released during the thermal explosion that occurs in the interior of the earth requires more attention. Approach: The study investigated the role of activation energies ratio in … …Journal of Mathematics and Statistics, Vol. 7, Issue 3 · 27 Jul 2011 · 7,277 accessesView PDFCite
Research ArticleOpen accessIn the keywordsPassage to the Differences for the BDF's MethodsAbdelouahab SalmiIn this study, we give an improvement to the backward differentiation formula (BDF). We use a formula for the differences that permits us to determine the new coefficients αi^ and γi ^in function of the classical coefficients αi and γi of this method. Our proposed approach decreases the error and the cost of computation. Numerical results for concrete problems are … …Journal of Mathematics and Statistics, Vol. 2, Issue 3 · 30 Sep 2006 · 6,412 accessesView PDFCite