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42 articles for “DNA damage”

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Review ArticleOpen accessIn the abstractUnveiling Skin Cancer: A Review of Deep Learning Techniques for DetectionGoutham Lal Shanmughamadom Harilal, Tamilselvi PanneerselvamEarly identification is essential for successful treatment and better patient outcomes since skin cancer is caused by damage to DNA in skin cells, which can result in genetic abnormalities and the possibility of metastasis. The present systematic review scrutinizes the efficacy and obstacles of early detection techniques, which differentiate between benign and malignant lesions by examining lesion attributes such as … …Journal of Computer Science, Vol. 21, Issue 9 · 23 Oct 2025 · 2,602 accessesView PDFCite
Review ArticleOpen accessIn the abstractReview on Different Algorithms and Techniques Used in Classification of Gender in SilkwormJyoti Sharma, Pradeep ChoukseySilkworm seed is the key factor for the success of sericulture industry. Silk seed production process at grain ages centre mainly involve procuration of seed cocoon, cutting of seed cocoon for pupae, separation of male and female pupae, emergence of moth, coupling of silk moth and further egg laying by female moth. Separation of male and female is very much … …Journal of Computer Science, Vol. 21, Issue 6 · 17 Jun 2025 · 4,031 accessesView PDFCite
Review ArticleOpen accessIn the abstractThe Impact of Di-2-Ethylhexyl Phthalate (DEHP) in Focus on the Reproductive System and Toxicity in Rat or Mammalian ModelVenkataramanaiah Poli, Srinivasulu Reddy MotireddyAbsalan, F., Saremy, S., Mansouri, E., Moghadam, M. T., Moghadam, A. R. E., & Razie, G. (2016). Effects of Mono-(2-Ethylhexyl) Phthalate and Di-(2-Ethylhexyl) Phthalate Administrations on Oocyte Meiotic Maturation, Apoptosis and Gene Quantification in Mouse Model. Cell Journal, 18(4), 503–513. https://doi.org/10.22074/cellj.2016.4717 Acevedo‐Rodriguez, A., Kauffman, A. S., Cherrington, B. D., Borges, C. S., Roepke, T. A., & Laconi, M. (2018). Emerging … …American Journal of Pharmacology and Toxicology, Vol. 19, Issue 1 · 6 Jun 2024 · 12,990 accessesView PDFCite
Research ArticleOpen accessIn the abstractAntioxidant Activity of Trilobatin and Its Inhibitory Effects on Oxidative Damage of Biological MacromoleculesYuhan Zhai, Yuqing Zhang, Yaping Li et al.Excessive levels of free radicals in the body cause oxidative damage to macromolecules by injuring DNA, proteins, and lipids, which leads to structural and functional defects and ultimately results in a number of illnesses. The antioxidation of trilobatin and its inhibitory activity of trilobatin on oxidative damage of biological macromolecules have not been thoroughly investigated. In this research, the effects … …American Journal of Biochemistry and Biotechnology, Vol. 19, Issue 4 · 28 Oct 2023 · 5,466 accessesView PDFCite
Research ArticleOpen accessIn the abstractInfluence of Intracellular Reactive Oxygen Species in Several Spermatozoa Activity in Indonesian Ongole Bull Cryopreserved SpermKurniawan Dwi Prihantoko, Asmarani Kusumawati, Mulyoto Pangestu et al.Certain factors may affect sperm motility and integrity in a freezing process. Reactive Oxygen Species (ROS) is essential in damaging the sperm, as the previous study revealed that ROS is a major cause damaging the membrane of spermatozoa. This study aimed to understand ROS production and its interaction within the motility, mitochondrial activity and DNA damage to the cryopreservation process … …American Journal of Animal and Veterinary Sciences, Vol. 17, Issue 1 · 26 Jan 2022 · 6,842 accessesView PDFCite
Research ArticleOpen accessIn the abstractTherapeutic Effects of Turnera diffusa Extract Against Amitriptyline-Induced Toxic Hepatic InflammationAhmed F. Hasan, Thulfiqar F. Mutar, Ehab Moustafa Tousson, Shatha Ghazi FelembanTricyclic Antidepressants Including Amitriptyline (AMI), stop the reabsorption of norepinephrine and serotonin, so the levels of transmitters is elevated in the brain to lead to several side effects. Therefore, current study aimed to assay liver dysfunction that attended by AMI administration and monitoring of damiana Turnera diffuse role as adjuvant therapy to improving amitriptyline hepatic effects in male rats. 60 … …OnLine Journal of Biological Sciences, Vol. 21, Issue 2 · 29 Jun 2021 · 8,286 accessesView PDFCite
Review ArticleOpen accessIn the abstractMechanistic Insights of Actions of Metal Nanoparticles on Multidrug-Resistant BacteriaSeham S. Alzahrani, Hani Mohammed Ali, Mohamed M. AhmedMultidrug-Resistant bacteria (MDR) are the most serious threat to public health. The number of infections caused by resistant strains is on the rise all over the world. At this time, new techniques for developing antimicrobial drugs are becoming necessary. Metallic Nanoparticles (MNPs) in the biomedical field are one of the most promising methods to overcome antibiotic resistance. Nanoparticles have recently … …OnLine Journal of Biological Sciences, Vol. 21, Issue 2 · 22 Jun 2021 · 6,374 accessesView PDFCite
Research ArticleOpen accessIn the abstractBiotic and Abiotic Factors of Sperm nDNA Fragmentation in Farm AnimalsBaylar Iolchiev, Natalya Volkova, Pavel Klenovitskiy et al.Infertility and subfertility are among the global challenges of our time. Fertility in livestock farming is not only biologically important, it is also economically important. The aim of this study was to study the effect of these factors on sperm chromatin nucleus and to assess the impact of the fragmentation index degree on bull reproductive performance. The influence of abiotic … …American Journal of Animal and Veterinary Sciences, Vol. 16, Issue 1 · 11 Mar 2021 · 6,714 accessesView PDFCite
Research ArticleOpen accessIn the abstractGlutathione S-transferase (T1 & M1) Null Genotypes as Risk Determinants in Sudanese for Developing Type Two Diabetes MellitusGaafar Mahmoud, Hisham Mohamed Abdelrahim, Abed Al Salam Aljahmany, Eltayeb Mohamed Ahmed TayrabGlutathione S-transferases (GSTT1 and GSTM1) are globular proteins responsible for the detoxification of xenobiotics and the prevention of oxidative damage. Functional polymorphisms of the antioxidant glutathione and enzymes have a role in the pathogenicity of T2DM and its complications. The present study is aimed to assess association between GSTM1 and GSTT1 genetic polymorphisms with T2DM in Sudanese people. This case-control … …American Journal of Biochemistry and Biotechnology, Vol. 16, Issue 3 · 16 Oct 2020 · 6,423 accessesView PDFCite
Research ArticleOpen accessIn the abstractAssessment of the Toxic Effects of Chitosan-Coated Magnetite Nanoparticles on Drosophila melanogasterDoris Vela, Jonathan Rondal, Sofía Cárdenas et al.Nanoparticles are a cause for concern because of their potential toxic effects on human health and the environment. The aim of this study was to assess the toxic effect of chitosan-coated magnetite nanoparticles (11.00±4.7 nm) on Drosophila melanogaster through the observation of hemolymph composition, DNA damage, larval survival and lifespan of flies. Chitosan-coated magnetite nanoparticles were synthesized by co-precipitation method. … …American Journal of Applied Sciences, Vol. 17, Issue 1 · 25 Sep 2020 · 7,882 accessesView PDFCite