EditorialOpen accessIn the abstractNeutrophil Extracellular Traps as Therapeutic Targets for Inflammatory DiseaseRory R. KoenenNeutrophilic granulocytes, or neutrophils are the most abundant circulating white blood cell and constitute a first line of defense against pathogens. They are characterized by a large polymorphic lobular nucleus and the presence of many secretory granules in their cytoplasm. Neutrophils are essential for a functional host defense, as is evidenced by the occurrence of severe infections in individuals with … …American Journal of Pharmacology and Toxicology, Vol. 9, Issue 4 · 25 Feb 2015 · 8,737 accessesView PDFCite
EditorialOpen accessIn the abstractTo NET or not to NETJadwiga JablonskaBranzk, N., A. Lubojemska, S.E. Hardison, Q. Wang and V. Papayannopoulos et al., 2014. Neutrophils sense microbe size and selectively release neutrophil extracellular traps in response to large pathogens. Nat. Immunol.,15: 1017-1025. DOI: 10.1038/ni.2987 Brinkmann, V., U. Reichard, C. Goosmann, B. Fauler and A. Zychlinsky et al., 2004. Neutrophil extracellular traps kill bacteria. Science, 303: 1532-1535. DOI: 10.1126/science.1092385 Cools-Lartigue, J., … …American Journal of Immunology, Vol. 10, Issue 4 · 3 Dec 2014 · 8,383 accessesView PDFCite